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Tag Content
iUUCD ID IUUC-Cfa-020953
Ensembl Protein ID ENSCAFP00000017728.3
UniProt Accession E2RSY7; E2RSY7_CANLF
Genbank Protein ID ENSCAFP00000017728
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03012231
Gene Name ARIH2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000012041.4 ENSCAFT00000019122.4 ENSCAFP00000017728.3
ENSCAFG00000012041.4 ENSCAFT00000019133.3 ENSCAFP00000017739.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RBR 1.30e-55 188.9 137 324
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RBR
   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C+vC+ ++  +e++ +l+C+h+fC++C++q++++ +k+g  + +sc+a++cp +++e+ +  ll++eel ++y+++l++++ve++++l++
   Q: 137  CAVCM-QFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELRDKYRRYLFRDYVESHYQLQL 225
           9***9.77777888899************************************************************************* PP
   S: 91   cpapdCslvvllekeaeklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyieknegCnhm 180
           cp +dC +v+++++  ++ +v+c++c+++fC++C++++H++++C +++++l+k++   +++e++++++a++k+CpkC+++iekn+gCnhm
   Q: 226  CPGADCPMVIRVQEP-RARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCA---DDSETANYISAHTKDCPKCNICIEKNGGCNHM 311
           **************7.99*************************************...99****************************** PP
   S: 181  tCakCkaefCwlC 193
           +C+kCk++fCw+C
   Q: 312  QCSKCKHDFCWMC 324
           ************* PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MSVDMNSQGS DSNEEDYDPN CEEEEEDEDP GDIEDYYVGV ASDVEQQGAD AFDPEEYQFT 60
CLTYKESEGA LNEHMTSLAS VLKVSHSVAK LILVNFHWQV AEILDRYKSN SAQLLVEARV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-020953|E3,RBR|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGAAATTA TGTGACATAG AATATTTGGG GTGACATCTG GAAAGATCTT CAAGCATTAC 60
AGGTATTTTT ATTTTAAAGA TTAACTTTTT CTTCTAAAGG AGAAGTACCG TACTTCATTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-020953|E3,RBR|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF01485--IBR
SMART

SM00647--IBR
SM00184--RING
Gene Ontology

GO:0031466--C:Cul5-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0048588--P:developmental cell growth
GO:0071425--P:hematopoietic stem cell proliferation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0070936--P:protein K48-linked ubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001557 Ailuropoda melanoleuca 99.80 0.00e+00 947.00
IUUC-Apl-003878 Anas platyrhynchos 93.89 0.00e+00 882.00
IUUC-Aca-004865 Anolis carolinensis 93.08 0.00e+00 887.00
IUUC-Bta-012901 Bos taurus 99.19 0.00e+00 939.00
IUUC-Cel-018334 Caenorhabditis elegans 48.64 1.00e-126 446.00
IUUC-Cja-019728 Callithrix jacchus 96.95 0.00e+00 935.00
IUUC-Cpo-021445 Cavia porcellus 97.15 0.00e+00 937.00
IUUC-Csa-023769 Chlorocebus sabaeus 96.96 0.00e+00 936.00
IUUC-Cho-024650 Choloepus hoffmanni 86.21 0.00e+00 790.00
IUUC-Cin-025577 Ciona intestinalis 54.55 5.00e-144 504.00
IUUC-Csv-025849 Ciona savignyi 55.58 2.00e-119 422.00
IUUC-Dre-028490 Danio rerio 80.36 0.00e+00 783.00
IUUC-Dno-029942 Dasypus novemcinctus 96.55 0.00e+00 929.00
IUUC-Dor-030134 Dipodomys ordii 85.30 2.00e-151 528.00
IUUC-Dme-031853 Drosophila melanogaster 55.70 5.00e-151 527.00
IUUC-Ete-032355 Echinops telfairi 89.07 0.00e+00 835.00
IUUC-Eca-033440 Equus caballus 99.59 0.00e+00 944.00
IUUC-Eeu-035230 Erinaceus europaeus 89.36 2.00e-115 408.00
IUUC-Fca-036308 Felis catus 93.29 0.00e+00 874.00
IUUC-Fal-036974 Ficedula albicollis 93.89 0.00e+00 882.00
IUUC-Gmo-038642 Gadus morhua 81.71 0.00e+00 782.00
IUUC-Gga-041019 Gallus gallus 93.89 0.00e+00 882.00
IUUC-Gac-042014 Gasterosteus aculeatus 80.08 0.00e+00 803.00
IUUC-Ggo-045329 Gorilla gorilla 97.36 0.00e+00 937.00
IUUC-Hsa-046712 Homo sapiens 97.16 0.00e+00 937.00
IUUC-Itr-048370 Ictidomys tridecemlineatus 98.80 0.00e+00 842.00
IUUC-Lch-049584 Latimeria chalumnae 85.77 0.00e+00 819.00
IUUC-Loc-051826 Lepisosteus oculatus 79.62 1.00e-164 572.00
IUUC-Laf-054567 Loxodonta africana 97.35 0.00e+00 916.00
IUUC-Mcc-054919 Macaca mulatta 96.96 0.00e+00 936.00
IUUC-Meu-056332 Macropus eugenii 89.05 0.00e+00 847.00
IUUC-Mga-060132 Meleagris gallopavo 94.12 0.00e+00 888.00
IUUC-Mmr-061599 Microcebus murinus 93.12 0.00e+00 881.00
IUUC-Mdo-062186 Monodelphis domestica 95.17 0.00e+00 803.00
IUUC-Mmu-064271 Mus musculus 96.54 0.00e+00 932.00
IUUC-Mpu-066827 Mustela putorius furo 97.62 0.00e+00 834.00
IUUC-Mlu-067528 Myotis lucifugus 98.78 0.00e+00 900.00
IUUC-Nle-068995 Nomascus leucogenys 97.36 0.00e+00 937.00
IUUC-Opr-070518 Ochotona princeps 96.96 0.00e+00 897.00
IUUC-Ont-071650 Oreochromis niloticus 83.27 0.00e+00 822.00
IUUC-Oan-073676 Ornithorhynchus anatinus 94.12 0.00e+00 755.00
IUUC-Ocu-073761 Oryctolagus cuniculus 97.77 0.00e+00 940.00
IUUC-Obr-076705 Oryza brachyantha 29.59 1.00e-57 218.00
IUUC-Ola-087204 Oryzias latipes 79.96 0.00e+00 797.00
IUUC-Oga-088098 Otolemur garnettii 96.96 0.00e+00 930.00
IUUC-Oar-089205 Ovis aries 99.19 0.00e+00 939.00
IUUC-Ptr-091514 Pan troglodytes 97.36 0.00e+00 937.00
IUUC-Pan-092493 Papio anubis 92.25 0.00e+00 890.00
IUUC-Psi-093024 Pelodiscus sinensis 88.58 1.00e-119 422.00
IUUC-Pfo-097256 Poecilia formosa 82.24 0.00e+00 812.00
IUUC-Pab-098504 Pongo abelii 89.66 0.00e+00 837.00
IUUC-Pop-099547 Populus trichocarpa 30.85 3.00e-55 209.00
IUUC-Pca-100700 Procavia capensis 89.66 0.00e+00 832.00
IUUC-Pva-103105 Pteropus vampyrus 98.57 0.00e+00 929.00
IUUC-Rno-105289 Rattus norvegicus 96.75 0.00e+00 934.00
IUUC-Sha-107417 Sarcophilus harrisii 93.31 0.00e+00 868.00
IUUC-Ssl-108406 Sclerotinia sclerotiorum 23.30 3.00e-07 50.10
IUUC-Sar-113042 Sorex araneus 96.38 0.00e+00 927.00
IUUC-Ssc-115362 Sus scrofa 99.39 0.00e+00 942.00
IUUC-Tgu-117469 Taeniopygia guttata 93.59 0.00e+00 834.00
IUUC-Tru-117976 Takifugu rubripes 80.98 0.00e+00 816.00
IUUC-Tsy-118876 Tarsius syrichta 83.56 4.00e-92 331.00
IUUC-Tni-119831 Tetraodon nigroviridis 80.39 0.00e+00 798.00
IUUC-Tca-121326 Theobroma cacao 28.91 5.00e-59 222.00
IUUC-Tbe-127386 Tupaia belangeri 89.38 1.00e-159 556.00
IUUC-Ttr-128315 Tursiops truncatus 99.19 0.00e+00 941.00
IUUC-Vpa-130383 Vicugna pacos 92.26 0.00e+00 847.00
IUUC-Xtr-132945 Xenopus tropicalis 89.23 0.00e+00 874.00
Created Date 25-Jun-2017

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