iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036919

Ensembl Protein ID

ENSFALP00000013146.1

UniProt Accession

U3KDP2; U3KDP2_FICAL

Genbank Protein ID

ENSFALP00000013146

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01010391

Gene Name

UBR2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000012597.1	ENSFALT00000013201.1	ENSFALP00000013146.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/N-recognin/N-domain	1.10e-39	134.1	164	239
E3 activity/RING/RING	1.30e-09	38.1	1079	1184
E3 activity/N-recognin/UBR-box	1.60e-31	108.3	35	105

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/N-recognin/N-domain

   S: 1    YylvLfNDEkHsyeqviyslqkAleleqkeakkfatiidkeGRravkaGdyavceeakkeilknseklaqipLkVev 77
           Yy++LfNDE+H+yeqviy+lqkA++++qkea++fat++d++GRr+v++Gd+++c++ak++i++n++++++ pLkV+v
   Q: 164  YYCMLFNDEVHTYEQVIYTLQKAVNCTQKEAIGFATTVDRDGRRSVRYGDFQYCDQAKSVIVRNTSRQTK-PLKVQV 239
           9*********************************************************************.****98 PP

E3 activity/RING/RING

   S: 1    CaiC......................................ledf......kdgplvlpCgHvfhadClqkw.............. 29
           C++C                                      ++++      ++g+++++CgH++ha+C+q++              
   Q: 1079 CILCqeeqevkvdsramvlaafiqrstvlsknrnkitpdpekYDPLfmhpdlSCGTHTGSCGHIMHAHCWQRYfdavqakeqrrqqr 1165
           888833333333333333333333333333333333333333222244444455899****************************** PP
   S: 30   ...pglknssskefrCPlC 45
              + +++++++ef+CPlC
   Q: 1166 lrvHTSYDVENGEFLCPLC 1184
           ******************* PP

E3 activity/N-recognin/UBR-box

   S: 1    slCgrvfkvgetiyeCrtCsvdetlvlCteCfakvvHkdHeyklkksggggfCdCGdteAwedgskCkkll 71
           +lCgrvfkvge +y+Cr+C+vd+t+vlC+eCf  ++H++H+y++++sggggfCdCGdteAw++g++C+k++
   Q: 35   HLCGRVFKVGEPTYSCRDCAVDPTCVLCMECFLGSIHREHRYRMTTSGGGGFCDCGDTEAWKEGPYCQKHE 105
           68******************************************************************996 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MLAQHVLLGP MEWYLCGEDP AFGFPKLEQA NKPSHLCGRV FKVGEPTYSC RDCAVDPTCV 60
LCMECFLGSI HREHRYRMTT SGGGGFCDCG DTEAWKEGPY CQKHELNTSE TAEEEDPLVH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTTTGCAAT GGCATTTTAG ATATTTCATT TAGGAATAAA ATAACCTAAA TGACTGTGTT 60
TGGTGTGTTT ATTAATGAAG AATTTGTGTT CTCTTTTCTT CCAATATAAA AGAAATGGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003769--ClpS_core
IPR014719--Ribosomal_L7/12_C/ClpS-like
IPR011991--WHTH_DNA-bd_dom
IPR013083--Znf_RING/FYVE/PHD
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF02617--ClpS
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0000785--C:chromatin
GO:0000151--C:ubiquitin ligase complex
GO:0070728--F:leucine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0071233--P:cellular response to leucine
GO:0006342--P:chromatin silencing
GO:0033522--P:histone H2A ubiquitination
GO:0007141--P:male meiosis I
GO:0032007--P:negative regulation of TOR signaling
GO:0007283--P:spermatogenesis
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

fab:101808017

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000949	Aegilops tauschii	28.01	3.00e-22	101.00
IUUC-Aml-001876	Ailuropoda melanoleuca	78.17	0.00e+00	2532.00
IUUC-Atr-002501	Amborella trichopoda	29.72	5.00e-28	120.00
IUUC-Apl-003828	Anas platyrhynchos	95.24	0.00e+00	3245.00
IUUC-Aca-005189	Anolis carolinensis	86.78	0.00e+00	3013.00
IUUC-Aly-005901	Arabidopsis lyrata	31.46	1.00e-25	113.00
IUUC-Ath-007148	Arabidopsis thaliana	30.05	1.00e-24	109.00
IUUC-Ago-007946	Ashbya gossypii	22.65	8.00e-31	130.00
IUUC-Afu-008929	Aspergillus fumigatus	23.36	7.00e-50	193.00
IUUC-Ang-009550	Aspergillus niger	23.26	3.00e-45	177.00
IUUC-Ame-011917	Astyanax mexicanus	74.83	0.00e+00	2462.00
IUUC-Bta-012768	Bos taurus	85.59	0.00e+00	2921.00
IUUC-Bdi-014635	Brachypodium distachyon	26.14	4.00e-30	127.00
IUUC-Bol-015669	Brassica oleracea	30.39	6.00e-30	127.00
IUUC-Bra-017776	Brassica rapa	30.04	2.00e-29	125.00
IUUC-Cel-018476	Caenorhabditis elegans	28.99	2.00e-76	281.00
IUUC-Cja-019797	Callithrix jacchus	85.87	0.00e+00	2388.00
IUUC-Cfa-020950	Canis familiaris	87.78	0.00e+00	2982.00
IUUC-Cpo-022385	Cavia porcellus	85.81	0.00e+00	2939.00
IUUC-Csa-024082	Chlorocebus sabaeus	87.49	0.00e+00	2981.00
IUUC-Cho-025029	Choloepus hoffmanni	79.49	0.00e+00	1915.00
IUUC-Cin-025148	Ciona intestinalis	34.79	3.00e-134	472.00
IUUC-Csv-026296	Ciona savignyi	31.95	5.00e-22	98.60
IUUC-Cgl-026605	Colletotrichum gloeosporioides	23.61	1.00e-55	212.00
IUUC-Dre-028343	Danio rerio	73.55	0.00e+00	2473.00
IUUC-Dno-030002	Dasypus novemcinctus	85.57	0.00e+00	1815.00
IUUC-Dor-030207	Dipodomys ordii	87.93	0.00e+00	1153.00
IUUC-Dse-031531	Dothistroma septosporum	24.48	1.00e-51	199.00
IUUC-Dme-031910	Drosophila melanogaster	33.49	0.00e+00	677.00
IUUC-Ete-033162	Echinops telfairi	89.25	0.00e+00	1038.00
IUUC-Eca-033454	Equus caballus	86.92	0.00e+00	2960.00
IUUC-Eeu-034783	Erinaceus europaeus	74.27	0.00e+00	1338.00
IUUC-Fca-036588	Felis catus	87.28	0.00e+00	2964.00
IUUC-Fso-038463	Fusarium solani	23.76	2.00e-42	168.00
IUUC-Gmo-039698	Gadus morhua	70.36	0.00e+00	1587.00
IUUC-Gga-041123	Gallus gallus	95.47	0.00e+00	3276.00
IUUC-Gac-042622	Gasterosteus aculeatus	67.91	0.00e+00	2192.00
IUUC-Ggo-045583	Gorilla gorilla	85.95	0.00e+00	2951.00
IUUC-Hsa-046343	Homo sapiens	87.43	0.00e+00	2976.00
IUUC-Hvu-047626	Hordeum vulgare	28.98	5.00e-27	116.00
IUUC-Kpa-049088	Komagataella pastoris	22.49	8.00e-48	186.00
IUUC-Lch-049649	Latimeria chalumnae	76.01	0.00e+00	2542.00
IUUC-Loc-052818	Lepisosteus oculatus	78.79	0.00e+00	2679.00
IUUC-Laf-054142	Loxodonta africana	86.65	0.00e+00	2957.00
IUUC-Mcc-055677	Macaca mulatta	87.32	0.00e+00	2971.00
IUUC-Meu-056204	Macropus eugenii	67.77	0.00e+00	726.00
IUUC-Mpo-057372	Magnaporthe poae	25.50	6.00e-45	176.00
IUUC-Mtr-058538	Medicago truncatula	29.04	1.00e-27	119.00
IUUC-Mla-058963	Melampsora laricipopulina	23.47	5.00e-58	220.00
IUUC-Mga-059698	Meleagris gallopavo	95.19	0.00e+00	3261.00
IUUC-Mvi-060535	Microbotryum violaceum	24.37	3.00e-46	181.00
IUUC-Mmr-060901	Microcebus murinus	84.89	0.00e+00	2886.00
IUUC-Mdo-062014	Monodelphis domestica	89.40	0.00e+00	3064.00
IUUC-Mmu-063699	Mus musculus	84.13	0.00e+00	2861.00
IUUC-Mac-064773	Musa acuminata	30.74	7.00e-27	117.00
IUUC-Mpu-066153	Mustela putorius furo	87.67	0.00e+00	2983.00
IUUC-Mlu-068151	Myotis lucifugus	85.88	0.00e+00	2911.00
IUUC-Nfi-068403	Neosartorya fischeri	23.11	1.00e-49	192.00
IUUC-Ncr-068864	Neurospora crassa	22.67	1.00e-39	159.00
IUUC-Nle-069529	Nomascus leucogenys	87.55	0.00e+00	2985.00
IUUC-Opr-071107	Ochotona princeps	80.31	0.00e+00	1228.00
IUUC-Ont-072189	Oreochromis niloticus	67.83	0.00e+00	2168.00
IUUC-Oan-072893	Ornithorhynchus anatinus	88.01	0.00e+00	3003.00
IUUC-Ocu-074082	Oryctolagus cuniculus	85.57	0.00e+00	2913.00
IUUC-Olo-081056	Oryza longistaminata	24.18	1.00e-15	79.70
IUUC-Ome-081738	Oryza meridionalis	21.87	2.00e-14	75.50
IUUC-Ola-087460	Oryzias latipes	65.87	0.00e+00	2157.00
IUUC-Olu-087832	Ostreococcus lucimarinus	28.33	1.80e-02	34.70
IUUC-Oga-088432	Otolemur garnettii	87.04	0.00e+00	2980.00
IUUC-Oar-090206	Ovis aries	85.02	0.00e+00	2919.00
IUUC-Ptr-091180	Pan troglodytes	86.33	0.00e+00	2950.00
IUUC-Pan-092375	Papio anubis	87.38	0.00e+00	2981.00
IUUC-Psi-093049	Pelodiscus sinensis	90.39	0.00e+00	3065.00
IUUC-Ppa-095715	Physcomitrella patens	32.49	3.00e-23	105.00
IUUC-Pfo-096524	Poecilia formosa	65.45	0.00e+00	2054.00
IUUC-Pab-097989	Pongo abelii	85.87	0.00e+00	2903.00
IUUC-Pca-100207	Procavia capensis	74.31	0.00e+00	1162.00
IUUC-Ppe-101802	Prunus persica	28.52	1.00e-26	115.00
IUUC-Pva-102538	Pteropus vampyrus	84.35	0.00e+00	1098.00
IUUC-Pgr-103372	Puccinia graminis	23.04	6.00e-55	210.00
IUUC-Ptt-103878	Puccinia triticina	23.74	2.00e-43	171.00
IUUC-Rno-105567	Rattus norvegicus	82.92	0.00e+00	2799.00
IUUC-Sce-106272	Saccharomyces cerevisiae	21.32	1.00e-25	112.00
IUUC-Sha-106980	Sarcophilus harrisii	89.38	0.00e+00	3058.00
IUUC-Sja-107980	Schizosaccharomyces japonicus	23.48	5.00e-45	177.00
IUUC-Spo-108183	Schizosaccharomyces pombe	24.21	5.00e-49	190.00
IUUC-Smo-108719	Selaginella moellendorffii	32.26	3.00e-29	124.00
IUUC-Sit-110716	Setaria italica	25.27	5.00e-30	127.00
IUUC-Sly-111286	Solanum lycopersicum	28.01	8.00e-27	117.00
IUUC-Sar-113332	Sorex araneus	79.30	0.00e+00	2023.00
IUUC-Sbi-114577	Sorghum bicolor	27.89	6.00e-30	127.00
IUUC-Ssc-115525	Sus scrofa	86.84	0.00e+00	2269.00
IUUC-Tgu-116943	Taeniopygia guttata	97.05	0.00e+00	3318.00
IUUC-Tru-117673	Takifugu rubripes	66.94	0.00e+00	2174.00
IUUC-Tsy-119032	Tarsius syrichta	85.84	0.00e+00	1665.00
IUUC-Tni-119987	Tetraodon nigroviridis	66.32	0.00e+00	2120.00
IUUC-Tca-121077	Theobroma cacao	32.70	2.00e-26	115.00
IUUC-Tur-126562	Triticum urartu	28.46	6.00e-27	116.00
IUUC-Tbe-128103	Tupaia belangeri	80.95	0.00e+00	1144.00
IUUC-Ttr-128253	Tursiops truncatus	87.65	0.00e+00	1927.00
IUUC-Vpa-130540	Vicugna pacos	82.65	0.00e+00	2664.00
IUUC-Vvi-131290	Vitis vinifera	31.13	2.00e-26	115.00
IUUC-Xtr-132690	Xenopus tropicalis	80.70	0.00e+00	2790.00
IUUC-Xma-133748	Xiphophorus maculatus	64.27	0.00e+00	2020.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence