iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033931

UUCD1 version

UUC-EqC-00700

Ensembl Protein ID

ENSECAP00000009181.1

UniProt Accession

F7B7D0; F7B7D0_HORSE

Protein Name

Uncharacterized protein

Gene Name

TRIM13

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000011381.1	ENSECAT00000011710.1	ENSECAP00000009181.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.40e-08	33.0	12	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C+iC++ f+d p+vlpC H f+++Cl+ +    +  +      f+CP+Cr
   Q: 12   CPICCSLFDD-PRVLPCSHNFCKKCLEGIlegnVRNSLWRLSPFKCPTCR 60
           ********99.**************97774544444444666667****8 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

DVMELLEEDL TCPICCSLFD DPRVLPCSHN FCKKCLEGIL EGNVRNSLWR LSPFKCPTCR 60
KETSATGVNS LQVNYSLKGI VEKYNKIKIS PKMPVCKGHL GQPLNIFCLT DMQLICGICA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAAACTAA AACCGATTGC TTTGCCCTGG GAAATAGTAA CCCTGACGCA TACACCTGCT 60
TGCAGGGGAC AGAGGTAAAC TACAATATTT TTTCCTACAT TAAAAAAACC AGAAAACAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0097038--C:perinuclear endoplasmic reticulum
GO:0004871--F:signal transducer activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0010942--P:positive regulation of cell death
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0016239--P:positive regulation of macroautophagy
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0051865--P:protein autoubiquitination
GO:0010332--P:response to gamma radiation
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002269	Ailuropoda melanoleuca	96.58	0.00e+00	749.00
IUUC-Apl-004168	Anas platyrhynchos	75.98	2.00e-180	624.00
IUUC-Aca-004395	Anolis carolinensis	69.85	6.00e-165	573.00
IUUC-Ame-011325	Astyanax mexicanus	46.13	3.00e-67	248.00
IUUC-Bta-012613	Bos taurus	94.84	0.00e+00	733.00
IUUC-Cja-018856	Callithrix jacchus	94.13	0.00e+00	794.00
IUUC-Cfa-021019	Canis familiaris	95.11	0.00e+00	741.00
IUUC-Cpo-021845	Cavia porcellus	92.87	0.00e+00	721.00
IUUC-Csa-023380	Chlorocebus sabaeus	93.37	0.00e+00	734.00
IUUC-Cho-024733	Choloepus hoffmanni	85.52	2.00e-92	332.00
IUUC-Dre-028675	Danio rerio	49.15	2.00e-110	392.00
IUUC-Dno-030018	Dasypus novemcinctus	92.40	0.00e+00	742.00
IUUC-Dor-030599	Dipodomys ordii	92.51	1.00e-132	465.00
IUUC-Ete-033134	Echinops telfairi	89.02	0.00e+00	726.00
IUUC-Eeu-034903	Erinaceus europaeus	92.91	0.00e+00	726.00
IUUC-Fca-035642	Felis catus	96.31	0.00e+00	731.00
IUUC-Fal-037108	Ficedula albicollis	76.72	0.00e+00	638.00
IUUC-Gga-040903	Gallus gallus	75.00	1.00e-179	622.00
IUUC-Ggo-044635	Gorilla gorilla	93.64	0.00e+00	739.00
IUUC-Hsa-046345	Homo sapiens	93.64	0.00e+00	740.00
IUUC-Itr-048220	Ictidomys tridecemlineatus	92.20	0.00e+00	704.00
IUUC-Lch-050599	Latimeria chalumnae	60.74	2.00e-138	485.00
IUUC-Loc-052378	Lepisosteus oculatus	63.07	8.00e-117	412.00
IUUC-Laf-053332	Loxodonta africana	93.63	0.00e+00	729.00
IUUC-Mcc-054705	Macaca mulatta	93.15	0.00e+00	736.00
IUUC-Meu-056825	Macropus eugenii	84.88	0.00e+00	717.00
IUUC-Mga-059528	Meleagris gallopavo	75.00	0.00e+00	633.00
IUUC-Mmr-060688	Microcebus murinus	95.84	0.00e+00	741.00
IUUC-Mdo-061882	Monodelphis domestica	84.11	0.00e+00	720.00
IUUC-Mmu-064352	Mus musculus	89.68	0.00e+00	740.00
IUUC-Mpu-066712	Mustela putorius furo	97.07	0.00e+00	686.00
IUUC-Mlu-068093	Myotis lucifugus	94.59	0.00e+00	723.00
IUUC-Nle-069310	Nomascus leucogenys	93.61	0.00e+00	732.00
IUUC-Ont-071759	Oreochromis niloticus	59.61	8.00e-112	396.00
IUUC-Oan-073673	Ornithorhynchus anatinus	80.24	0.00e+00	689.00
IUUC-Ocu-074192	Oryctolagus cuniculus	94.13	0.00e+00	743.00
IUUC-Ola-087424	Oryzias latipes	58.77	2.00e-109	389.00
IUUC-Oga-088808	Otolemur garnettii	95.09	0.00e+00	742.00
IUUC-Oar-089553	Ovis aries	94.87	0.00e+00	736.00
IUUC-Ptr-090518	Pan troglodytes	93.40	0.00e+00	736.00
IUUC-Pan-092781	Papio anubis	92.91	0.00e+00	734.00
IUUC-Psi-093914	Pelodiscus sinensis	75.06	1.00e-180	625.00
IUUC-Ppa-095862	Physcomitrella patens	36.99	2.00e-06	45.40
IUUC-Pfo-096346	Poecilia formosa	56.08	3.00e-110	391.00
IUUC-Pca-100914	Procavia capensis	90.73	0.00e+00	738.00
IUUC-Pva-102728	Pteropus vampyrus	95.84	0.00e+00	739.00
IUUC-Rno-105922	Rattus norvegicus	88.94	0.00e+00	674.00
IUUC-Sha-107124	Sarcophilus harrisii	84.84	0.00e+00	728.00
IUUC-Sar-113607	Sorex araneus	90.95	0.00e+00	704.00
IUUC-Ssc-116355	Sus scrofa	96.31	0.00e+00	742.00
IUUC-Tgu-116476	Taeniopygia guttata	76.47	0.00e+00	635.00
IUUC-Tru-118737	Takifugu rubripes	60.26	2.00e-113	402.00
IUUC-Tsy-118908	Tarsius syrichta	95.11	0.00e+00	764.00
IUUC-Tbe-127258	Tupaia belangeri	97.80	0.00e+00	754.00
IUUC-Vpa-130138	Vicugna pacos	95.11	0.00e+00	743.00
IUUC-Xtr-132100	Xenopus tropicalis	59.51	8.00e-135	473.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence