iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Spo-108095

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Probable ubiquitin carboxyl-terminal hydrolase 9; Deubiquitinating enzyme 9; Ubiquitin thioesterase 9; Ubiquitin-specific-processing protease 9

Genbank Nucleotide ID

CU329671

Gene Name

ubp9; SPBC1703.12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPBC1703.12	SPBC1703.12.1	SPBC1703.12.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.40e-86	287.5	42	422

Active Site

Position(s)	Description	Evidence
50	Nucleophile	ECO:0000255\|PROSITE-ProRule:PRU10093}
375	Proton acceptor	ECO:0000255\|PROSITE-ProRule:PRU10093}

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle........kkkeklneenp........................................... 42
           Gl+N gNtCY+ SvL +L++++++r+ l++        ++k+ + ++n+                                           
   Q: 42   GLTNYGNTCYVSSVLVSLYHLKPFRDSLNSyplpsappNFKSVCTKTNHpessssrhskkksmenrksslygsnginscgcvdisnvgsesg 133
           9*****************************99999999666666666557777777788899999999************************ PP
   S: 43   ..............kepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeee 118
                          ++k++++++l++l  ++   +++ +  sp++++++l++ +e f++++qqDa+Ef++fll+++ e+l           
   Q: 134  tkhqivvgesncsaYGMKENIYTCLKDLYCSVSccDCRYGICSPERFIQVLRRDNEAFRSTQQQDAHEFFNFLLNSVTETL----------- 214
           ******9999999999999************9999**********************************************........... PP
   S: 119  eeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycek 210
                   ++   ++ +  ++++++ lF+g+l+s++kcl+c+n++sr+e+fldls+++++++     s+++cL+sf++ e+l ++nk++c+ 
   Q: 215  --------DEYYGNHSDVMHPKWVHSLFEGTLTSETKCLTCENITSRDESFLDLSIDIENHT-----SVTSCLRSFSASEMLSSKNKFHCDV 293
           ........2234455778899*****************************************.....9************************ PP
   S: 211  ckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvkn 301
           ck++qeaek++k+kklP++L+lhLkRf+++e+q+ + k++  + f  e+ l  f+t+++ + + ++ Y L++v+vH G +++ GHYv++v+ 
   Q: 294  CKSLQEAEKRMKIKKLPKILSLHLKRFKYNETQEGHDKLFYTIVFTNEMRL--FTTTEDAE-NAERMYYLSSVIVHVGgGPHRGHYVSIVRT 382
           *********************************************977777..56664444.459*************************** PP
   S: 302  ekgkWllfdDskVtevkeeevleetg.....staYvlfYk 336
           ++ +W+lfdD++Vt+v+e+  +++ g     +taYvlfY+
   Q: 383  KTYGWVLFDDENVTPVNENYLQRFFGdqpgqATAYVLFYT 422
           ***********************999*************8 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Ubiquitin C-terminal hydrolase involved in regulating actin dynamics and/or endocytosis at cell tips and septa.

Protein Sequence
(Fasta)

MSLLRWMGMN SPGSTDRRKS TWEAELPKPS IRPETLTDRF YGLTNYGNTC YVSSVLVSLY 60
HLKPFRDSLN SYPLPSAPPN FKSVCTKTNH PESSSSRHSK KKSMENRKSS LYGSNGINSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAGATTATG ATCACCAACG TACGCCCCTT TCTGAGCGCG TGAAAGCTTC CCTTTGCGTT 60
CACTTCCCCG CTGTGCTTGG TTTGTAAACT TAGCATCCTT TAGTTCAACT CAGCATGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0378--Hydrolase
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0032153--C:cell division site
GO:0030428--C:cell septum
GO:0051286--C:cell tip
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0006897--P:endocytosis
GO:0035871--P:protein K11-linked deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

spo:SPBC1703.12

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000934	Aegilops tauschii	37.89	4.00e-73	267.00
IUUC-Aml-001964	Ailuropoda melanoleuca	46.44	8.00e-78	281.00
IUUC-Atr-002650	Amborella trichopoda	45.15	3.00e-72	263.00
IUUC-Apl-003411	Anas platyrhynchos	46.94	2.00e-77	280.00
IUUC-Aca-005212	Anolis carolinensis	46.44	2.00e-77	280.00
IUUC-Aly-005830	Arabidopsis lyrata	45.34	1.00e-72	264.00
IUUC-Ath-007280	Arabidopsis thaliana	45.34	1.00e-72	264.00
IUUC-Ago-007871	Ashbya gossypii	39.94	4.00e-62	230.00
IUUC-Acl-008239	Aspergillus clavatus	43.98	2.00e-103	368.00
IUUC-Afl-008602	Aspergillus flavus	44.09	4.00e-102	363.00
IUUC-Afu-008816	Aspergillus fumigatus	43.06	8.00e-98	349.00
IUUC-Ani-009137	Aspergillus nidulans	44.55	5.00e-100	356.00
IUUC-Ang-009703	Aspergillus niger	54.30	4.00e-96	343.00
IUUC-Aor-009901	Aspergillus oryzae	54.05	1.00e-94	338.00
IUUC-Ate-010431	Aspergillus terreus	52.60	6.00e-94	336.00
IUUC-Ame-011015	Astyanax mexicanus	45.95	1.00e-76	277.00
IUUC-Bgr-012071	Blumeria graminis	40.13	5.00e-97	346.00
IUUC-Bta-012981	Bos taurus	46.60	5.00e-77	279.00
IUUC-Bci-013837	Botrytis cinerea	42.99	8.00e-104	369.00
IUUC-Bdi-014008	Brachypodium distachyon	43.73	2.00e-71	260.00
IUUC-Bol-015138	Brassica oleracea	45.78	2.00e-72	263.00
IUUC-Bra-016956	Brassica rapa	45.02	2.00e-72	264.00
IUUC-Cel-018379	Caenorhabditis elegans	38.55	3.00e-70	257.00
IUUC-Cja-018831	Callithrix jacchus	46.10	3.00e-77	279.00
IUUC-Cfa-020534	Canis familiaris	46.44	7.00e-78	281.00
IUUC-Cpo-021703	Cavia porcellus	46.44	8.00e-78	281.00
IUUC-Cre-022711	Chlamydomonas reinhardtii	45.52	2.00e-60	224.00
IUUC-Csa-023841	Chlorocebus sabaeus	44.71	9.00e-74	268.00
IUUC-Cho-024902	Choloepus hoffmanni	35.25	2.00e-50	190.00
IUUC-Cin-025659	Ciona intestinalis	50.50	2.00e-58	217.00
IUUC-Csv-025828	Ciona savignyi	52.55	1.00e-59	221.00
IUUC-Cgl-026611	Colletotrichum gloeosporioides	39.69	3.00e-106	377.00
IUUC-Cne-026900	Cryptococcus neoformans	41.98	2.00e-62	231.00
IUUC-Dre-027845	Danio rerio	46.28	5.00e-77	279.00
IUUC-Dno-029460	Dasypus novemcinctus	46.44	9.00e-78	281.00
IUUC-Dor-030972	Dipodomys ordii	47.06	4.00e-67	246.00
IUUC-Dse-031470	Dothistroma septosporum	49.52	7.00e-89	319.00
IUUC-Dme-032038	Drosophila melanogaster	50.98	3.00e-60	223.00
IUUC-Ete-032659	Echinops telfairi	48.88	4.00e-49	186.00
IUUC-Eca-033439	Equus caballus	46.44	7.00e-78	281.00
IUUC-Eeu-034916	Erinaceus europaeus	47.03	2.00e-60	223.00
IUUC-Fca-035524	Felis catus	46.78	5.00e-78	282.00
IUUC-Fal-036833	Ficedula albicollis	46.94	2.00e-77	280.00
IUUC-Fox-037682	Fusarium oxysporum	42.56	4.00e-101	360.00
IUUC-Fso-038299	Fusarium solani	43.94	4.00e-98	350.00
IUUC-Gmo-038763	Gadus morhua	46.13	8.00e-78	281.00
IUUC-Ggr-039806	Gaeumannomyces graminis	38.99	1.00e-100	358.00
IUUC-Gga-041151	Gallus gallus	46.94	2.00e-77	280.00
IUUC-Gac-041967	Gasterosteus aculeatus	46.46	2.00e-78	283.00
IUUC-Gma-042927	Glycine max	39.71	9.00e-78	281.00
IUUC-Ggo-044659	Gorilla gorilla	44.71	1.00e-73	267.00
IUUC-Hsa-045700	Homo sapiens	46.10	3.00e-77	279.00
IUUC-Hvu-047692	Hordeum vulgare	44.48	4.00e-71	259.00
IUUC-Itr-049082	Ictidomys tridecemlineatus	46.44	8.00e-78	281.00
IUUC-Kpa-049250	Komagataella pastoris	47.65	1.00e-88	318.00
IUUC-Lch-050435	Latimeria chalumnae	45.76	2.00e-76	277.00
IUUC-Lpe-051368	Leersia perrieri	42.99	1.00e-69	254.00
IUUC-Loc-051968	Lepisosteus oculatus	45.76	1.00e-76	277.00
IUUC-Lma-053300	Leptosphaeria maculans	39.96	2.00e-99	354.00
IUUC-Laf-053887	Loxodonta africana	46.44	7.00e-78	281.00
IUUC-Mcc-055701	Macaca mulatta	46.10	4.00e-77	279.00
IUUC-Mor-057072	Magnaporthe oryzae	42.95	4.00e-102	363.00
IUUC-Mpo-057424	Magnaporthe poae	39.17	2.00e-98	351.00
IUUC-Mtr-057715	Medicago truncatula	45.70	6.00e-73	265.00
IUUC-Mla-059142	Melampsora laricipopulina	52.06	9.00e-89	320.00
IUUC-Mga-059195	Meleagris gallopavo	46.94	2.00e-77	280.00
IUUC-Mvi-060357	Microbotryum violaceum	53.68	5.00e-77	280.00
IUUC-Mmr-060751	Microcebus murinus	46.44	7.00e-78	281.00
IUUC-Mdo-062735	Monodelphis domestica	46.44	1.00e-77	281.00
IUUC-Mmu-063263	Mus musculus	46.78	4.00e-77	279.00
IUUC-Mac-065323	Musa acuminata	48.75	8.00e-75	271.00
IUUC-Mpu-066038	Mustela putorius furo	44.71	6.00e-74	269.00
IUUC-Mlu-068128	Myotis lucifugus	46.44	7.00e-78	281.00
IUUC-Nfi-068611	Neosartorya fischeri	44.02	2.00e-102	364.00
IUUC-Ncr-068699	Neurospora crassa	43.52	9.00e-103	365.00
IUUC-Nle-069767	Nomascus leucogenys	46.10	4.00e-77	279.00
IUUC-Opr-070980	Ochotona princeps	44.71	2.00e-73	266.00
IUUC-Ont-072658	Oreochromis niloticus	46.46	3.00e-78	283.00
IUUC-Oan-073372	Ornithorhynchus anatinus	46.44	6.00e-77	278.00
IUUC-Ocu-074322	Oryctolagus cuniculus	46.10	1.00e-76	278.00
IUUC-Oba-075220	Oryza barthii	42.99	3.00e-70	256.00
IUUC-Obr-076208	Oryza brachyantha	45.15	3.00e-68	249.00
IUUC-Ogl-077216	Oryza glaberrima	42.99	3.00e-70	256.00
IUUC-Ogu-078836	Oryza glumaepatula	42.99	3.00e-70	256.00
IUUC-Oin-079522	Oryza indica	42.99	3.00e-70	256.00
IUUC-Olo-080882	Oryza longistaminata	42.99	3.00e-70	256.00
IUUC-Ome-081549	Oryza meridionalis	42.99	3.00e-70	256.00
IUUC-Oni-082982	Oryza nivara	42.99	3.00e-70	256.00
IUUC-Opu-084002	Oryza punctata	45.48	5.00e-69	252.00
IUUC-Oru-084568	Oryza rufipogon	42.99	3.00e-70	256.00
IUUC-Osa-085299	Oryza sativa	42.99	3.00e-70	256.00
IUUC-Ola-087418	Oryzias latipes	46.46	2.00e-78	283.00
IUUC-Olu-087809	Ostreococcus lucimarinus	44.44	4.00e-54	202.00
IUUC-Oga-088298	Otolemur garnettii	46.44	1.00e-77	281.00
IUUC-Oar-090269	Ovis aries	46.60	1.00e-76	278.00
IUUC-Ptr-090467	Pan troglodytes	46.10	3.00e-77	279.00
IUUC-Pan-091753	Papio anubis	44.71	9.00e-74	268.00
IUUC-Psi-092993	Pelodiscus sinensis	46.10	1.00e-77	280.00
IUUC-Pma-094388	Petromyzon marinus	45.00	1.00e-74	271.00
IUUC-Pno-095044	Phaeosphaeria nodorum	39.34	4.00e-93	333.00
IUUC-Ppa-095415	Physcomitrella patens	45.93	3.00e-76	276.00
IUUC-Pfo-097052	Poecilia formosa	46.46	2.00e-78	283.00
IUUC-Pab-097797	Pongo abelii	46.10	3.00e-77	279.00
IUUC-Pop-099016	Populus trichocarpa	46.33	2.00e-72	264.00
IUUC-Pca-100835	Procavia capensis	49.79	2.00e-64	237.00
IUUC-Ppe-101474	Prunus persica	45.63	8.00e-75	271.00
IUUC-Pva-102878	Pteropus vampyrus	46.08	8.00e-76	275.00
IUUC-Pgr-103306	Puccinia graminis	50.48	2.00e-87	315.00
IUUC-Pte-104356	Pyrenophora teres	43.28	2.00e-98	352.00
IUUC-Pyt-104709	Pyrenophora triticirepentis	51.28	1.00e-91	328.00
IUUC-Rno-106060	Rattus norvegicus	45.76	1.00e-76	277.00
IUUC-Sce-106367	Saccharomyces cerevisiae	40.78	2.00e-65	241.00
IUUC-Sha-107087	Sarcophilus harrisii	46.44	7.00e-78	281.00
IUUC-Sja-107684	Schizosaccharomyces japonicus	57.32	7.00e-147	511.00
IUUC-Smo-109064	Selaginella moellendorffii	47.68	1.00e-70	258.00
IUUC-Sit-110819	Setaria italica	43.45	8.00e-73	265.00
IUUC-Sly-111210	Solanum lycopersicum	46.10	2.00e-73	267.00
IUUC-Stu-112398	Solanum tuberosum	44.97	5.00e-71	259.00
IUUC-Sar-113216	Sorex araneus	46.44	4.00e-76	276.00
IUUC-Sbi-114724	Sorghum bicolor	44.12	1.00e-72	264.00
IUUC-Sre-115197	Sporisorium reilianum	52.16	2.00e-80	291.00
IUUC-Ssc-116321	Sus scrofa	46.96	1.00e-77	281.00
IUUC-Tgu-117482	Taeniopygia guttata	45.92	1.00e-75	274.00
IUUC-Tru-118613	Takifugu rubripes	46.46	3.00e-78	283.00
IUUC-Tsy-119520	Tarsius syrichta	51.03	9.00e-54	201.00
IUUC-Tni-120293	Tetraodon nigroviridis	46.46	3.00e-78	283.00
IUUC-Tca-121329	Theobroma cacao	44.81	6.00e-73	265.00
IUUC-Tre-122226	Trichoderma reesei	41.88	1.00e-96	345.00
IUUC-Tvi-122330	Trichoderma virens	51.60	5.00e-96	343.00
IUUC-Tae-125280	Triticum aestivum	44.05	1.00e-71	261.00
IUUC-Tur-126563	Triticum urartu	44.05	2.00e-71	260.00
IUUC-Tme-126890	Tuber melanosporum	50.80	3.00e-95	340.00
IUUC-Tbe-127783	Tupaia belangeri	46.44	8.00e-78	281.00
IUUC-Ttr-129083	Tursiops truncatus	46.10	3.00e-77	279.00
IUUC-Uma-129409	Ustilago maydis	52.67	1.00e-80	293.00
IUUC-Vda-129736	Verticillium dahliae	33.27	3.00e-74	271.00
IUUC-Vpa-130391	Vicugna pacos	44.22	4.00e-70	256.00
IUUC-Vvi-131371	Vitis vinifera	45.93	1.00e-73	268.00
IUUC-Xtr-132464	Xenopus tropicalis	45.95	1.00e-75	274.00
IUUC-Xma-133475	Xiphophorus maculatus	46.46	2.00e-78	283.00
IUUC-Yli-134632	Yarrowia lipolytica	55.79	1.00e-94	339.00
IUUC-Zma-134951	Zea mays	44.12	9.00e-73	265.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence