iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000000490.2	ENSPPYT00000033552.1	ENSPPYP00000024290.1
ENSPPYG00000000490.2	ENSPPYT00000000589.1	ENSPPYP00000000565.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	96.03	0.00e+00	1979.00	IUUC-Hsa-046163

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pongo abelii

Protein Sequence
(Fasta)

MPVQAPQWTD FLSCPICTQT FDETIRKPIS LGCGHTVCKM CLNKLHRKAC PFDQTTINTD 60
IELLPVNSAL LQLVGAQVPE QQPITLCSGV EDTKHYEEAK KCVEELALYL KPLSSARGVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGTATCTA CAGAAGATAT TTAAAAAAAA AAGATAAACT TTTTTTCAAA GATTTTGATT 60
CCAGTGGAAT CTTTGCTTTA GATTTGTGTG TGTGTTTGTG TTCGTGAATT GTAACTCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR032671--RC3H1
IPR027370--Znf-RING_LisH
IPR000571--Znf_CCCH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50103--ZF_C3H1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00642--zf-CCCH
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00356--ZnF_C3H1

Gene Ontology

GO:0010494--C:cytoplasmic stress granule
GO:0000932--C:P-body
GO:0003730--F:mRNA 3'-UTR binding
GO:0035613--F:RNA stem-loop binding
GO:0008270--F:zinc ion binding
GO:0061158--P:3'-UTR-mediated mRNA destabilization
GO:0001782--P:B cell homeostasis
GO:0071347--P:cellular response to interleukin-1
GO:0033962--P:cytoplasmic mRNA processing body assembly
GO:0048535--P:lymph node development
GO:0046007--P:negative regulation of activated T cell proliferation
GO:0030889--P:negative regulation of B cell proliferation
GO:0002635--P:negative regulation of germinal center formation
GO:0045623--P:negative regulation of T-helper cell differentiation
GO:0000288--P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0061014--P:positive regulation of mRNA catabolic process
GO:1901224--P:positive regulation of NIK/NF-kappaB signaling
GO:0050856--P:regulation of T cell receptor signaling pathway
GO:0048536--P:spleen development
GO:0043029--P:T cell homeostasis
GO:0042098--P:T cell proliferation
GO:0061470--P:T follicular helper cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001700	Ailuropoda melanoleuca	93.56	0.00e+00	1877.00
IUUC-Apl-003290	Anas platyrhynchos	84.38	0.00e+00	1775.00
IUUC-Aca-004905	Anolis carolinensis	83.29	0.00e+00	1704.00
IUUC-Ame-011475	Astyanax mexicanus	65.20	0.00e+00	1194.00
IUUC-Cja-019907	Callithrix jacchus	95.15	0.00e+00	1966.00
IUUC-Cfa-020679	Canis familiaris	93.56	0.00e+00	1866.00
IUUC-Cpo-022110	Cavia porcellus	89.17	0.00e+00	1868.00
IUUC-Csa-024166	Chlorocebus sabaeus	97.21	0.00e+00	1919.00
IUUC-Dno-029870	Dasypus novemcinctus	95.34	0.00e+00	982.00
IUUC-Dor-030934	Dipodomys ordii	87.54	0.00e+00	1496.00
IUUC-Dme-031708	Drosophila melanogaster	64.51	1.00e-162	566.00
IUUC-Ete-032652	Echinops telfairi	95.93	0.00e+00	1387.00
IUUC-Eca-033236	Equus caballus	93.12	0.00e+00	1833.00
IUUC-Eeu-035091	Erinaceus europaeus	83.30	0.00e+00	876.00
IUUC-Fca-035773	Felis catus	93.92	0.00e+00	1870.00
IUUC-Fal-036972	Ficedula albicollis	84.45	0.00e+00	1781.00
IUUC-Gmo-039303	Gadus morhua	80.24	0.00e+00	893.00
IUUC-Ggo-044691	Gorilla gorilla	92.19	0.00e+00	1880.00
IUUC-Hsa-046163	Homo sapiens	96.03	0.00e+00	1980.00
IUUC-Itr-048266	Ictidomys tridecemlineatus	88.78	0.00e+00	966.00
IUUC-Lch-050667	Latimeria chalumnae	72.93	0.00e+00	1483.00
IUUC-Loc-052404	Lepisosteus oculatus	70.00	0.00e+00	1291.00
IUUC-Laf-053618	Loxodonta africana	94.08	0.00e+00	1820.00
IUUC-Mcc-054692	Macaca mulatta	95.76	0.00e+00	1981.00
IUUC-Meu-056025	Macropus eugenii	82.85	0.00e+00	889.00
IUUC-Mmr-061188	Microcebus murinus	94.17	0.00e+00	1875.00
IUUC-Mdo-063035	Monodelphis domestica	89.51	0.00e+00	1819.00
IUUC-Mmu-064146	Mus musculus	89.76	0.00e+00	1856.00
IUUC-Mpu-066217	Mustela putorius furo	92.94	0.00e+00	1845.00
IUUC-Mlu-068023	Myotis lucifugus	92.32	0.00e+00	1865.00
IUUC-Nle-069506	Nomascus leucogenys	95.94	0.00e+00	1982.00
IUUC-Opr-070587	Ochotona princeps	80.37	0.00e+00	1519.00
IUUC-Ont-071278	Oreochromis niloticus	61.86	0.00e+00	1164.00
IUUC-Oan-073500	Ornithorhynchus anatinus	88.56	0.00e+00	1883.00
IUUC-Ocu-074299	Oryctolagus cuniculus	92.84	0.00e+00	1754.00
IUUC-Ola-086665	Oryzias latipes	60.84	0.00e+00	1184.00
IUUC-Oga-088519	Otolemur garnettii	86.96	0.00e+00	1676.00
IUUC-Oar-089246	Ovis aries	93.07	0.00e+00	1754.00
IUUC-Ptr-091102	Pan troglodytes	96.12	0.00e+00	1983.00
IUUC-Pan-091952	Papio anubis	95.68	0.00e+00	1977.00
IUUC-Pfo-097227	Poecilia formosa	61.03	0.00e+00	1142.00
IUUC-Pca-101127	Procavia capensis	86.97	0.00e+00	1219.00
IUUC-Pva-102431	Pteropus vampyrus	84.82	0.00e+00	1650.00
IUUC-Sha-106690	Sarcophilus harrisii	88.46	0.00e+00	1842.00
IUUC-Ssc-116189	Sus scrofa	93.92	0.00e+00	1812.00
IUUC-Tgu-116527	Taeniopygia guttata	85.00	0.00e+00	1785.00
IUUC-Tru-118389	Takifugu rubripes	61.19	0.00e+00	1192.00
IUUC-Tsy-119193	Tarsius syrichta	92.14	0.00e+00	1842.00
IUUC-Tni-119790	Tetraodon nigroviridis	64.41	0.00e+00	1123.00
IUUC-Tbe-127445	Tupaia belangeri	90.91	0.00e+00	1536.00
IUUC-Ttr-128877	Tursiops truncatus	93.22	0.00e+00	1801.00
IUUC-Xtr-132274	Xenopus tropicalis	77.33	0.00e+00	1566.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence