iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093391

Ensembl Protein ID

ENSPSIP00000013243.1

UniProt Accession

K7FYY3; K7FYY3_PELSI

Genbank Protein ID

ENSPSIP00000013243

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01170109

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000011851.1	ENSPSIT00000013306.1	ENSPSIP00000013243.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.70e-19	70.0	29	92
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.40e-13	49.8	128	158

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l v+++ f ah+ivLaa+S++F a+f++el+e++ k+ v+i+++ ++ ++ ll+F+Yt ++
   Q: 29   CDVTLRVEQKDFAAHRIVLAACSDYFCAMFTSELSEKD-KPYVDIQGLTASTMEILLDFVYTETV 92
           9************************************9.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++fA++++c dL++aa+ f +khF
   Q: 128  PSNCLGIRDFAETHNCIDLMQAAEVFSQKHF 158
           89***************************** PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MAPKDIMTNS HAKSILNAMN ALRRSSTLCD VTLRVEQKDF AAHRIVLAAC SDYFCAMFTS 60
ELSEKDKPYV DIQGLTASTM EILLDFVYTE TVHVTVENVQ ELLPAACLLQ LKGVKQACCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNGAG 60
CAGGGCCTGG GAGCAGAGCC TGTCCCCCTG CCCCATCCCG TGCTGGGAGA ACAGGGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0005815--C:microtubule organizing center
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination
GO:0016055--P:Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	95.36	0.00e+00	1094.00
IUUC-Apl-003339	Anas platyrhynchos	98.84	0.00e+00	1045.00
IUUC-Aca-004418	Anolis carolinensis	97.70	0.00e+00	1125.00
IUUC-Ath-007066	Arabidopsis thaliana	33.68	2.00e-40	160.00
IUUC-Ame-011906	Astyanax mexicanus	74.56	0.00e+00	872.00
IUUC-Bta-012979	Bos taurus	94.15	0.00e+00	1094.00
IUUC-Cja-019582	Callithrix jacchus	95.39	0.00e+00	1107.00
IUUC-Cfa-020716	Canis familiaris	95.92	0.00e+00	1114.00
IUUC-Cpo-022013	Cavia porcellus	96.10	0.00e+00	1116.00
IUUC-Csa-023424	Chlorocebus sabaeus	95.79	0.00e+00	1031.00
IUUC-Cho-024586	Choloepus hoffmanni	78.37	0.00e+00	870.00
IUUC-Dre-028344	Danio rerio	88.03	1.00e-165	575.00
IUUC-Dno-028854	Dasypus novemcinctus	95.92	0.00e+00	1114.00
IUUC-Dor-030403	Dipodomys ordii	95.74	0.00e+00	1111.00
IUUC-Ete-032963	Echinops telfairi	94.63	0.00e+00	971.00
IUUC-Eca-033282	Equus caballus	95.74	0.00e+00	1114.00
IUUC-Eeu-034933	Erinaceus europaeus	96.08	8.00e-141	493.00
IUUC-Fca-035487	Felis catus	95.92	0.00e+00	1114.00
IUUC-Fal-037059	Ficedula albicollis	98.22	0.00e+00	1120.00
IUUC-Gmo-039564	Gadus morhua	89.01	0.00e+00	1074.00
IUUC-Gga-040629	Gallus gallus	98.22	0.00e+00	1126.00
IUUC-Gac-042526	Gasterosteus aculeatus	89.36	0.00e+00	1077.00
IUUC-Ggo-044839	Gorilla gorilla	95.92	0.00e+00	1114.00
IUUC-Hsa-046742	Homo sapiens	95.92	0.00e+00	1114.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	95.74	0.00e+00	1111.00
IUUC-Lch-049540	Latimeria chalumnae	92.20	0.00e+00	1108.00
IUUC-Loc-051923	Lepisosteus oculatus	92.55	0.00e+00	1082.00
IUUC-Laf-054370	Loxodonta africana	95.74	0.00e+00	1113.00
IUUC-Mcc-054852	Macaca mulatta	95.92	0.00e+00	1114.00
IUUC-Mga-059486	Meleagris gallopavo	97.26	0.00e+00	1034.00
IUUC-Mvi-060512	Microbotryum violaceum	21.67	1.00e-05	45.40
IUUC-Mmr-061777	Microcebus murinus	95.92	0.00e+00	1113.00
IUUC-Mdo-061990	Monodelphis domestica	95.57	0.00e+00	1110.00
IUUC-Mmu-064053	Mus musculus	95.39	0.00e+00	1112.00
IUUC-Mac-064654	Musa acuminata	34.02	1.00e-41	164.00
IUUC-Mpu-066623	Mustela putorius furo	81.97	0.00e+00	784.00
IUUC-Mlu-067648	Myotis lucifugus	95.21	0.00e+00	1135.00
IUUC-Nle-069714	Nomascus leucogenys	95.74	0.00e+00	1113.00
IUUC-Opr-071143	Ochotona princeps	89.54	0.00e+00	1018.00
IUUC-Ont-071848	Oreochromis niloticus	90.25	0.00e+00	1087.00
IUUC-Oan-073041	Ornithorhynchus anatinus	93.53	1.00e-156	545.00
IUUC-Ocu-074379	Oryctolagus cuniculus	96.10	0.00e+00	1117.00
IUUC-Oin-079973	Oryza indica	32.48	7.00e-35	141.00
IUUC-Ola-087469	Oryzias latipes	89.89	0.00e+00	1084.00
IUUC-Oar-090144	Ovis aries	95.21	0.00e+00	1107.00
IUUC-Ptr-091406	Pan troglodytes	95.92	0.00e+00	1114.00
IUUC-Pan-092762	Papio anubis	94.87	0.00e+00	1095.00
IUUC-Pma-094134	Petromyzon marinus	74.18	0.00e+00	831.00
IUUC-Pfo-096404	Poecilia formosa	90.07	0.00e+00	1083.00
IUUC-Pab-098425	Pongo abelii	95.04	0.00e+00	1102.00
IUUC-Pca-101093	Procavia capensis	95.17	1.00e-166	579.00
IUUC-Pva-102239	Pteropus vampyrus	85.99	0.00e+00	996.00
IUUC-Rno-104921	Rattus norvegicus	95.57	0.00e+00	1113.00
IUUC-Sha-106625	Sarcophilus harrisii	96.45	0.00e+00	1118.00
IUUC-Sar-113468	Sorex araneus	83.67	0.00e+00	685.00
IUUC-Ssc-116106	Sus scrofa	95.57	0.00e+00	1111.00
IUUC-Tgu-117402	Taeniopygia guttata	74.95	0.00e+00	754.00
IUUC-Tru-117546	Takifugu rubripes	89.36	0.00e+00	1079.00
IUUC-Tsy-118802	Tarsius syrichta	86.17	0.00e+00	970.00
IUUC-Tni-119999	Tetraodon nigroviridis	89.82	0.00e+00	1075.00
IUUC-Tca-121074	Theobroma cacao	31.48	6.00e-39	155.00
IUUC-Tbe-127987	Tupaia belangeri	95.22	0.00e+00	928.00
IUUC-Ttr-128613	Tursiops truncatus	88.45	0.00e+00	1006.00
IUUC-Xtr-132401	Xenopus tropicalis	91.26	1.00e-172	598.00
IUUC-Xma-134289	Xiphophorus maculatus	90.07	0.00e+00	1083.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence