iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000018057.2	ENSSSCT00000019652.2	ENSSSCP00000019132.2
ENSSSCG00000018057.2	ENSSSCT00000028920.1	ENSSSCP00000023078.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.80e-14	53.6	505	552

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           +++ +++s++ SLqhLCR++Ir++++++++   + LPLPk L++Y++++ y
   Q: 505  LYPVSRFSNVKSLQHLCRFRIRQLVRIDHI---PDLPLPKPLISYIRKFYY 552
           567899*********************998...*************99976 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MVFRNVGRPP EEEDAEAAPD PGPSELLCPR HRCALDPKAL PPGLALERTW GPAAGLEAQL 60
AALGLGQSAG PGVKTVSGGC CPCPCPPQPP PPQPQPPAAA PQAGEDPTET SDALLVLEGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGGCCGCC GCAGCTGATG GTGTTCCGCA ACGTGGGTCG GCCGCCGGAG GAGGAGGACG 60
CGGAGGCGGC CCCGGATCCG GGACCCTCAG AACTGCTGTG TCCCCGGCAC CGCTGTGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028423--SOCS7
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0008286--P:insulin receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0021819--P:layer formation in cerebral cortex
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination
GO:0021942--P:radial glia guided migration of Purkinje cell

KEGG

ssc:100514187

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001668	Ailuropoda melanoleuca	90.79	0.00e+00	653.00
IUUC-Apl-003277	Anas platyrhynchos	91.10	1.00e-72	264.00
IUUC-Aca-004639	Anolis carolinensis	98.32	3.00e-107	380.00
IUUC-Ame-011301	Astyanax mexicanus	71.20	4.00e-132	464.00
IUUC-Bta-013483	Bos taurus	96.56	0.00e+00	744.00
IUUC-Cja-019765	Callithrix jacchus	99.06	6.00e-162	562.00
IUUC-Cfa-020109	Canis familiaris	97.88	0.00e+00	644.00
IUUC-Cpo-021555	Cavia porcellus	95.50	5.00e-177	613.00
IUUC-Csa-023580	Chlorocebus sabaeus	96.91	0.00e+00	710.00
IUUC-Cho-024431	Choloepus hoffmanni	100.00	3.00e-71	261.00
IUUC-Dno-028858	Dasypus novemcinctus	94.32	0.00e+00	714.00
IUUC-Dor-031071	Dipodomys ordii	78.68	3.00e-112	397.00
IUUC-Dme-031876	Drosophila melanogaster	43.65	2.00e-43	170.00
IUUC-Ete-032928	Echinops telfairi	71.47	6.00e-102	364.00
IUUC-Eca-033250	Equus caballus	93.18	4.00e-175	607.00
IUUC-Eeu-034946	Erinaceus europaeus	85.17	6.00e-52	197.00
IUUC-Fca-036589	Felis catus	94.98	0.00e+00	639.00
IUUC-Fal-037316	Ficedula albicollis	92.12	1.00e-110	391.00
IUUC-Gmo-038552	Gadus morhua	91.26	7.00e-54	201.00
IUUC-Gga-041248	Gallus gallus	97.22	2.00e-106	377.00
IUUC-Gac-041469	Gasterosteus aculeatus	83.47	6.00e-57	212.00
IUUC-Ggo-045282	Gorilla gorilla	98.75	4.00e-161	560.00
IUUC-Hsa-045926	Homo sapiens	97.08	0.00e+00	712.00
IUUC-Itr-048411	Ictidomys tridecemlineatus	94.95	3.00e-164	571.00
IUUC-Lch-049768	Latimeria chalumnae	72.28	7.00e-155	540.00
IUUC-Loc-051949	Lepisosteus oculatus	69.09	2.00e-128	452.00
IUUC-Laf-053410	Loxodonta africana	92.91	0.00e+00	708.00
IUUC-Mcc-054605	Macaca mulatta	90.27	0.00e+00	685.00
IUUC-Meu-056773	Macropus eugenii	79.62	3.00e-105	374.00
IUUC-Mmr-060927	Microcebus murinus	96.35	0.00e+00	707.00
IUUC-Mdo-061892	Monodelphis domestica	88.17	2.00e-174	605.00
IUUC-Mmu-064246	Mus musculus	93.30	0.00e+00	711.00
IUUC-Mpu-065995	Mustela putorius furo	95.39	0.00e+00	632.00
IUUC-Mlu-067526	Myotis lucifugus	93.63	0.00e+00	720.00
IUUC-Nle-069317	Nomascus leucogenys	91.65	2.00e-167	582.00
IUUC-Ont-072258	Oreochromis niloticus	83.66	4.00e-105	375.00
IUUC-Oan-073703	Ornithorhynchus anatinus	80.49	7.00e-37	144.00
IUUC-Ocu-074577	Oryctolagus cuniculus	88.93	0.00e+00	730.00
IUUC-Oga-088426	Otolemur garnettii	94.66	0.00e+00	697.00
IUUC-Oar-089407	Ovis aries	96.86	0.00e+00	669.00
IUUC-Ptr-091327	Pan troglodytes	97.88	0.00e+00	627.00
IUUC-Pan-092064	Papio anubis	98.14	0.00e+00	639.00
IUUC-Psi-093834	Pelodiscus sinensis	93.75	4.00e-152	530.00
IUUC-Pfo-097100	Poecilia formosa	62.63	3.00e-115	409.00
IUUC-Pab-097695	Pongo abelii	88.30	0.00e+00	681.00
IUUC-Pca-100569	Procavia capensis	89.89	6.00e-169	587.00
IUUC-Pva-102784	Pteropus vampyrus	95.01	0.00e+00	703.00
IUUC-Ptt-103775	Puccinia triticina	38.46	1.50e+00	28.10
IUUC-Rno-105485	Rattus norvegicus	94.15	0.00e+00	711.00
IUUC-Sha-106720	Sarcophilus harrisii	93.16	1.00e-170	592.00
IUUC-Smo-109349	Selaginella moellendorffii	42.42	1.10e+00	28.50
IUUC-Sar-112975	Sorex araneus	84.01	2.00e-126	444.00
IUUC-Tgu-116867	Taeniopygia guttata	87.26	5.00e-124	436.00
IUUC-Tru-117562	Takifugu rubripes	81.11	4.00e-101	361.00
IUUC-Tsy-118999	Tarsius syrichta	93.10	6.00e-145	506.00
IUUC-Tni-120793	Tetraodon nigroviridis	68.19	1.00e-127	449.00
IUUC-Tbe-127671	Tupaia belangeri	98.16	3.00e-127	447.00
IUUC-Ttr-128491	Tursiops truncatus	82.77	1.00e-132	466.00
IUUC-Vpa-130104	Vicugna pacos	90.14	1.00e-177	616.00
IUUC-Xtr-132507	Xenopus tropicalis	81.72	8.00e-145	506.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence