iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044691

UUCD1 version

UUC-GoG-00793

Ensembl Protein ID

ENSGGOP00000020849.1

UniProt Accession

G3RYG1; G3RYG1_GORGO

Protein Name

Uncharacterized protein

Gene Name

RC3H1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000005735.2	ENSGGOT00000024462.1	ENSGGOP00000020849.1
ENSGGOG00000005735.2	ENSGGOT00000005769.2	ENSGGOP00000005623.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	93.33	0.00e+00	1914.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPITLCSGV EDTKHYEEAK KCVEELALYL KPLSSARGVG 120

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Nucleotide Sequence
(Fasta)

ATGCCTGTAC AAGCTCCACA ATGGACGGAT TTCCTCTCCT GCCCAATTTG CACTCAGACT 60
TTCGACGAAA CAATTCGAAA GCCCATCAGT TTGGGTTGTG GCCATACTGT CTGCAAGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	90.69	0.00e+00	1791.00
IUUC-Apl-003290	Anas platyrhynchos	81.49	0.00e+00	1696.00
IUUC-Aca-004905	Anolis carolinensis	80.45	0.00e+00	1623.00
IUUC-Ame-011475	Astyanax mexicanus	61.46	0.00e+00	1127.00
IUUC-Cja-019907	Callithrix jacchus	92.28	0.00e+00	1890.00
IUUC-Cfa-020679	Canis familiaris	90.43	0.00e+00	1788.00
IUUC-Cpo-022110	Cavia porcellus	85.99	0.00e+00	1783.00
IUUC-Csa-024166	Chlorocebus sabaeus	92.40	0.00e+00	1820.00
IUUC-Dno-029870	Dasypus novemcinctus	88.66	0.00e+00	880.00
IUUC-Dor-030934	Dipodomys ordii	83.55	0.00e+00	1393.00
IUUC-Dme-031708	Drosophila melanogaster	64.51	9.00e-163	567.00
IUUC-Ete-032652	Echinops telfairi	91.40	0.00e+00	1292.00
IUUC-Eca-033236	Equus caballus	90.17	0.00e+00	1758.00
IUUC-Eeu-035091	Erinaceus europaeus	83.30	0.00e+00	878.00
IUUC-Fca-035773	Felis catus	90.78	0.00e+00	1796.00
IUUC-Fal-036972	Ficedula albicollis	80.97	0.00e+00	1696.00
IUUC-Gmo-039303	Gadus morhua	80.24	0.00e+00	895.00
IUUC-Hsa-046163	Homo sapiens	93.33	0.00e+00	1915.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	83.31	0.00e+00	889.00
IUUC-Lch-050667	Latimeria chalumnae	70.38	0.00e+00	1421.00
IUUC-Loc-052404	Lepisosteus oculatus	66.02	0.00e+00	1232.00
IUUC-Laf-053618	Loxodonta africana	90.94	0.00e+00	1742.00
IUUC-Mcc-054692	Macaca mulatta	92.71	0.00e+00	1905.00
IUUC-Meu-056025	Macropus eugenii	77.62	0.00e+00	791.00
IUUC-Mmr-061188	Microcebus murinus	91.13	0.00e+00	1795.00
IUUC-Mdo-063035	Monodelphis domestica	86.58	0.00e+00	1731.00
IUUC-Mmu-064146	Mus musculus	87.01	0.00e+00	1783.00
IUUC-Mpu-066217	Mustela putorius furo	89.90	0.00e+00	1768.00
IUUC-Mlu-068023	Myotis lucifugus	89.64	0.00e+00	1793.00
IUUC-Nle-069506	Nomascus leucogenys	92.98	0.00e+00	1907.00
IUUC-Opr-070587	Ochotona princeps	77.09	0.00e+00	1434.00
IUUC-Ont-071278	Oreochromis niloticus	60.20	0.00e+00	1120.00
IUUC-Oan-073500	Ornithorhynchus anatinus	85.99	0.00e+00	1802.00
IUUC-Ocu-074299	Oryctolagus cuniculus	89.61	0.00e+00	1675.00
IUUC-Ola-086665	Oryzias latipes	58.97	0.00e+00	1138.00
IUUC-Oga-088519	Otolemur garnettii	83.79	0.00e+00	1579.00
IUUC-Oar-089246	Ovis aries	90.30	0.00e+00	1675.00
IUUC-Ptr-091102	Pan troglodytes	93.42	0.00e+00	1916.00
IUUC-Pan-091952	Papio anubis	92.98	0.00e+00	1915.00
IUUC-Pfo-097227	Poecilia formosa	59.68	0.00e+00	1105.00
IUUC-Pab-097975	Pongo abelii	92.19	0.00e+00	1878.00
IUUC-Pca-101127	Procavia capensis	85.91	0.00e+00	1197.00
IUUC-Pva-102431	Pteropus vampyrus	82.00	0.00e+00	1580.00
IUUC-Sha-106690	Sarcophilus harrisii	85.98	0.00e+00	1756.00
IUUC-Ssc-116189	Sus scrofa	90.96	0.00e+00	1737.00
IUUC-Tgu-116527	Taeniopygia guttata	81.94	0.00e+00	1707.00
IUUC-Tru-118389	Takifugu rubripes	59.48	0.00e+00	1139.00
IUUC-Tsy-119193	Tarsius syrichta	88.53	0.00e+00	1756.00
IUUC-Tni-119790	Tetraodon nigroviridis	61.75	0.00e+00	1050.00
IUUC-Tbe-127445	Tupaia belangeri	96.73	0.00e+00	1314.00
IUUC-Ttr-128877	Tursiops truncatus	90.27	0.00e+00	1725.00
IUUC-Xtr-132274	Xenopus tropicalis	74.98	0.00e+00	1498.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence