iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040809

UUCD1 version

UUC-GaG-00786

Ensembl Protein ID

ENSGALP00000037532.3

UniProt Accession

Q8AYA6; F1NXQ8; Q8AYA6_CHICK

Genbank Protein ID

AAN31772.1; AAR97665.1

Protein Name

Suppressor of cytokine signaling 2 variant 1; Suppressor of cytokine signaling 2, variant 1

Genbank Nucleotide ID

AADN04000309; AY509606

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000011295.5	ENSGALT00000038327.4	ENSGALP00000037532.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.00e-12	48.1	112	155

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           ++l ++ +SLqh CR++I++c+ +     i++LPLP +Lk+YL+++ yq
   Q: 112  KPLYTSAPSLQHRCRITINKCTNQ-----IWELPLPTRLKEYLKEYRYQ 155
           5688999***************99.....8***************9886 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MEELRRAGWY WGNMSVAEAK ERLQDAPEGT FLVRDSSHSE YLLTISVKTS AGPTNLRIEY 60
QDGKFRLDSI TCVRSRLKQF NSVVHLIEYY VLMCKDRTET PSNGTVHLYL NKPLYTSAPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTCCCTGC GGAGCGCGGG GGGCGCCGGG CCGCGCTGGG GGCGCCCCGG GGCGGCGGAG 60
GCGGCCGCGC CCGCCGCCGA GGAGTGCCGG GAGGCGGCTC AGCTGGCGGC GGCCATGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	76.10	9.00e-72	262.00
IUUC-Apl-003484	Anas platyrhynchos	99.33	5.00e-87	312.00
IUUC-Aca-004253	Anolis carolinensis	85.53	9.00e-80	288.00
IUUC-Ame-011267	Astyanax mexicanus	59.88	2.00e-54	204.00
IUUC-Bta-013183	Bos taurus	78.29	5.00e-71	259.00
IUUC-Cja-018862	Callithrix jacchus	78.57	7.00e-72	262.00
IUUC-Cfa-020226	Canis familiaris	78.95	9.00e-71	259.00
IUUC-Cpo-022414	Cavia porcellus	79.61	1.00e-71	262.00
IUUC-Csa-023758	Chlorocebus sabaeus	77.92	3.00e-71	260.00
IUUC-Cho-024471	Choloepus hoffmanni	71.97	7.00e-59	219.00
IUUC-Dre-028288	Danio rerio	62.35	3.00e-57	214.00
IUUC-Dno-029036	Dasypus novemcinctus	76.73	1.00e-72	265.00
IUUC-Dor-030447	Dipodomys ordii	78.81	2.00e-70	257.00
IUUC-Ete-033023	Echinops telfairi	77.99	2.00e-73	267.00
IUUC-Fca-036469	Felis catus	77.92	2.00e-71	261.00
IUUC-Fal-036642	Ficedula albicollis	95.39	2.00e-85	307.00
IUUC-Gmo-039331	Gadus morhua	62.07	3.00e-31	126.00
IUUC-Gac-041398	Gasterosteus aculeatus	59.38	2.00e-54	204.00
IUUC-Ggo-045341	Gorilla gorilla	78.57	8.00e-72	262.00
IUUC-Hsa-046557	Homo sapiens	77.36	3.00e-73	266.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	77.42	2.00e-71	261.00
IUUC-Lch-050160	Latimeria chalumnae	62.68	2.00e-49	187.00
IUUC-Loc-051825	Lepisosteus oculatus	61.25	4.00e-58	216.00
IUUC-Laf-053560	Loxodonta africana	77.92	3.00e-71	260.00
IUUC-Mcc-055890	Macaca mulatta	77.27	1.00e-70	258.00
IUUC-Meu-056218	Macropus eugenii	79.25	5.00e-75	273.00
IUUC-Mga-059755	Meleagris gallopavo	100.00	3.00e-87	313.00
IUUC-Mmr-061387	Microcebus murinus	77.92	2.00e-71	260.00
IUUC-Mdo-062383	Monodelphis domestica	80.50	9.00e-76	275.00
IUUC-Mmu-063443	Mus musculus	76.62	4.00e-70	256.00
IUUC-Mpu-066459	Mustela putorius furo	75.97	4.00e-69	253.00
IUUC-Mlu-068040	Myotis lucifugus	76.73	1.00e-72	265.00
IUUC-Nle-069016	Nomascus leucogenys	78.06	1.00e-71	261.00
IUUC-Opr-071087	Ochotona princeps	75.66	9.00e-69	252.00
IUUC-Ont-072340	Oreochromis niloticus	58.43	6.00e-55	206.00
IUUC-Oan-073443	Ornithorhynchus anatinus	81.13	2.00e-76	277.00
IUUC-Ocu-074539	Oryctolagus cuniculus	76.47	5.00e-69	253.00
IUUC-Ola-087004	Oryzias latipes	56.96	3.00e-51	193.00
IUUC-Oga-088438	Otolemur garnettii	77.27	6.00e-71	259.00
IUUC-Oar-089932	Ovis aries	79.61	8.00e-72	262.00
IUUC-Ptr-091037	Pan troglodytes	78.57	8.00e-72	262.00
IUUC-Pan-092767	Papio anubis	77.92	3.00e-71	260.00
IUUC-Psi-093099	Pelodiscus sinensis	89.94	5.00e-82	295.00
IUUC-Pma-094671	Petromyzon marinus	43.33	2.00e-34	138.00
IUUC-Pfo-097073	Poecilia formosa	53.42	2.00e-50	191.00
IUUC-Pab-098319	Pongo abelii	77.36	6.00e-73	266.00
IUUC-Pca-101117	Procavia capensis	77.92	2.00e-70	257.00
IUUC-Pva-102117	Pteropus vampyrus	78.29	3.00e-70	257.00
IUUC-Rno-105913	Rattus norvegicus	75.97	5.00e-69	253.00
IUUC-Sha-106500	Sarcophilus harrisii	79.75	1.00e-74	271.00
IUUC-Ssc-115252	Sus scrofa	78.95	4.00e-71	259.00
IUUC-Tgu-117524	Taeniopygia guttata	96.15	1.00e-87	314.00
IUUC-Tsy-119335	Tarsius syrichta	77.48	3.00e-69	253.00
IUUC-Tni-120263	Tetraodon nigroviridis	56.02	1.00e-52	198.00
IUUC-Tbe-127915	Tupaia belangeri	77.92	5.00e-71	259.00
IUUC-Ttr-128372	Tursiops truncatus	78.95	5.00e-71	259.00
IUUC-Vpa-130422	Vicugna pacos	78.81	2.00e-70	256.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence