iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028400

UUCD1 version

UUC-DaR-00256

Ensembl Protein ID

ENSDARP00000123393.3

UniProt Accession

E7EYP4; F1QHP5; E7EYP4_DANRE

Genbank Protein ID

ENSDARP00000123393

Protein Name

Si:ch1073-440b2.1

Genbank Nucleotide ID

CU459183

Gene Name

si:ch1073-440b2.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000089138.4	ENSDART00000148175.3	ENSDARP00000123393.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.00e-08	35.1	192	239
E3 activity/RING/RING	5.60e-06	27.7	195	233

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqpltee 53
           +f C++ + l+ +Pv++p+G+t+  +++e++l+++ + cP++++ l+e 
   Q: 192  DFECSLCMRLFYEPVTTPCGHTFCLKCLERCLDHNPN-CPLCKENLSEY 239
           79**********************************9.********875 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+  f + p+++pCgH+f+++Cl++          + +CPlC+
   Q: 195  CSLCMRLFYE-PVTTPCGHTFCLKCLERC------LDHNPNCPLCK 233
           ****999977.***************999......99********7 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MEMKNFSQAI KDGDTMCQLR PLWPRAHYIK ATALRSAGSS EEALQEYLFC AALKPDWIAV 60
KLEAQKILSH MFSSVFVNDG LATSLPACTS RIKPTSLLSS LNTIIPRDGT KAGCSKDLTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTTAGCTAC ATTTTTTTAG CTTAAACCTT AAAATGACTT AAAGTTCTGT TACATTTGAT 60
TTCTGATAGT AACACATCTT TATTTCTTCA CAGAGCCCTC TATAGGTAGG CTCCTGGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR007110--Ig-like_dom
IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR011990--TPR-like_helical_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50835--IG_LIKE
PS51787--LON_N
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg

SMART

SM00464--LON
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

KEGG

dre:100000190

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001867	Ailuropoda melanoleuca	51.84	3.00e-139	488.00
IUUC-Apl-003355	Anas platyrhynchos	61.17	0.00e+00	633.00
IUUC-Aca-004822	Anolis carolinensis	60.04	3.00e-179	622.00
IUUC-Ang-009643	Aspergillus niger	28.57	3.00e-38	153.00
IUUC-Ame-010750	Astyanax mexicanus	72.16	0.00e+00	709.00
IUUC-Bta-012872	Bos taurus	51.52	2.00e-133	469.00
IUUC-Cja-019041	Callithrix jacchus	51.12	1.00e-138	487.00
IUUC-Cfa-020025	Canis familiaris	51.13	9.00e-140	491.00
IUUC-Cpo-022041	Cavia porcellus	50.82	5.00e-131	461.00
IUUC-Csa-023324	Chlorocebus sabaeus	50.41	2.00e-137	482.00
IUUC-Csv-026364	Ciona savignyi	44.22	1.00e-77	283.00
IUUC-Cgl-026514	Colletotrichum gloeosporioides	34.69	4.00e-44	172.00
IUUC-Cne-026875	Cryptococcus neoformans	26.19	4.00e-07	50.10
IUUC-Cme-027153	Cyanidioschyzon merolae	29.79	1.00e-27	117.00
IUUC-Dor-031132	Dipodomys ordii	50.31	1.00e-133	470.00
IUUC-Dme-031919	Drosophila melanogaster	37.35	8.00e-64	239.00
IUUC-Eca-033382	Equus caballus	50.72	2.00e-132	466.00
IUUC-Fca-036276	Felis catus	51.22	4.00e-140	491.00
IUUC-Fal-036669	Ficedula albicollis	61.55	0.00e+00	635.00
IUUC-Fso-038334	Fusarium solani	39.32	2.00e-41	164.00
IUUC-Gmo-039511	Gadus morhua	82.33	3.00e-144	505.00
IUUC-Gga-041253	Gallus gallus	61.75	0.00e+00	634.00
IUUC-Gac-041782	Gasterosteus aculeatus	80.37	1.00e-153	537.00
IUUC-Ggo-045501	Gorilla gorilla	50.61	4.00e-138	485.00
IUUC-Hsa-046630	Homo sapiens	51.02	2.00e-138	486.00
IUUC-Itr-048224	Ictidomys tridecemlineatus	51.13	4.00e-138	484.00
IUUC-Lch-049788	Latimeria chalumnae	62.26	0.00e+00	632.00
IUUC-Loc-051922	Lepisosteus oculatus	66.86	0.00e+00	685.00
IUUC-Lma-053145	Leptosphaeria maculans	28.36	8.00e-39	155.00
IUUC-Laf-053434	Loxodonta africana	50.83	9.00e-129	454.00
IUUC-Mcc-054828	Macaca mulatta	50.41	7.00e-137	480.00
IUUC-Meu-055901	Macropus eugenii	46.46	7.00e-121	427.00
IUUC-Mor-056963	Magnaporthe oryzae	37.50	3.00e-42	166.00
IUUC-Mla-058946	Melampsora laricipopulina	34.02	8.00e-43	168.00
IUUC-Mga-059760	Meleagris gallopavo	61.09	0.00e+00	632.00
IUUC-Mmr-060749	Microcebus murinus	51.12	3.00e-135	476.00
IUUC-Mdo-062203	Monodelphis domestica	58.91	7.00e-174	604.00
IUUC-Mmu-064118	Mus musculus	48.78	9.00e-135	473.00
IUUC-Mpu-065764	Mustela putorius furo	51.63	8.00e-143	501.00
IUUC-Mlu-067769	Myotis lucifugus	49.49	6.00e-130	458.00
IUUC-Nle-069616	Nomascus leucogenys	50.82	6.00e-138	484.00
IUUC-Ont-072142	Oreochromis niloticus	67.05	0.00e+00	682.00
IUUC-Oan-073179	Ornithorhynchus anatinus	68.13	3.00e-139	488.00
IUUC-Ocu-074884	Oryctolagus cuniculus	52.56	3.00e-130	459.00
IUUC-Ola-086534	Oryzias latipes	61.27	3.00e-174	605.00
IUUC-Oga-088972	Otolemur garnettii	51.53	6.00e-141	494.00
IUUC-Oar-089903	Ovis aries	51.52	5.00e-133	468.00
IUUC-Ptr-090992	Pan troglodytes	50.61	2.00e-138	486.00
IUUC-Pan-092180	Papio anubis	49.29	3.00e-131	462.00
IUUC-Psi-093423	Pelodiscus sinensis	62.48	0.00e+00	644.00
IUUC-Pma-094231	Petromyzon marinus	62.77	3.00e-113	401.00
IUUC-Pno-094889	Phaeosphaeria nodorum	37.13	3.00e-39	155.00
IUUC-Pfo-096363	Poecilia formosa	67.11	0.00e+00	660.00
IUUC-Pab-097974	Pongo abelii	50.41	6.00e-137	481.00
IUUC-Pca-100905	Procavia capensis	47.72	3.00e-91	329.00
IUUC-Pva-102242	Pteropus vampyrus	52.60	2.00e-124	439.00
IUUC-Ptt-103898	Puccinia triticina	27.11	6.00e-27	115.00
IUUC-Rno-105905	Rattus norvegicus	49.19	4.00e-137	481.00
IUUC-Sha-107565	Sarcophilus harrisii	64.03	6.00e-121	428.00
IUUC-Sre-114977	Sporisorium reilianum	32.16	1.00e-34	142.00
IUUC-Ssc-115705	Sus scrofa	50.21	3.00e-131	462.00
IUUC-Tgu-117000	Taeniopygia guttata	61.17	0.00e+00	631.00
IUUC-Tru-118016	Takifugu rubripes	65.95	0.00e+00	663.00
IUUC-Tsy-118988	Tarsius syrichta	50.51	6.00e-137	481.00
IUUC-Tni-119913	Tetraodon nigroviridis	66.13	3.00e-180	625.00
IUUC-Ttr-128875	Tursiops truncatus	67.76	2.00e-122	433.00
IUUC-Uma-129541	Ustilago maydis	32.17	3.00e-34	141.00
IUUC-Vda-129721	Verticillium dahliae	35.55	2.00e-35	143.00
IUUC-Vpa-130779	Vicugna pacos	67.13	2.00e-113	403.00
IUUC-Xtr-132065	Xenopus tropicalis	61.90	5.00e-179	621.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence