iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036000

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02139388

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000022680.1	ENSFCAT00000030663.1	ENSFCAP00000023021.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.70e-06	26.0	193	234

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle +   ++++v pC H fh++C+  w        ++ +CP Cr
   Q: 193  CAICLEKYidGEELRVIPCTHRFHRKCVDPW------LLQHHTCPHCR 234
           ********66334******************......9999******8 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MHPLGLCNNN DEEDLYEYGW VGVVKLEQPE LDPKPCLTVL GKAKRAVQRG ATAVIFDVSE 60
NPEAIDQLNQ GSEDPLKRPV VYVKGADAIK LMNIVNKQKV ARARIQHRPP RQPTEYFDMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNC GCGGCGCGGG CCAAGGAGAC GGCGTTTGTG GAGGTGGTGC 60
TGTTCGAGTC GAGCCCGAGC GGCGACTACA CCACCTACAC CACCGGCCTC ACGGGCCGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

KEGG

fca:101086348

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	90.85	0.00e+00	1306.00
IUUC-Apl-004188	Anas platyrhynchos	71.62	0.00e+00	1026.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	4.00e-15	73.60
IUUC-Ath-007372	Arabidopsis thaliana	42.17	7.00e-15	73.20
IUUC-Ame-011764	Astyanax mexicanus	62.05	0.00e+00	726.00
IUUC-Bta-012478	Bos taurus	67.77	0.00e+00	659.00
IUUC-Bol-016217	Brassica oleracea	52.73	3.00e-14	70.90
IUUC-Bra-017407	Brassica rapa	52.73	3.00e-14	70.90
IUUC-Cja-019504	Callithrix jacchus	86.58	0.00e+00	1309.00
IUUC-Cfa-020048	Canis familiaris	92.15	0.00e+00	1405.00
IUUC-Cpo-021725	Cavia porcellus	81.57	0.00e+00	1190.00
IUUC-Csa-023586	Chlorocebus sabaeus	86.73	0.00e+00	1276.00
IUUC-Cho-024867	Choloepus hoffmanni	91.54	0.00e+00	681.00
IUUC-Cin-025569	Ciona intestinalis	47.11	2.00e-55	210.00
IUUC-Csv-025869	Ciona savignyi	45.04	7.00e-49	188.00
IUUC-Dre-027553	Danio rerio	64.50	0.00e+00	801.00
IUUC-Dno-029370	Dasypus novemcinctus	85.54	0.00e+00	1204.00
IUUC-Dor-030816	Dipodomys ordii	78.33	0.00e+00	1088.00
IUUC-Ete-033060	Echinops telfairi	74.84	0.00e+00	835.00
IUUC-Eca-034044	Equus caballus	91.92	0.00e+00	1372.00
IUUC-Eeu-034591	Erinaceus europaeus	69.96	4.00e-146	511.00
IUUC-Fal-037147	Ficedula albicollis	70.30	0.00e+00	1031.00
IUUC-Gmo-039099	Gadus morhua	60.20	9.00e-112	397.00
IUUC-Gga-041243	Gallus gallus	68.04	0.00e+00	818.00
IUUC-Gac-041340	Gasterosteus aculeatus	50.00	3.00e-113	401.00
IUUC-Gma-044387	Glycine max	48.28	2.00e-14	72.40
IUUC-Ggo-044953	Gorilla gorilla	89.37	0.00e+00	1300.00
IUUC-Hsa-046484	Homo sapiens	88.28	0.00e+00	1306.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	86.14	0.00e+00	1273.00
IUUC-Lch-050004	Latimeria chalumnae	59.21	0.00e+00	667.00
IUUC-Loc-051830	Lepisosteus oculatus	65.92	0.00e+00	772.00
IUUC-Laf-053975	Loxodonta africana	84.84	0.00e+00	1235.00
IUUC-Mcc-055302	Macaca mulatta	87.09	0.00e+00	1254.00
IUUC-Meu-056263	Macropus eugenii	76.35	0.00e+00	792.00
IUUC-Mtr-058744	Medicago truncatula	54.17	2.00e-13	68.20
IUUC-Mga-059706	Meleagris gallopavo	71.94	0.00e+00	1053.00
IUUC-Mmr-061372	Microcebus murinus	86.22	0.00e+00	1201.00
IUUC-Mdo-062651	Monodelphis domestica	65.64	0.00e+00	872.00
IUUC-Mmu-064339	Mus musculus	82.26	0.00e+00	1207.00
IUUC-Mac-065356	Musa acuminata	50.00	1.00e-12	67.40
IUUC-Mpu-066211	Mustela putorius furo	89.13	0.00e+00	1333.00
IUUC-Mlu-067058	Myotis lucifugus	91.27	0.00e+00	1300.00
IUUC-Nle-069886	Nomascus leucogenys	87.97	0.00e+00	1288.00
IUUC-Opr-070218	Ochotona princeps	82.56	0.00e+00	1084.00
IUUC-Ont-072483	Oreochromis niloticus	60.77	0.00e+00	761.00
IUUC-Oan-073718	Ornithorhynchus anatinus	72.43	0.00e+00	907.00
IUUC-Ocu-073847	Oryctolagus cuniculus	81.25	0.00e+00	1049.00
IUUC-Oba-075528	Oryza barthii	43.64	3.00e-12	65.90
IUUC-Obr-076184	Oryza brachyantha	53.33	3.00e-12	66.20
IUUC-Ogl-076953	Oryza glaberrima	43.64	3.00e-12	66.20
IUUC-Oin-079189	Oryza indica	43.64	3.00e-12	65.90
IUUC-Oni-082648	Oryza nivara	43.64	3.00e-12	65.90
IUUC-Opu-083306	Oryza punctata	67.44	8.00e-13	66.60
IUUC-Ola-087358	Oryzias latipes	62.10	0.00e+00	772.00
IUUC-Oga-088362	Otolemur garnettii	85.44	0.00e+00	1291.00
IUUC-Oar-090197	Ovis aries	99.49	2.00e-96	346.00
IUUC-Ptr-091350	Pan troglodytes	88.16	0.00e+00	1305.00
IUUC-Pan-091700	Papio anubis	87.20	0.00e+00	1250.00
IUUC-Psi-093301	Pelodiscus sinensis	69.40	0.00e+00	987.00
IUUC-Pfo-096917	Poecilia formosa	62.22	0.00e+00	747.00
IUUC-Pab-097932	Pongo abelii	87.17	0.00e+00	1312.00
IUUC-Pop-099640	Populus trichocarpa	57.14	2.00e-14	72.40
IUUC-Pca-101054	Procavia capensis	93.60	0.00e+00	963.00
IUUC-Pva-102879	Pteropus vampyrus	91.92	0.00e+00	1375.00
IUUC-Pgr-103476	Puccinia graminis	41.27	4.00e-09	55.10
IUUC-Sha-106507	Sarcophilus harrisii	53.41	5.00e-163	568.00
IUUC-Sit-110656	Setaria italica	67.44	7.00e-13	66.60
IUUC-Stu-112500	Solanum tuberosum	62.79	1.00e-12	66.20
IUUC-Sar-113182	Sorex araneus	82.33	1.00e-111	397.00
IUUC-Sbi-114414	Sorghum bicolor	40.00	1.00e-12	65.50
IUUC-Ssc-115966	Sus scrofa	85.66	0.00e+00	1103.00
IUUC-Tgu-116864	Taeniopygia guttata	62.64	0.00e+00	671.00
IUUC-Tru-118502	Takifugu rubripes	60.10	0.00e+00	726.00
IUUC-Tsy-119210	Tarsius syrichta	85.75	0.00e+00	1254.00
IUUC-Tni-120344	Tetraodon nigroviridis	52.56	9.00e-121	427.00
IUUC-Tca-120966	Theobroma cacao	48.44	2.00e-13	70.10
IUUC-Tbe-127735	Tupaia belangeri	81.63	6.00e-133	468.00
IUUC-Ttr-128714	Tursiops truncatus	79.57	0.00e+00	1031.00
IUUC-Vvi-131280	Vitis vinifera	31.50	4.00e-13	68.90
IUUC-Xtr-132280	Xenopus tropicalis	59.97	0.00e+00	694.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence