iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117638

Ensembl Protein ID

ENSTRUP00000011596.1

UniProt Accession

H2SGR4; H2SGR4_TAKRU

Protein Name

Histone-lysine N-methyltransferase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000004854.1	ENSTRUT00000011656.1	ENSTRUP00000011596.1
ENSTRUG00000004854.1	ENSTRUT00000011657.1	ENSTRUP00000011597.1
ENSTRUG00000004854.1	ENSTRUT00000011658.1	ENSTRUP00000011598.1
ENSTRUG00000004854.1	ENSTRUT00000011659.1	ENSTRUP00000011599.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.40e-12	48.1	790	830

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 790  WCFVCSKGGQ----LLCCESCPAAFHPDCLNIA----MPDGS-WFCNDCR 830
           8*********....*******************....9***8.******8 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MDSKGSSLPS MPEPANPVSM KQLPEPLSVR KNGGDMSSDH SMLMDKAAAH LAATLQDSVL 60
QKMASHSHGN HSHERLKDLT SLVLNGDQDT LPKLSTPEQP LLKSAEVPTT NGTHQHNCSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAGCA AAGGGAGCTC CCTGCCTTCG ATGCCTGAAC CAGCCAACCC CGTCAGCATG 60
AAGCAGCTAC CAGAGCCCCT CAGCGTGCGA AAGAATGGAG GAGACATGAG CAGCGACCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0051216--P:cartilage development
GO:0048706--P:embryonic skeletal system development
GO:0010452--P:histone H3-K36 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002181	Ailuropoda melanoleuca	50.34	0.00e+00	1233.00
IUUC-Apl-003677	Anas platyrhynchos	50.30	0.00e+00	1244.00
IUUC-Aca-004278	Anolis carolinensis	61.13	0.00e+00	1065.00
IUUC-Ame-011932	Astyanax mexicanus	72.56	0.00e+00	1170.00
IUUC-Bta-012522	Bos taurus	49.30	0.00e+00	1194.00
IUUC-Bra-017530	Brassica rapa	32.66	3.00e-14	73.90
IUUC-Cja-018908	Callithrix jacchus	50.11	0.00e+00	1219.00
IUUC-Cfa-020894	Canis familiaris	50.11	0.00e+00	1254.00
IUUC-Cpo-021982	Cavia porcellus	49.41	0.00e+00	1223.00
IUUC-Csa-023807	Chlorocebus sabaeus	49.81	0.00e+00	1211.00
IUUC-Cho-024405	Choloepus hoffmanni	76.13	7.00e-74	271.00
IUUC-Dre-027492	Danio rerio	79.39	0.00e+00	1193.00
IUUC-Dno-030020	Dasypus novemcinctus	46.13	0.00e+00	1000.00
IUUC-Dor-031103	Dipodomys ordii	64.03	0.00e+00	905.00
IUUC-Dme-032193	Drosophila melanogaster	36.89	1.00e-119	425.00
IUUC-Ete-032488	Echinops telfairi	47.00	0.00e+00	1071.00
IUUC-Eca-034066	Equus caballus	50.63	0.00e+00	1241.00
IUUC-Eeu-035199	Erinaceus europaeus	55.22	1.00e-113	405.00
IUUC-Fca-035434	Felis catus	52.72	0.00e+00	1137.00
IUUC-Fal-037113	Ficedula albicollis	49.63	0.00e+00	1248.00
IUUC-Gmo-039686	Gadus morhua	76.52	0.00e+00	1126.00
IUUC-Gga-040273	Gallus gallus	50.22	0.00e+00	1240.00
IUUC-Gac-042123	Gasterosteus aculeatus	84.82	0.00e+00	1312.00
IUUC-Ggo-044643	Gorilla gorilla	50.94	0.00e+00	1236.00
IUUC-Hsa-046380	Homo sapiens	50.11	0.00e+00	1217.00
IUUC-Itr-048658	Ictidomys tridecemlineatus	67.92	0.00e+00	1020.00
IUUC-Lch-050217	Latimeria chalumnae	61.74	0.00e+00	1082.00
IUUC-Loc-052766	Lepisosteus oculatus	74.65	0.00e+00	1146.00
IUUC-Laf-053780	Loxodonta africana	51.03	0.00e+00	1228.00
IUUC-Mcc-054928	Macaca mulatta	50.49	0.00e+00	1222.00
IUUC-Mga-059576	Meleagris gallopavo	50.45	0.00e+00	1235.00
IUUC-Mmr-061045	Microcebus murinus	49.59	0.00e+00	1233.00
IUUC-Mdo-062576	Monodelphis domestica	49.23	0.00e+00	1209.00
IUUC-Mmu-063640	Mus musculus	49.40	0.00e+00	1219.00
IUUC-Mpu-066512	Mustela putorius furo	50.26	0.00e+00	1238.00
IUUC-Nle-069896	Nomascus leucogenys	50.27	0.00e+00	1159.00
IUUC-Ont-072197	Oreochromis niloticus	90.53	0.00e+00	1265.00
IUUC-Ocu-074758	Oryctolagus cuniculus	48.95	0.00e+00	1182.00
IUUC-Obr-076178	Oryza brachyantha	29.65	2.00e-11	64.70
IUUC-Olo-080702	Oryza longistaminata	39.63	8.00e-44	172.00
IUUC-Oga-088702	Otolemur garnettii	47.49	0.00e+00	1009.00
IUUC-Oar-089736	Ovis aries	72.24	0.00e+00	933.00
IUUC-Ptr-091055	Pan troglodytes	50.11	0.00e+00	1217.00
IUUC-Pan-092752	Papio anubis	71.22	0.00e+00	1020.00
IUUC-Psi-093620	Pelodiscus sinensis	50.89	0.00e+00	1267.00
IUUC-Ppa-095277	Physcomitrella patens	31.03	2.00e-13	70.90
IUUC-Pfo-097464	Poecilia formosa	68.38	0.00e+00	1689.00
IUUC-Pab-098051	Pongo abelii	51.21	0.00e+00	1231.00
IUUC-Pca-100273	Procavia capensis	51.54	0.00e+00	1205.00
IUUC-Pva-102473	Pteropus vampyrus	68.12	0.00e+00	910.00
IUUC-Rno-105056	Rattus norvegicus	50.15	0.00e+00	1228.00
IUUC-Sha-107494	Sarcophilus harrisii	49.74	0.00e+00	1213.00
IUUC-Sit-110333	Setaria italica	30.99	1.00e-10	62.00
IUUC-Sar-113310	Sorex araneus	53.66	0.00e+00	1045.00
IUUC-Ssc-116344	Sus scrofa	50.04	0.00e+00	1224.00
IUUC-Tgu-116786	Taeniopygia guttata	50.52	0.00e+00	1238.00
IUUC-Tsy-118937	Tarsius syrichta	70.50	0.00e+00	1042.00
IUUC-Tni-120452	Tetraodon nigroviridis	88.47	0.00e+00	1437.00
IUUC-Tbe-127291	Tupaia belangeri	67.43	0.00e+00	988.00
IUUC-Xtr-132673	Xenopus tropicalis	48.30	0.00e+00	1161.00
IUUC-Xma-133695	Xiphophorus maculatus	89.00	0.00e+00	1239.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence