iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA
Protein-protein Interaction
IID	iRefIndex	PINA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.10e-06	27.9	21	133

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr............................................................. 41
           C+iC++ +++ p+ ++CgH+ + +C+ +++++ +  +                                                                 
   Q: 21   CPICYNIYDK-PMQMGCGHTLCSTCIGRLVDQVKTNM---Aeelgrprgpllhpddigpgfgglggfadqedqphfidlprldprmnpndpnmvrgivvlpr 118
           ********99.***************77722222111...12334444555555555555555555555555566666666666666666666666666666 PP
   S: 42   ...........CPlC 45
                      CP C
   Q: 119  rgpearateikCPEC 133
           666666666666666 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MDIPGTSGTS NYQQWAHVVE CPICYNIYDK PMQMGCGHTL CSTCIGRLVD QVKTNMAEEL 60
GRPRGPLLHP DDIGPGFGGL GGFADQEDQP HFIDLPRLDP RMNPNDPNMV RGIVVLPRRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCCGCCTG ACGGGCAAAT CGGGTTCAAA ACCGATTATT CACATTTTTA TTGGAATATT 60
TGAATATATT TTTGTATAAA TAAAAAGCAA TAATGGACAT TCCGGGCACA AGTGGTACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0043073--C:germ cell nucleus
GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0007059--P:chromosome segregation
GO:0040027--P:negative regulation of vulval development
GO:0045815--P:positive regulation of gene expression, epigenetic
GO:0000003--P:reproduction

KEGG

cel:CELE_F26G5.9

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002394	Ailuropoda melanoleuca	48.72	5.00e-09	55.80
IUUC-Apl-004222	Anas platyrhynchos	48.72	5.00e-09	55.80
IUUC-Aca-004905	Anolis carolinensis	43.59	1.00e-07	51.20
IUUC-Bta-012366	Bos taurus	48.72	5.00e-09	55.80
IUUC-Cja-019462	Callithrix jacchus	48.72	5.00e-09	55.80
IUUC-Cfa-020679	Canis familiaris	38.60	8.00e-08	52.00
IUUC-Cpo-021406	Cavia porcellus	48.72	5.00e-09	56.20
IUUC-Cho-024281	Choloepus hoffmanni	43.59	5.00e-08	52.80
IUUC-Dre-028035	Danio rerio	48.72	2.00e-08	53.90
IUUC-Dno-029311	Dasypus novemcinctus	48.72	5.00e-09	55.80
IUUC-Dor-030104	Dipodomys ordii	48.72	5.00e-09	56.20
IUUC-Ete-032926	Echinops telfairi	48.72	5.00e-09	55.80
IUUC-Eca-034318	Equus caballus	48.72	5.00e-09	55.80
IUUC-Eeu-035091	Erinaceus europaeus	38.60	1.00e-07	51.20
IUUC-Fca-035557	Felis catus	48.72	5.00e-09	55.80
IUUC-Fal-037375	Ficedula albicollis	48.72	5.00e-09	55.80
IUUC-Gga-040314	Gallus gallus	48.72	5.00e-09	55.80
IUUC-Ggo-045647	Gorilla gorilla	48.72	5.00e-09	55.80
IUUC-Hsa-046662	Homo sapiens	48.72	5.00e-09	55.80
IUUC-Loc-052585	Lepisosteus oculatus	46.15	2.00e-08	53.90
IUUC-Laf-054151	Loxodonta africana	48.72	4.00e-09	56.20
IUUC-Mcc-055136	Macaca mulatta	48.72	5.00e-09	55.80
IUUC-Meu-056747	Macropus eugenii	48.72	9.00e-09	55.10
IUUC-Mga-060133	Meleagris gallopavo	48.72	5.00e-09	55.80
IUUC-Mmr-061559	Microcebus murinus	48.72	5.00e-09	55.80
IUUC-Mdo-061870	Monodelphis domestica	48.72	6.00e-09	55.80
IUUC-Mmu-063500	Mus musculus	48.72	5.00e-09	56.20
IUUC-Mpu-066281	Mustela putorius furo	48.72	5.00e-09	55.80
IUUC-Mlu-067576	Myotis lucifugus	48.72	5.00e-09	55.80
IUUC-Nle-069921	Nomascus leucogenys	48.72	5.00e-09	55.80
IUUC-Opr-070587	Ochotona princeps	38.60	8.00e-08	51.60
IUUC-Ont-071268	Oreochromis niloticus	46.15	5.00e-08	52.40
IUUC-Oan-073576	Ornithorhynchus anatinus	48.72	5.00e-09	55.80
IUUC-Ocu-073971	Oryctolagus cuniculus	48.72	5.00e-09	56.20
IUUC-Oga-088315	Otolemur garnettii	48.72	5.00e-09	55.80
IUUC-Oar-090393	Ovis aries	48.72	5.00e-09	56.20
IUUC-Ptr-091666	Pan troglodytes	48.72	5.00e-09	55.80
IUUC-Pan-091952	Papio anubis	38.60	8.00e-08	51.60
IUUC-Psi-093944	Pelodiscus sinensis	48.72	5.00e-09	55.80
IUUC-Pfo-097469	Poecilia formosa	46.15	4.00e-08	52.80
IUUC-Pab-098468	Pongo abelii	48.72	4.00e-09	56.20
IUUC-Pca-100792	Procavia capensis	48.72	6.00e-09	55.80
IUUC-Pva-103070	Pteropus vampyrus	48.72	5.00e-09	55.80
IUUC-Rno-105194	Rattus norvegicus	48.72	4.00e-09	56.20
IUUC-Sha-106725	Sarcophilus harrisii	48.72	4.00e-09	56.20
IUUC-Sar-112923	Sorex araneus	48.72	5.00e-09	55.80
IUUC-Ssc-115411	Sus scrofa	48.72	4.00e-09	56.20
IUUC-Tgu-116794	Taeniopygia guttata	48.72	5.00e-09	55.80
IUUC-Tru-118270	Takifugu rubripes	46.15	7.00e-08	51.60
IUUC-Tsy-119636	Tarsius syrichta	48.72	5.00e-09	55.80
IUUC-Tbe-127317	Tupaia belangeri	48.72	4.00e-09	55.80
IUUC-Ttr-129141	Tursiops truncatus	48.72	5.00e-09	55.80
IUUC-Vpa-130204	Vicugna pacos	48.72	6.00e-09	55.80
IUUC-Xtr-132274	Xenopus tropicalis	38.60	8.00e-08	52.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence