iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gac-041762

Ensembl Protein ID

ENSGACP00000026214.1

UniProt Accession

G3Q8K0; G3Q8K0_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000019839.1	ENSGACT00000026265.1	ENSGACP00000026214.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-40	134.1	1131	1168
UBD/Beta-Prp	1.10e-72	245.2	614	809

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH d v++++f  d ++l++G d+g i++W++ +g+ll
   Q: 1131 GHRDCVRSCRFsWDgRRLATGDDNGEIRLWSVMEGTLL 1168
           8********9995559****************999877 PP

UBD/Beta-Prp

   S: 91   kghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
           + h+ s++s  fs++g k++s ++ ++++v++  +g++l    + hd+ v c +++pd++ll+++s Dr+v++W+++++ llr ++++h
   Q: 614  HPHQGSIYSACFSQDGAKIASSGASKMLKVFKSTSGEKLM-EIQAHDDEVLCCAFSPDDRLLATCSSDRKVKVWNVERAMLLRVFEEEH 701
           4577777777777777777777777777777777777777.556666666667777777777777777777777777777777777777 PP
   S: 180  tdsvyslsfdsng...kelvsgsldgtv..klwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlh 263
           +++v++ +f+ +      l+++s+d+ +  klw+l + +  +t  gh ++v+   fsp d++l + s Dg+++++ + s + +kt++ +
   Q: 702  EEQVNHCQFTNSTtprLLLATCSNDKVLntKLWNLNKPSSQNTIFGHFEPVNHCCFSPSDTYLSTSSNDGTVKLFHTSSANEWKTINVR 790
           77777777777666656677777777764457777777777777777777777777777777777777777777777777777777776 PP
   S: 264  n.....ssvisvav..lsf 275
                 +  + v++  +  
   Q: 791  DafaesDEEVLVKCstWTA 809
           6666664444444422333 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

LEEGARSCLM RFRHRLEDDI KPPYLMDHMV TDGVLTGDEE ERIKNQPSRK DQAAALLALL 60
LMKDNRAYIS FYNAMVQEGY NDLANLLHRD LPLGLPEGLK RSTDCCTPYV QTVLSEGGVP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGGAGGAAG GGGCGCGGAG CTGTCTGATG CGCTTTCGCC ACCGGCTGGA GGACGACATC 60
AAGCCCCCCT ACCTGATGGA CCACATGGTC ACTGACGGCG TGCTGACTGG CGACGAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR017251--Apaf-1
IPR001315--CARD
IPR011029--DEATH-like_dom
IPR002182--NB-ARC
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50209--CARD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00619--CARD
PF00931--NB-ARC
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0043293--C:apoptosome
GO:0043531--F:ADP binding
GO:0097190--P:apoptotic signaling pathway
GO:0042981--P:regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001432	Ailuropoda melanoleuca	52.08	0.00e+00	1312.00
IUUC-Apl-004201	Anas platyrhynchos	52.02	0.00e+00	1286.00
IUUC-Aca-004638	Anolis carolinensis	51.74	0.00e+00	1318.00
IUUC-Ame-011062	Astyanax mexicanus	66.69	0.00e+00	1666.00
IUUC-Bta-012865	Bos taurus	52.33	0.00e+00	1317.00
IUUC-Cja-018815	Callithrix jacchus	55.73	0.00e+00	1009.00
IUUC-Cfa-020222	Canis familiaris	49.34	0.00e+00	1212.00
IUUC-Cpo-021524	Cavia porcellus	52.52	0.00e+00	1320.00
IUUC-Csa-023861	Chlorocebus sabaeus	51.92	0.00e+00	1303.00
IUUC-Cho-024484	Choloepus hoffmanni	41.37	5.00e-168	585.00
IUUC-Dre-028006	Danio rerio	63.26	0.00e+00	1522.00
IUUC-Dno-029591	Dasypus novemcinctus	52.51	0.00e+00	1328.00
IUUC-Dor-030237	Dipodomys ordii	38.74	5.00e-136	479.00
IUUC-Ete-032620	Echinops telfairi	51.84	0.00e+00	639.00
IUUC-Eca-033569	Equus caballus	52.32	0.00e+00	1315.00
IUUC-Eeu-035354	Erinaceus europaeus	52.81	3.00e-90	327.00
IUUC-Fca-036337	Felis catus	51.61	0.00e+00	1307.00
IUUC-Fal-037077	Ficedula albicollis	52.03	0.00e+00	1269.00
IUUC-Gmo-039687	Gadus morhua	66.06	0.00e+00	1259.00
IUUC-Gga-040299	Gallus gallus	51.34	0.00e+00	1289.00
IUUC-Ggo-045563	Gorilla gorilla	52.08	0.00e+00	1309.00
IUUC-Hsa-046771	Homo sapiens	52.08	0.00e+00	1309.00
IUUC-Lch-050200	Latimeria chalumnae	54.06	0.00e+00	1315.00
IUUC-Loc-052090	Lepisosteus oculatus	61.67	0.00e+00	1538.00
IUUC-Laf-053861	Loxodonta africana	52.39	0.00e+00	1306.00
IUUC-Mcc-055543	Macaca mulatta	52.47	0.00e+00	1313.00
IUUC-Meu-056688	Macropus eugenii	53.24	0.00e+00	1293.00
IUUC-Mga-059243	Meleagris gallopavo	51.74	0.00e+00	1296.00
IUUC-Mmr-061134	Microcebus murinus	49.83	0.00e+00	1107.00
IUUC-Mdo-062913	Monodelphis domestica	53.07	0.00e+00	1288.00
IUUC-Mmu-063811	Mus musculus	52.40	0.00e+00	1310.00
IUUC-Mpu-066780	Mustela putorius furo	51.73	0.00e+00	1305.00
IUUC-Mlu-067276	Myotis lucifugus	52.31	0.00e+00	1319.00
IUUC-Nle-069129	Nomascus leucogenys	52.00	0.00e+00	1308.00
IUUC-Opr-071007	Ochotona princeps	45.45	1.00e-157	551.00
IUUC-Ont-071348	Oreochromis niloticus	77.48	0.00e+00	1976.00
IUUC-Oan-072717	Ornithorhynchus anatinus	52.96	0.00e+00	1343.00
IUUC-Ocu-074286	Oryctolagus cuniculus	51.44	0.00e+00	1091.00
IUUC-Ola-086895	Oryzias latipes	65.44	0.00e+00	1598.00
IUUC-Oga-088678	Otolemur garnettii	52.96	0.00e+00	1321.00
IUUC-Oar-089359	Ovis aries	52.72	0.00e+00	1320.00
IUUC-Ptr-091062	Pan troglodytes	52.15	0.00e+00	1310.00
IUUC-Pan-092528	Papio anubis	59.13	0.00e+00	888.00
IUUC-Psi-093430	Pelodiscus sinensis	53.40	0.00e+00	1312.00
IUUC-Pma-094690	Petromyzon marinus	38.24	2.00e-105	376.00
IUUC-Pfo-097204	Poecilia formosa	72.61	0.00e+00	1840.00
IUUC-Pab-097690	Pongo abelii	52.15	0.00e+00	1310.00
IUUC-Pca-100778	Procavia capensis	43.72	1.00e-152	534.00
IUUC-Pva-102870	Pteropus vampyrus	49.87	0.00e+00	1155.00
IUUC-Rno-104889	Rattus norvegicus	52.25	0.00e+00	1312.00
IUUC-Sha-107465	Sarcophilus harrisii	52.92	0.00e+00	1304.00
IUUC-Sar-113268	Sorex araneus	51.27	4.00e-104	373.00
IUUC-Ssc-115654	Sus scrofa	51.88	0.00e+00	1309.00
IUUC-Tgu-117302	Taeniopygia guttata	51.90	0.00e+00	1282.00
IUUC-Tru-118363	Takifugu rubripes	77.78	0.00e+00	1967.00
IUUC-Tsy-119007	Tarsius syrichta	49.76	0.00e+00	1228.00
IUUC-Tni-120910	Tetraodon nigroviridis	76.41	0.00e+00	1889.00
IUUC-Tbe-127413	Tupaia belangeri	44.94	0.00e+00	630.00
IUUC-Ttr-129213	Tursiops truncatus	48.19	0.00e+00	1164.00
IUUC-Vpa-130146	Vicugna pacos	48.47	0.00e+00	877.00
IUUC-Xtr-132559	Xenopus tropicalis	48.77	0.00e+00	1212.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence