iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054278

Ensembl Protein ID

ENSLAFP00000013811.3

UniProt Accession

G3TH11; G3TH11_LOXAF

Protein Name

Uncharacterized protein

Gene Name

UBQLN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000016447.3	ENSLAFT00000016446.3	ENSLAFP00000013811.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	5.70e-10	39.4	547	584
ULD/UDP/UBQ/UBQ_PIM	5.80e-25	87.4	37	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 547  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 584
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 37   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 110
           99**********.***********************************************************987 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MAESGESGGP PDSQDGAAAP DAAGAPAAAA SAEPKIMKVT VKTPKEKEEF AVPENSSVQQ 60
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCCGAGA GTGGTGAAAG CGGCGGCCCT CCAGACTCCC AGGACGGCGC CGCCGCGCCC 60
GACGCTGCCG GCGCCCCCGC GGCAGCTGCC TCCGCGGAGC CCAAGATCAT GAAAGTCACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

lav:100662832

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	8.00e-38	151.00
IUUC-Aml-001461	Ailuropoda melanoleuca	94.16	0.00e+00	803.00
IUUC-Atr-002470	Amborella trichopoda	39.56	8.00e-44	171.00
IUUC-Apl-003241	Anas platyrhynchos	83.58	0.00e+00	719.00
IUUC-Aca-004511	Anolis carolinensis	80.82	0.00e+00	718.00
IUUC-Aly-005419	Arabidopsis lyrata	36.36	1.00e-50	193.00
IUUC-Ath-007271	Arabidopsis thaliana	38.66	1.00e-45	177.00
IUUC-Ago-007963	Ashbya gossypii	37.68	1.00e-08	54.30
IUUC-Bta-013048	Bos taurus	93.87	0.00e+00	821.00
IUUC-Bdi-014506	Brachypodium distachyon	35.62	4.00e-51	195.00
IUUC-Bol-015326	Brassica oleracea	35.20	3.00e-45	176.00
IUUC-Bra-018014	Brassica rapa	38.01	9.00e-42	164.00
IUUC-Cel-018631	Caenorhabditis elegans	38.26	1.00e-66	246.00
IUUC-Cja-019976	Callithrix jacchus	95.14	0.00e+00	831.00
IUUC-Cfa-020092	Canis familiaris	94.77	0.00e+00	829.00
IUUC-Cpo-022388	Cavia porcellus	92.61	0.00e+00	811.00
IUUC-Csa-024087	Chlorocebus sabaeus	95.26	0.00e+00	828.00
IUUC-Cho-024834	Choloepus hoffmanni	96.16	0.00e+00	842.00
IUUC-Cin-025136	Ciona intestinalis	51.10	8.00e-114	404.00
IUUC-Cme-027155	Cyanidioschyzon merolae	58.10	1.00e-34	140.00
IUUC-Dno-029647	Dasypus novemcinctus	77.35	1.00e-159	556.00
IUUC-Dor-030519	Dipodomys ordii	93.35	0.00e+00	795.00
IUUC-Dme-032013	Drosophila melanogaster	46.20	6.00e-112	397.00
IUUC-Ete-032273	Echinops telfairi	94.90	0.00e+00	810.00
IUUC-Eca-033667	Equus caballus	94.23	0.00e+00	832.00
IUUC-Eeu-034727	Erinaceus europaeus	77.20	6.00e-157	547.00
IUUC-Fca-036179	Felis catus	92.09	0.00e+00	785.00
IUUC-Fal-037642	Ficedula albicollis	82.77	0.00e+00	772.00
IUUC-Gga-041264	Gallus gallus	83.57	0.00e+00	808.00
IUUC-Gma-042681	Glycine max	36.18	1.00e-37	150.00
IUUC-Ggo-044969	Gorilla gorilla	95.68	0.00e+00	811.00
IUUC-Hsa-046669	Homo sapiens	95.50	0.00e+00	840.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	94.84	0.00e+00	674.00
IUUC-Lch-050192	Latimeria chalumnae	78.56	0.00e+00	680.00
IUUC-Lpe-051401	Leersia perrieri	36.28	5.00e-36	145.00
IUUC-Loc-052846	Lepisosteus oculatus	77.61	0.00e+00	674.00
IUUC-Lma-053152	Leptosphaeria maculans	30.86	5.00e-11	62.80
IUUC-Mcc-055680	Macaca mulatta	95.32	0.00e+00	840.00
IUUC-Meu-056414	Macropus eugenii	79.39	2.00e-156	545.00
IUUC-Mtr-058674	Medicago truncatula	36.86	3.00e-40	159.00
IUUC-Mga-059894	Meleagris gallopavo	82.64	0.00e+00	637.00
IUUC-Mmr-061094	Microcebus murinus	95.32	0.00e+00	818.00
IUUC-Mdo-062728	Monodelphis domestica	85.86	0.00e+00	772.00
IUUC-Mmu-064088	Mus musculus	86.15	0.00e+00	824.00
IUUC-Mac-065458	Musa acuminata	34.35	1.00e-43	171.00
IUUC-Mpu-066282	Mustela putorius furo	91.37	0.00e+00	799.00
IUUC-Mlu-068158	Myotis lucifugus	93.87	0.00e+00	792.00
IUUC-Nle-069321	Nomascus leucogenys	95.32	0.00e+00	840.00
IUUC-Opr-071098	Ochotona princeps	87.35	1.00e-178	619.00
IUUC-Oan-072808	Ornithorhynchus anatinus	86.64	0.00e+00	735.00
IUUC-Ocu-074301	Oryctolagus cuniculus	86.23	0.00e+00	782.00
IUUC-Oba-074973	Oryza barthii	39.67	6.00e-43	168.00
IUUC-Obr-076444	Oryza brachyantha	49.67	3.00e-32	133.00
IUUC-Ogl-077319	Oryza glaberrima	34.62	2.00e-44	173.00
IUUC-Ogu-078074	Oryza glumaepatula	34.62	2.00e-44	173.00
IUUC-Oin-079142	Oryza indica	33.49	7.00e-45	174.00
IUUC-Olo-080565	Oryza longistaminata	34.46	5.00e-44	172.00
IUUC-Ome-081155	Oryza meridionalis	50.92	6.00e-34	139.00
IUUC-Oni-082272	Oryza nivara	33.49	7.00e-45	174.00
IUUC-Opu-083241	Oryza punctata	35.36	1.00e-50	194.00
IUUC-Oru-085257	Oryza rufipogon	33.49	7.00e-45	174.00
IUUC-Osa-086257	Oryza sativa	34.62	2.00e-44	173.00
IUUC-Olu-087597	Ostreococcus lucimarinus	32.48	1.00e-25	111.00
IUUC-Oga-088495	Otolemur garnettii	94.41	0.00e+00	794.00
IUUC-Oar-089711	Ovis aries	93.55	0.00e+00	796.00
IUUC-Ptr-091439	Pan troglodytes	95.14	0.00e+00	832.00
IUUC-Pan-092641	Papio anubis	95.32	0.00e+00	840.00
IUUC-Psi-093518	Pelodiscus sinensis	84.08	0.00e+00	722.00
IUUC-Pma-094727	Petromyzon marinus	42.07	1.00e-51	197.00
IUUC-Ppa-095193	Physcomitrella patens	52.80	1.00e-35	144.00
IUUC-Pfo-096638	Poecilia formosa	67.32	2.00e-171	595.00
IUUC-Pab-098699	Pongo abelii	93.33	0.00e+00	831.00
IUUC-Pop-099549	Populus trichocarpa	36.05	2.00e-51	196.00
IUUC-Pca-100497	Procavia capensis	84.38	3.00e-134	472.00
IUUC-Ppe-101901	Prunus persica	35.07	4.00e-54	205.00
IUUC-Pva-102513	Pteropus vampyrus	82.16	8.00e-146	510.00
IUUC-Rno-104908	Rattus norvegicus	86.66	0.00e+00	855.00
IUUC-Sha-106881	Sarcophilus harrisii	83.58	0.00e+00	697.00
IUUC-Smo-108910	Selaginella moellendorffii	36.91	1.00e-38	154.00
IUUC-Sit-110766	Setaria italica	38.89	2.00e-36	146.00
IUUC-Sar-113648	Sorex araneus	88.52	0.00e+00	628.00
IUUC-Sbi-114307	Sorghum bicolor	39.46	9.00e-45	174.00
IUUC-Ssc-115820	Sus scrofa	95.50	0.00e+00	832.00
IUUC-Tgu-116845	Taeniopygia guttata	77.01	0.00e+00	681.00
IUUC-Tsy-119008	Tarsius syrichta	76.83	2.00e-152	532.00
IUUC-Tni-119780	Tetraodon nigroviridis	66.49	5.00e-170	590.00
IUUC-Tca-121558	Theobroma cacao	33.48	2.00e-53	203.00
IUUC-Tae-125419	Triticum aestivum	49.65	8.00e-38	151.00
IUUC-Tur-126248	Triticum urartu	48.95	1.00e-37	151.00
IUUC-Tbe-127379	Tupaia belangeri	82.45	0.00e+00	662.00
IUUC-Ttr-128630	Tursiops truncatus	91.72	0.00e+00	838.00
IUUC-Vpa-130413	Vicugna pacos	70.14	1.00e-158	552.00
IUUC-Vvi-131599	Vitis vinifera	40.55	2.00e-44	173.00
IUUC-Xtr-132595	Xenopus tropicalis	79.89	0.00e+00	700.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence