iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059216

Ensembl Protein ID

ENSMGAP00000017700.1

UniProt Accession

G3UQ34; G3UQ34_MELGA

Protein Name

Uncharacterized protein

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000010789.2	ENSMGAT00000019929.1	ENSMGAP00000017700.1
ENSMGAG00000010789.2	ENSMGAT00000012107.1	ENSMGAP00000011237.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.00e-16	58.5	402	457

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v++lydy++q+ deL++k+G+ +  i  ee ++gW+kg + l+g  Gl P+n+vek+
   Q: 402  RVRALYDYTGQEADELSFKAGEELMKI-SEEDEQGWCKG-RLLTGHVGLYPANYVEKV 457
           589*********************999.999********.5***************98 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MSSEDDAGGE APEGSFWEAG NYRRTVKRVD DGYRLCNDLI SCFQERAKIE KNYAQQLTEW 60
SRKWRTNVEK GPQYGTLEKA WHAFLTAADK LSEIHLVVRN HLAGEDSDKI KAWQKEAYHK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCTGTTTT ACAGAATTCG AGCTCAGGAC GTAGTTGCCA GCTTCCTGCT GCTCCCCTGT 60
CATCTCGTTT TCAGGTATGT AGCTACTGGG GACTAATGTG GAGTTGCATG CCCTGGAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	62.35	2.00e-180	625.00
IUUC-Apl-003211	Anas platyrhynchos	97.17	0.00e+00	931.00
IUUC-Aca-004256	Anolis carolinensis	84.31	0.00e+00	807.00
IUUC-Ame-011049	Astyanax mexicanus	63.95	2.00e-163	568.00
IUUC-Bta-013322	Bos taurus	65.01	6.00e-174	603.00
IUUC-Cja-018907	Callithrix jacchus	64.27	4.00e-179	620.00
IUUC-Cfa-021126	Canis familiaris	65.14	3.00e-180	624.00
IUUC-Cpo-021491	Cavia porcellus	63.83	1.00e-177	615.00
IUUC-Csa-023107	Chlorocebus sabaeus	64.92	7.00e-180	622.00
IUUC-Cne-026895	Cryptococcus neoformans	42.62	2.00e-09	55.50
IUUC-Dre-027933	Danio rerio	63.18	1.00e-161	561.00
IUUC-Dno-029002	Dasypus novemcinctus	65.36	3.00e-172	597.00
IUUC-Dme-032120	Drosophila melanogaster	41.85	1.00e-102	366.00
IUUC-Eca-033824	Equus caballus	65.36	0.00e+00	629.00
IUUC-Eeu-035122	Erinaceus europaeus	68.42	4.00e-113	400.00
IUUC-Fca-036420	Felis catus	66.45	0.00e+00	635.00
IUUC-Fal-037277	Ficedula albicollis	95.21	0.00e+00	913.00
IUUC-Gga-040941	Gallus gallus	99.34	0.00e+00	946.00
IUUC-Gac-041374	Gasterosteus aculeatus	59.40	3.00e-145	507.00
IUUC-Ggo-045211	Gorilla gorilla	64.71	3.00e-179	620.00
IUUC-Hsa-046053	Homo sapiens	64.92	7.00e-180	622.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	64.92	2.00e-179	621.00
IUUC-Loc-052808	Lepisosteus oculatus	68.85	0.00e+00	632.00
IUUC-Laf-054211	Loxodonta africana	64.72	3.00e-170	590.00
IUUC-Mcc-055044	Macaca mulatta	64.92	7.00e-180	622.00
IUUC-Mmr-061172	Microcebus murinus	64.49	3.00e-180	624.00
IUUC-Mdo-062600	Monodelphis domestica	64.49	0.00e+00	629.00
IUUC-Mmu-063218	Mus musculus	64.27	3.00e-178	617.00
IUUC-Mpu-066819	Mustela putorius furo	60.00	1.00e-177	615.00
IUUC-Mlu-067597	Myotis lucifugus	64.77	3.00e-179	620.00
IUUC-Nle-069195	Nomascus leucogenys	64.27	3.00e-178	617.00
IUUC-Opr-071050	Ochotona princeps	66.23	4.00e-176	610.00
IUUC-Ont-071612	Oreochromis niloticus	59.66	2.00e-154	538.00
IUUC-Oan-073256	Ornithorhynchus anatinus	62.31	3.00e-168	584.00
IUUC-Ocu-074653	Oryctolagus cuniculus	65.36	8.00e-175	605.00
IUUC-Oga-089040	Otolemur garnettii	63.83	5.00e-179	619.00
IUUC-Oar-089918	Ovis aries	64.49	8.00e-176	609.00
IUUC-Ptr-091307	Pan troglodytes	64.92	7.00e-180	622.00
IUUC-Pan-092512	Papio anubis	64.92	7.00e-180	622.00
IUUC-Pfo-096881	Poecilia formosa	60.39	1.00e-156	545.00
IUUC-Pab-098620	Pongo abelii	64.92	7.00e-180	622.00
IUUC-Pva-102464	Pteropus vampyrus	62.75	2.00e-171	595.00
IUUC-Rno-106091	Rattus norvegicus	64.05	1.00e-176	612.00
IUUC-Sha-107474	Sarcophilus harrisii	66.45	0.00e+00	643.00
IUUC-Ssc-116128	Sus scrofa	64.92	4.00e-180	623.00
IUUC-Tgu-117511	Taeniopygia guttata	86.11	0.00e+00	836.00
IUUC-Tru-118005	Takifugu rubripes	63.53	4.00e-155	540.00
IUUC-Tni-119851	Tetraodon nigroviridis	62.08	8.00e-145	506.00
IUUC-Ttr-129313	Tursiops truncatus	66.45	0.00e+00	634.00
IUUC-Vpa-130760	Vicugna pacos	72.68	9.00e-82	296.00
IUUC-Xtr-132697	Xenopus tropicalis	61.10	2.00e-155	541.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence