iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067058

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02038450

Gene Name

ZNRF3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000011996.2	ENSMLUT00000012000.2	ENSMLUP00000010930.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.30e-06	26.1	153	194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle +   ++++v pC H fh++C+  w        ++ +CP Cr
   Q: 153  CAICLEKYidGEELRVIPCTHRFHRKCVDPW------LLQHHTCPHCR 194
           ********66334******************......9999******8 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

GKAKRAVQRG ATAVIFDVSE NPEAIDQLNQ GQEDPLKRPV VYVKGADAIK LMNIVNKQKV 60
ARARIQHRPP RQPTEYFDMG IFLAFFVVVS LVCLILLVKI KLKQRRSQNS MNRLAVQALE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAAGGTCA GAGGGCCAGA ATGCCAACCT GCTCTGTTTC CTTCTGCCAG GCCAAGCGAG 60
CGGTGCAGCG GGGAGCCACC GCCGTCATCT TCGATGTGTC TGAAAACCCA GAAGCTATCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060070--P:canonical Wnt signaling pathway
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:0072089--P:stem cell proliferation
GO:0006511--P:ubiquitin-dependent protein catabolic process
GO:0038018--P:Wnt receptor catabolic process
GO:0060071--P:Wnt signaling pathway, planar cell polarity pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001916	Ailuropoda melanoleuca	88.78	0.00e+00	1162.00
IUUC-Apl-004188	Anas platyrhynchos	71.19	0.00e+00	943.00
IUUC-Aly-005850	Arabidopsis lyrata	42.68	1.00e-14	72.40
IUUC-Ath-007372	Arabidopsis thaliana	42.68	1.00e-14	72.00
IUUC-Ame-011764	Astyanax mexicanus	63.19	0.00e+00	724.00
IUUC-Bta-012478	Bos taurus	68.69	0.00e+00	671.00
IUUC-Bci-013936	Botrytis cinerea	52.17	3.00e-12	66.60
IUUC-Bdi-014078	Brachypodium distachyon	62.79	2.00e-12	65.90
IUUC-Bol-016217	Brassica oleracea	56.25	3.00e-14	70.90
IUUC-Bra-017407	Brassica rapa	56.25	3.00e-14	70.90
IUUC-Cja-019504	Callithrix jacchus	88.07	0.00e+00	1228.00
IUUC-Cfa-020048	Canis familiaris	90.33	0.00e+00	1264.00
IUUC-Cpo-021725	Cavia porcellus	81.61	0.00e+00	1107.00
IUUC-Csa-023586	Chlorocebus sabaeus	88.42	0.00e+00	1187.00
IUUC-Cho-024867	Choloepus hoffmanni	91.69	0.00e+00	686.00
IUUC-Cin-025569	Ciona intestinalis	45.05	3.00e-40	160.00
IUUC-Dre-027553	Danio rerio	62.71	0.00e+00	718.00
IUUC-Dno-029370	Dasypus novemcinctus	84.15	0.00e+00	1121.00
IUUC-Dor-030816	Dipodomys ordii	79.00	0.00e+00	996.00
IUUC-Ete-033060	Echinops telfairi	74.18	0.00e+00	823.00
IUUC-Eca-034044	Equus caballus	91.71	0.00e+00	1259.00
IUUC-Eeu-034591	Erinaceus europaeus	68.43	3.00e-144	505.00
IUUC-Fca-036000	Felis catus	92.39	0.00e+00	1291.00
IUUC-Fal-037147	Ficedula albicollis	70.18	0.00e+00	949.00
IUUC-Fox-038011	Fusarium oxysporum	49.09	3.00e-12	67.00
IUUC-Gmo-039099	Gadus morhua	51.48	6.00e-120	424.00
IUUC-Gga-041243	Gallus gallus	68.36	0.00e+00	810.00
IUUC-Gac-041340	Gasterosteus aculeatus	50.34	5.00e-115	408.00
IUUC-Gma-044387	Glycine max	50.00	5.00e-15	74.30
IUUC-Ggo-044953	Gorilla gorilla	89.22	0.00e+00	1213.00
IUUC-Hsa-046484	Homo sapiens	89.32	0.00e+00	1224.00
IUUC-Itr-048470	Ictidomys tridecemlineatus	85.50	0.00e+00	1174.00
IUUC-Lch-050004	Latimeria chalumnae	58.79	0.00e+00	667.00
IUUC-Loc-051830	Lepisosteus oculatus	63.36	0.00e+00	701.00
IUUC-Laf-053975	Loxodonta africana	86.39	0.00e+00	1168.00
IUUC-Mcc-055302	Macaca mulatta	88.17	0.00e+00	1154.00
IUUC-Meu-056263	Macropus eugenii	77.41	0.00e+00	704.00
IUUC-Mtr-058744	Medicago truncatula	54.17	2.00e-13	68.60
IUUC-Mga-059706	Meleagris gallopavo	71.16	0.00e+00	956.00
IUUC-Mmr-061372	Microcebus murinus	87.31	0.00e+00	1115.00
IUUC-Mdo-062651	Monodelphis domestica	63.80	0.00e+00	772.00
IUUC-Mmu-064339	Mus musculus	83.51	0.00e+00	1130.00
IUUC-Mpu-066211	Mustela putorius furo	88.03	0.00e+00	1215.00
IUUC-Nle-069886	Nomascus leucogenys	89.17	0.00e+00	1201.00
IUUC-Opr-070218	Ochotona princeps	82.78	0.00e+00	1078.00
IUUC-Ont-072483	Oreochromis niloticus	59.59	0.00e+00	689.00
IUUC-Oan-073718	Ornithorhynchus anatinus	70.52	0.00e+00	811.00
IUUC-Ocu-073847	Oryctolagus cuniculus	77.53	0.00e+00	940.00
IUUC-Oba-075528	Oryza barthii	43.64	3.00e-12	66.20
IUUC-Ogl-076953	Oryza glaberrima	43.64	3.00e-12	66.20
IUUC-Opu-083306	Oryza punctata	67.44	6.00e-13	67.40
IUUC-Oru-084953	Oryza rufipogon	53.06	2.00e-11	63.20
IUUC-Osa-085734	Oryza sativa	53.06	2.00e-11	63.20
IUUC-Ola-087358	Oryzias latipes	61.85	0.00e+00	696.00
IUUC-Oga-088362	Otolemur garnettii	85.99	0.00e+00	1199.00
IUUC-Oar-090197	Ovis aries	98.48	6.00e-96	345.00
IUUC-Ptr-091350	Pan troglodytes	89.07	0.00e+00	1222.00
IUUC-Pan-091700	Papio anubis	88.17	0.00e+00	1150.00
IUUC-Psi-093301	Pelodiscus sinensis	69.08	0.00e+00	901.00
IUUC-Pfo-096917	Poecilia formosa	62.19	0.00e+00	679.00
IUUC-Pab-097932	Pongo abelii	88.82	0.00e+00	1235.00
IUUC-Pop-099640	Populus trichocarpa	57.14	1.00e-14	72.80
IUUC-Pca-101054	Procavia capensis	92.71	0.00e+00	872.00
IUUC-Ppe-101991	Prunus persica	54.17	3.00e-13	67.80
IUUC-Pva-102879	Pteropus vampyrus	91.33	0.00e+00	1298.00
IUUC-Pgr-103476	Puccinia graminis	41.27	3.00e-09	55.80
IUUC-Sha-106507	Sarcophilus harrisii	53.88	1.00e-156	546.00
IUUC-Ssl-108601	Sclerotinia sclerotiorum	52.17	4.00e-12	65.90
IUUC-Sit-110656	Setaria italica	67.44	5.00e-13	67.40
IUUC-Sar-113182	Sorex araneus	86.31	3.00e-97	349.00
IUUC-Ssc-115966	Sus scrofa	85.77	0.00e+00	1087.00
IUUC-Tgu-116864	Taeniopygia guttata	64.26	0.00e+00	676.00
IUUC-Tru-118502	Takifugu rubripes	59.75	0.00e+00	656.00
IUUC-Tsy-119210	Tarsius syrichta	86.31	0.00e+00	1162.00
IUUC-Tni-120344	Tetraodon nigroviridis	53.18	4.00e-124	438.00
IUUC-Tca-120966	Theobroma cacao	48.44	1.00e-13	70.50
IUUC-Tbe-127735	Tupaia belangeri	86.24	4.00e-135	475.00
IUUC-Ttr-128714	Tursiops truncatus	77.36	0.00e+00	932.00
IUUC-Vda-129899	Verticillium dahliae	50.00	3.00e-11	63.50
IUUC-Vvi-131280	Vitis vinifera	31.50	3.00e-13	69.30
IUUC-Xtr-132280	Xenopus tropicalis	56.54	3.00e-171	595.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence