iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093825

Ensembl Protein ID

ENSPSIP00000019266.1

UniProt Accession

K7GG55; K7GG55_PELSI

Genbank Protein ID

ENSPSIP00000019266

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01032188

Gene Name

LATS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000017097.1	ENSPSIT00000019356.1	ENSPSIP00000019266.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.70e-07	31.2	103	140

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l+ l++ GFd++ +++aLr++ + ++eaA+e++ 
   Q: 103  NRQMLQDLQAAGFDEDMVVRALRQTnSRSIEAAIEFIS 140
           679*********************99*********975 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MKRSEKPEGY RQMRPKTFPA SNYTGSSRQM LQEIRESLRN LPKPSDAAKA EHNMGKMSAE 60
DPRQGRNPPK FVTYHKALQE IRNSLQPFAN ETSSSARGTS EINRQMLQDL QAAGFDEDMV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGAGAA GTGAGAAGCC AGAAGGATAT AGACAAATGA GGCCTAAGAC TTTTCCTGCT 60
AGTAACTACA CTGGCAGCAG CCGGCAAATG TTACAAGAAA TACGGGAGAG CCTTAGGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR028741--LATS1/Warts
IPR000719--Prot_kinase_dom
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase
PF00627--UBA

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0051220--P:cytoplasmic sequestering of protein
GO:0000086--P:G2/M transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0030216--P:keratinocyte differentiation
GO:0007067--P:mitotic nuclear division
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0030833--P:regulation of actin filament polymerization
GO:0033146--P:regulation of intracellular estrogen receptor signaling pathway
GO:2000058--P:regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0000819--P:sister chromatid segregation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001895	Ailuropoda melanoleuca	85.07	0.00e+00	1489.00
IUUC-Apl-003278	Anas platyrhynchos	88.16	0.00e+00	1583.00
IUUC-Aca-005319	Anolis carolinensis	85.27	0.00e+00	1511.00
IUUC-Bta-013438	Bos taurus	84.76	0.00e+00	1454.00
IUUC-Cja-019072	Callithrix jacchus	85.17	0.00e+00	1518.00
IUUC-Cfa-021267	Canis familiaris	85.17	0.00e+00	1502.00
IUUC-Cpo-021496	Cavia porcellus	82.00	0.00e+00	1477.00
IUUC-Csa-023255	Chlorocebus sabaeus	85.89	0.00e+00	1499.00
IUUC-Cho-024461	Choloepus hoffmanni	96.95	0.00e+00	757.00
IUUC-Dno-029888	Dasypus novemcinctus	82.90	0.00e+00	1477.00
IUUC-Dor-030144	Dipodomys ordii	74.15	0.00e+00	1212.00
IUUC-Ete-032813	Echinops telfairi	88.79	0.00e+00	856.00
IUUC-Eca-033781	Equus caballus	84.55	0.00e+00	1476.00
IUUC-Eeu-035007	Erinaceus europaeus	82.80	0.00e+00	1429.00
IUUC-Fca-036142	Felis catus	79.81	0.00e+00	1376.00
IUUC-Fal-036626	Ficedula albicollis	87.13	0.00e+00	1574.00
IUUC-Gga-040553	Gallus gallus	87.95	0.00e+00	1589.00
IUUC-Gac-042031	Gasterosteus aculeatus	63.65	0.00e+00	1043.00
IUUC-Ggo-045242	Gorilla gorilla	85.79	0.00e+00	1508.00
IUUC-Hsa-046081	Homo sapiens	85.48	0.00e+00	1499.00
IUUC-Itr-048668	Ictidomys tridecemlineatus	85.57	0.00e+00	1234.00
IUUC-Lch-049425	Latimeria chalumnae	80.08	0.00e+00	1389.00
IUUC-Loc-052418	Lepisosteus oculatus	67.72	0.00e+00	1121.00
IUUC-Laf-053710	Loxodonta africana	84.67	0.00e+00	1464.00
IUUC-Mcc-055079	Macaca mulatta	85.99	0.00e+00	1498.00
IUUC-Mga-059713	Meleagris gallopavo	88.26	0.00e+00	1600.00
IUUC-Mmr-061728	Microcebus murinus	85.48	0.00e+00	1483.00
IUUC-Mdo-061942	Monodelphis domestica	84.69	0.00e+00	1477.00
IUUC-Mmu-063504	Mus musculus	83.73	0.00e+00	1453.00
IUUC-Mpu-066034	Mustela putorius furo	84.35	0.00e+00	1475.00
IUUC-Mlu-067986	Myotis lucifugus	84.24	0.00e+00	1477.00
IUUC-Nle-069202	Nomascus leucogenys	85.58	0.00e+00	1505.00
IUUC-Opr-070801	Ochotona princeps	90.13	0.00e+00	880.00
IUUC-Ont-072487	Oreochromis niloticus	58.38	0.00e+00	956.00
IUUC-Oan-073128	Ornithorhynchus anatinus	84.75	0.00e+00	1286.00
IUUC-Ocu-073998	Oryctolagus cuniculus	86.71	0.00e+00	1000.00
IUUC-Ola-086858	Oryzias latipes	59.10	0.00e+00	942.00
IUUC-Oga-088874	Otolemur garnettii	84.14	0.00e+00	1458.00
IUUC-Oar-089236	Ovis aries	84.65	0.00e+00	1464.00
IUUC-Ptr-091425	Pan troglodytes	85.68	0.00e+00	1503.00
IUUC-Pan-091851	Papio anubis	86.20	0.00e+00	1503.00
IUUC-Pfo-096326	Poecilia formosa	57.68	0.00e+00	924.00
IUUC-Pab-097815	Pongo abelii	85.79	0.00e+00	1505.00
IUUC-Pva-102836	Pteropus vampyrus	83.01	0.00e+00	1387.00
IUUC-Rno-106053	Rattus norvegicus	83.63	0.00e+00	1467.00
IUUC-Sha-106843	Sarcophilus harrisii	85.48	0.00e+00	1511.00
IUUC-Sar-113649	Sorex araneus	84.09	0.00e+00	1048.00
IUUC-Ssc-115486	Sus scrofa	94.00	0.00e+00	813.00
IUUC-Tgu-116903	Taeniopygia guttata	87.02	0.00e+00	1571.00
IUUC-Tru-118760	Takifugu rubripes	62.51	0.00e+00	1041.00
IUUC-Tsy-119361	Tarsius syrichta	83.96	0.00e+00	1229.00
IUUC-Tbe-127681	Tupaia belangeri	85.80	0.00e+00	1058.00
IUUC-Ttr-128652	Tursiops truncatus	85.17	0.00e+00	1482.00
IUUC-Vpa-130538	Vicugna pacos	83.83	0.00e+00	1459.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence