iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037008

Ensembl Protein ID

ENSFALP00000002369.1

UniProt Accession

U3JHW5; U3JHW5_FICAL

Genbank Protein ID

ENSFALP00000002369

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011150

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000002277.1	ENSFALT00000002381.1	ENSFALP00000002369.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.60e-08	33.2	69	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ f+  p+++pCgH f+a+Cl   w       s+ f+CP Cr
   Q: 69   CSICLCLFSS-PVTVPCGHNFCASCLeLTW----AGLSGGFSCPQCR 110
           ********99.9******************....99**********8 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MGGRRRVRPP AAAPPVGAGM ERAVFRKASA SFVSPSAGSF LAVEAAADGA MAALESEPGL 60
SGLEEELTCS ICLCLFSSPV TVPCGHNFCA SCLELTWAGL SGGFSCPQCR ATFAGRPQLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGCCCCGCC CCGGGGTCCC GTTCCCAGGG CAGAGCCCCC AGCACCCCGG CGCTGCCCGG 60
CCCCCGACAT GGGCGGGCGC CGCAGGGTTC GTCCCCCGGC TGCCGCCCCT CCCGTCGGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	48.25	5.00e-168	584.00
IUUC-Apl-004101	Anas platyrhynchos	66.19	0.00e+00	799.00
IUUC-Aca-005025	Anolis carolinensis	50.31	0.00e+00	627.00
IUUC-Ame-011962	Astyanax mexicanus	28.96	2.00e-33	136.00
IUUC-Bta-012735	Bos taurus	46.90	2.00e-167	582.00
IUUC-Cja-019996	Callithrix jacchus	46.33	1.00e-86	313.00
IUUC-Cfa-020466	Canis familiaris	46.78	3.00e-166	578.00
IUUC-Cpo-021737	Cavia porcellus	46.67	2.00e-162	565.00
IUUC-Csa-023217	Chlorocebus sabaeus	45.41	1.00e-161	563.00
IUUC-Cho-024346	Choloepus hoffmanni	36.67	1.00e-42	166.00
IUUC-Dre-028781	Danio rerio	26.82	2.00e-63	236.00
IUUC-Dno-030082	Dasypus novemcinctus	49.06	2.00e-169	588.00
IUUC-Dor-030335	Dipodomys ordii	33.46	6.00e-64	238.00
IUUC-Ete-032923	Echinops telfairi	45.47	6.00e-145	507.00
IUUC-Eca-033411	Equus caballus	47.97	8.00e-168	583.00
IUUC-Eeu-034656	Erinaceus europaeus	46.81	7.00e-88	317.00
IUUC-Fca-035371	Felis catus	47.61	2.00e-167	582.00
IUUC-Gmo-038668	Gadus morhua	34.07	1.00e-101	363.00
IUUC-Gga-040608	Gallus gallus	66.19	0.00e+00	785.00
IUUC-Gac-041409	Gasterosteus aculeatus	35.33	6.00e-109	387.00
IUUC-Ggo-044518	Gorilla gorilla	44.58	1.00e-158	553.00
IUUC-Hsa-045828	Homo sapiens	44.67	6.00e-160	557.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	44.28	4.00e-147	514.00
IUUC-Lch-050478	Latimeria chalumnae	40.38	1.00e-75	277.00
IUUC-Loc-052864	Lepisosteus oculatus	38.69	1.00e-111	396.00
IUUC-Laf-054325	Loxodonta africana	49.31	5.00e-97	347.00
IUUC-Mcc-054920	Macaca mulatta	45.64	1.00e-161	562.00
IUUC-Meu-056367	Macropus eugenii	57.95	2.00e-59	223.00
IUUC-Mor-057142	Magnaporthe oryzae	50.00	6.00e-05	42.00
IUUC-Mga-059975	Meleagris gallopavo	63.91	0.00e+00	768.00
IUUC-Mmr-060748	Microcebus murinus	46.22	8.00e-163	566.00
IUUC-Mdo-062904	Monodelphis domestica	46.95	1.00e-155	543.00
IUUC-Mmu-063891	Mus musculus	46.28	6.00e-163	567.00
IUUC-Mpu-066473	Mustela putorius furo	46.64	5.00e-167	580.00
IUUC-Mlu-068185	Myotis lucifugus	47.47	3.00e-163	568.00
IUUC-Nle-070177	Nomascus leucogenys	45.16	1.00e-160	559.00
IUUC-Opr-070558	Ochotona princeps	44.38	1.00e-83	303.00
IUUC-Ont-072043	Oreochromis niloticus	26.22	8.00e-60	224.00
IUUC-Oan-072819	Ornithorhynchus anatinus	34.10	2.00e-24	105.00
IUUC-Ocu-074461	Oryctolagus cuniculus	48.46	5.00e-92	331.00
IUUC-Ola-087180	Oryzias latipes	29.28	1.00e-57	217.00
IUUC-Oga-088937	Otolemur garnettii	46.23	7.00e-157	547.00
IUUC-Oar-089781	Ovis aries	45.08	2.00e-107	382.00
IUUC-Ptr-090771	Pan troglodytes	44.55	4.00e-159	554.00
IUUC-Pan-092830	Papio anubis	45.41	2.00e-161	562.00
IUUC-Psi-093664	Pelodiscus sinensis	58.51	0.00e+00	699.00
IUUC-Pma-094147	Petromyzon marinus	26.61	2.00e-52	200.00
IUUC-Pfo-096906	Poecilia formosa	26.58	4.00e-64	238.00
IUUC-Pab-097588	Pongo abelii	45.33	6.00e-159	553.00
IUUC-Pca-100890	Procavia capensis	47.61	3.00e-89	322.00
IUUC-Pva-102314	Pteropus vampyrus	47.14	8.00e-160	556.00
IUUC-Rno-105234	Rattus norvegicus	47.06	8.00e-88	317.00
IUUC-Sha-106807	Sarcophilus harrisii	44.74	1.00e-154	539.00
IUUC-Sar-113283	Sorex araneus	45.43	5.00e-75	274.00
IUUC-Ssc-115878	Sus scrofa	50.00	9.00e-60	223.00
IUUC-Tgu-117026	Taeniopygia guttata	72.66	0.00e+00	744.00
IUUC-Tru-117794	Takifugu rubripes	36.56	4.00e-55	209.00
IUUC-Tni-120550	Tetraodon nigroviridis	27.17	2.00e-64	239.00
IUUC-Tbe-127580	Tupaia belangeri	45.28	4.00e-76	278.00
IUUC-Ttr-128648	Tursiops truncatus	58.79	2.00e-73	269.00
IUUC-Vpa-130254	Vicugna pacos	63.37	6.00e-70	257.00
IUUC-Xtr-132892	Xenopus tropicalis	44.13	6.00e-80	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence