iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sja-107712

Ensembl Protein ID

EEB05717

UniProt Accession

B6JWG6; B6JWG6_SCHJY

Genbank Protein ID

EEB05717.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

KE651166

Gene Name

SJAG_00742

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SJAG_00742	EEB05717	EEB05717

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	6.90e-69	230.6	193	767

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle...kkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEfla 97
           Gl+Nlg+tCY+NSv+Q+L++ + + +++ +   + +    ++  ++   ++l+++ ++++ ++  +++  ++ p+ +++ +++ +++f+++ qqDa+E+++
   Q: 193  GLQNLGATCYFNSVMQVLTSSEYIHDAFSQhpfRPPTISGASLMEDCGSSMLHTFVNFLQVFYhaNGSIPSYRPSCMFSEIQRRHPHFTESVQQDAHELFR 293
           9*****************************7754444444433344445666666666666666678888******************************* PP
   S: 98   flldql.eeelkkeknkpkeeeeeedkselsde................................................................aeek 133
           +lld+l +eelk  +nk++ ee+ +++ +l  +                                                                 ++ 
   Q: 294  VLLDELiQEELK--ENKRRLEERTQAQPSLGVKtqgalstqlqktrpecsldtlappvaspfktneqcqhtftffdapttpidvdcvtqrpvelppvTDST 392
           ****97366663..46666666666555555558899***********************************************************99999 PP
   S: 134  kkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke................................................. 185
            ++++++++  lF g + s ++c  c+n++  +ep +dlslp+  +     +                                                 
   Q: 393  VPSEQTTVLGSLFSGNIVSVVMCSCCHNITRIREPIYDLSLPIMHDPPH-IRrrdrfqqalkrgfsfgskrsknmpkiivnpveeessllpsfpvpnssss 492
           9*******************************************88844.335899999****************************************** PP
   S: 186  ........................................................................slqdcLesftkeeelegenkyycekckkk 214
                                                                                   s+++cLe+f+ +e+leg+n++ ce+c+k+
   Q: 493  alefdspfgesldtqsslrlcspnsqpgflsedslpsmdssfrgstptserhlssslmqtftdktvlyvepkSVHECLENFVHTEKLEGDNMFACEECYKL 593
           ***************************************************************************************************99 PP
   S: 215  qe..............................aekklklk.klPevLilhLkRf...sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLi 281
           ++                              a kk++l+  l+++L+lhLkRf     ++ + +++k+++ +ef   Ld++ f+  + ++  +   Y+L+
   Q: 594  SKhrcrspsehehelsspddsvsekqpyvfrkAYKKIMLDvPLSRILVLHLKRFthkASHNGKVVSKKLTQPIEFTPILDMNDFVLPEHQEP-NGIMYRLT 693
           9999999999999999999999999999999988888887369***********6642233346789*********9********9977665.69****** PP
   S: 282  avvvHsGslssGHYvayvkn.....................ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           +++vH G+l+sGHY++yv +                     e+++Wl+++Ds+V+ v++eev +   ++aY+lfY+r
   Q: 694  GIIVHAGTLDSGHYTCYVLShkcvtrqtvdepelkkdepgmEERQWLYISDSTVKLVTWEEVSR---AEAYMLFYER 767
           ********************99****9999999999999998999*******************...********98 PP

Organism

Schizosaccharomyces japonicus

Protein Sequence
(Fasta)

MEDVIEQSLI SLHLPADKHT PLEASAEERS EPVKVCPHLK KSVKLPSIKS NARVLRDPSK 60
TLCVTCSKEG SRAVNYEDLM LCTFCGYLFC ADNEKQHVQA HMKKNNKHCV AMNLVTRETY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGACG TTATTGAACA ATCTCTTATT TCCCTCCACT TGCCTGCGGA CAAGCATACG 60
CCTCTTGAAG CATCAGCAGA AGAGCGTTCT GAACCAGTGA AAGTTTGTCC TCACTTAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000997	Aegilops tauschii	32.24	1.00e-15	77.00
IUUC-Aml-002331	Ailuropoda melanoleuca	29.87	2.00e-22	99.00
IUUC-Apl-003512	Anas platyrhynchos	29.23	2.00e-24	105.00
IUUC-Aca-004284	Anolis carolinensis	26.94	5.00e-22	97.80
IUUC-Aly-006422	Arabidopsis lyrata	32.91	4.00e-19	88.60
IUUC-Ath-006732	Arabidopsis thaliana	32.91	7.00e-18	84.30
IUUC-Ame-010735	Astyanax mexicanus	32.86	4.00e-23	100.00
IUUC-Bta-012880	Bos taurus	24.02	2.00e-18	85.90
IUUC-Bdi-014465	Brachypodium distachyon	33.55	1.00e-19	89.70
IUUC-Bol-015191	Brassica oleracea	28.69	4.00e-16	78.60
IUUC-Cja-019144	Callithrix jacchus	28.33	4.00e-22	98.20
IUUC-Cfa-020971	Canis familiaris	29.69	1.00e-22	99.40
IUUC-Cpo-022497	Cavia porcellus	27.76	1.00e-21	96.30
IUUC-Csa-024103	Chlorocebus sabaeus	29.15	6.00e-21	94.00
IUUC-Csv-026075	Ciona savignyi	28.64	4.00e-17	80.90
IUUC-Dre-028106	Danio rerio	30.52	3.00e-21	95.10
IUUC-Dno-029409	Dasypus novemcinctus	29.02	2.00e-20	92.40
IUUC-Dor-030438	Dipodomys ordii	26.78	3.00e-18	85.50
IUUC-Eca-034211	Equus caballus	28.63	2.00e-23	102.00
IUUC-Eeu-034835	Erinaceus europaeus	29.02	3.00e-20	91.70
IUUC-Fca-035947	Felis catus	30.84	3.00e-22	98.60
IUUC-Fal-037029	Ficedula albicollis	30.53	4.00e-21	94.70
IUUC-Gmo-039228	Gadus morhua	31.58	4.00e-20	91.30
IUUC-Gga-040823	Gallus gallus	30.04	2.00e-24	105.00
IUUC-Gac-042406	Gasterosteus aculeatus	31.10	1.00e-21	96.30
IUUC-Gma-043919	Glycine max	29.30	2.00e-15	76.60
IUUC-Ggo-045402	Gorilla gorilla	28.94	5.00e-22	97.80
IUUC-Hsa-046430	Homo sapiens	27.62	3.00e-21	95.10
IUUC-Hvu-047146	Hordeum vulgare	32.89	4.00e-19	88.60
IUUC-Itr-048855	Ictidomys tridecemlineatus	27.35	1.00e-18	85.50
IUUC-Lch-049547	Latimeria chalumnae	26.18	4.00e-21	94.70
IUUC-Lpe-050703	Leersia perrieri	33.13	1.00e-20	93.20
IUUC-Loc-052842	Lepisosteus oculatus	30.05	2.00e-19	89.00
IUUC-Laf-053988	Loxodonta africana	27.98	9.00e-21	93.60
IUUC-Mcc-055491	Macaca mulatta	29.06	3.00e-23	101.00
IUUC-Meu-056256	Macropus eugenii	27.30	1.00e-22	99.80
IUUC-Mtr-057945	Medicago truncatula	33.56	4.00e-17	82.00
IUUC-Mla-059026	Melampsora laricipopulina	33.97	2.00e-18	85.50
IUUC-Mga-059833	Meleagris gallopavo	30.42	1.00e-25	108.00
IUUC-Mvi-060391	Microbotryum violaceum	30.27	6.00e-17	80.90
IUUC-Mmr-060952	Microcebus murinus	30.17	2.00e-22	99.40
IUUC-Mdo-062642	Monodelphis domestica	25.41	2.00e-22	99.00
IUUC-Mmu-063945	Mus musculus	27.78	3.00e-21	95.10
IUUC-Mpu-065944	Mustela putorius furo	30.96	2.00e-21	95.50
IUUC-Mlu-067049	Myotis lucifugus	28.81	7.00e-23	100.00
IUUC-Nle-069828	Nomascus leucogenys	28.94	1.00e-22	99.80
IUUC-Opr-070969	Ochotona princeps	28.12	2.00e-20	92.00
IUUC-Ont-072121	Oreochromis niloticus	31.13	3.00e-21	95.50
IUUC-Oan-073656	Ornithorhynchus anatinus	31.17	4.00e-25	108.00
IUUC-Ocu-074323	Oryctolagus cuniculus	31.17	6.00e-23	100.00
IUUC-Oba-075094	Oryza barthii	34.87	4.00e-20	92.00
IUUC-Obr-076743	Oryza brachyantha	34.01	1.00e-20	93.20
IUUC-Ogl-077545	Oryza glaberrima	28.29	2.00e-14	72.40
IUUC-Ogu-078851	Oryza glumaepatula	34.87	3.00e-20	92.00
IUUC-Oin-079402	Oryza indica	34.87	4.00e-20	92.00
IUUC-Olo-080431	Oryza longistaminata	34.87	3.00e-20	92.00
IUUC-Ome-081580	Oryza meridionalis	34.87	4.00e-20	92.00
IUUC-Oni-082644	Oryza nivara	34.87	4.00e-20	92.00
IUUC-Opu-083452	Oryza punctata	33.55	2.00e-20	92.80
IUUC-Oru-084546	Oryza rufipogon	34.87	4.00e-20	92.00
IUUC-Osa-085858	Oryza sativa	34.87	4.00e-20	91.70
IUUC-Ola-087238	Oryzias latipes	30.43	7.00e-20	90.50
IUUC-Oga-088379	Otolemur garnettii	29.34	2.00e-22	99.00
IUUC-Oar-089718	Ovis aries	27.63	1.00e-17	82.80
IUUC-Ptr-091358	Pan troglodytes	27.78	9.00e-22	96.70
IUUC-Pan-092023	Papio anubis	29.06	3.00e-23	101.00
IUUC-Psi-093256	Pelodiscus sinensis	28.38	1.00e-20	93.20
IUUC-Ppa-095622	Physcomitrella patens	34.00	5.00e-17	81.60
IUUC-Pfo-097285	Poecilia formosa	31.10	2.00e-21	95.90
IUUC-Pab-098539	Pongo abelii	28.94	2.00e-22	99.00
IUUC-Pop-099136	Populus trichocarpa	33.76	4.00e-19	88.60
IUUC-Pca-101069	Procavia capensis	28.44	2.00e-19	89.00
IUUC-Pva-102985	Pteropus vampyrus	28.63	4.00e-24	104.00
IUUC-Rno-105538	Rattus norvegicus	28.63	2.00e-22	99.00
IUUC-Sha-107022	Sarcophilus harrisii	28.17	6.00e-21	94.00
IUUC-Spo-108149	Schizosaccharomyces pombe	42.44	2.00e-60	225.00
IUUC-Sit-110283	Setaria italica	35.53	6.00e-20	91.30
IUUC-Sly-111491	Solanum lycopersicum	34.01	3.00e-20	92.40
IUUC-Stu-112820	Solanum tuberosum	32.83	4.00e-21	95.10
IUUC-Sbi-113785	Sorghum bicolor	34.01	5.00e-17	81.60
IUUC-Ssc-115870	Sus scrofa	28.07	7.00e-23	100.00
IUUC-Tgu-116907	Taeniopygia guttata	29.15	2.00e-24	105.00
IUUC-Tru-117835	Takifugu rubripes	32.55	2.00e-22	99.00
IUUC-Tsy-118869	Tarsius syrichta	28.51	3.00e-22	98.60
IUUC-Tni-119716	Tetraodon nigroviridis	30.14	1.00e-22	99.40
IUUC-Tae-125351	Triticum aestivum	32.24	1.00e-15	76.60
IUUC-Tbe-128041	Tupaia belangeri	26.34	8.00e-19	87.00
IUUC-Ttr-128901	Tursiops truncatus	28.07	1.00e-22	99.80
IUUC-Xtr-131869	Xenopus tropicalis	31.58	3.00e-23	102.00
IUUC-Xma-133100	Xiphophorus maculatus	31.10	8.00e-22	97.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence