iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037189

Ensembl Protein ID

ENSFALP00000008709.1

UniProt Accession

U3K105; U3K105_FICAL

Genbank Protein ID

ENSFALP00000008709

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01011210

Gene Name

RFWD2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000008359.1	ENSFALT00000008747.1	ENSFALP00000008709.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.90e-25	85.6	348	377
E3 activity/RING/RING	1.30e-06	28.5	14	52

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 348  NSKISCISWssYHkNLLASSDYEGTVILWD 377
           689******9622599************** PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 14   CPICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 52
           ********99.888***********9555......999999****6 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MFKMFEVFPA EKECPICFDM IEEAYMTKCG HSFCYKCIHQ SLEDNNRCPK CNYVVDNIDH 60
LYPNFLVNEL ILKQKQRSEE KRLKLDHSVS STNGHRWQII QDLLGTDQDN LDLANVNLML 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGATTAGAC CAGGGAGGAG CTGAATAGGA GGCAGGCACT GTAATGAATC TTGTTTGCTG 60
TTGAAGTGTG TTTAAATTTC ATAGTGACCA CTTCAGCCAG GTGTTTGTGT AGCAGTAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	40.19	2.00e-127	449.00
IUUC-Aml-001265	Ailuropoda melanoleuca	98.82	0.00e+00	1187.00
IUUC-Atr-002460	Amborella trichopoda	38.64	2.00e-123	436.00
IUUC-Apl-003796	Anas platyrhynchos	99.14	0.00e+00	1168.00
IUUC-Aca-005078	Anolis carolinensis	97.99	0.00e+00	1163.00
IUUC-Aly-006014	Arabidopsis lyrata	39.94	4.00e-129	454.00
IUUC-Ath-007636	Arabidopsis thaliana	39.78	3.00e-128	452.00
IUUC-Ame-011176	Astyanax mexicanus	96.69	1.00e-69	257.00
IUUC-Bta-012595	Bos taurus	98.83	0.00e+00	1194.00
IUUC-Bdi-014152	Brachypodium distachyon	39.29	3.00e-128	452.00
IUUC-Bol-016380	Brassica oleracea	40.62	3.00e-129	455.00
IUUC-Bra-017690	Brassica rapa	39.47	8.00e-124	437.00
IUUC-Cja-018926	Callithrix jacchus	98.66	0.00e+00	1191.00
IUUC-Cfa-021088	Canis familiaris	98.66	0.00e+00	1195.00
IUUC-Cpo-022442	Cavia porcellus	97.60	0.00e+00	1150.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	33.45	3.00e-33	135.00
IUUC-Csa-024119	Chlorocebus sabaeus	98.32	0.00e+00	1187.00
IUUC-Cho-024883	Choloepus hoffmanni	66.23	5.00e-106	378.00
IUUC-Cin-025375	Ciona intestinalis	56.13	0.00e+00	665.00
IUUC-Cme-027350	Cyanidioschyzon merolae	40.78	1.00e-79	291.00
IUUC-Dre-028453	Danio rerio	88.37	0.00e+00	1058.00
IUUC-Dno-029887	Dasypus novemcinctus	98.32	0.00e+00	1189.00
IUUC-Dor-031110	Dipodomys ordii	79.83	0.00e+00	925.00
IUUC-Ete-033016	Echinops telfairi	83.56	0.00e+00	978.00
IUUC-Eca-034403	Equus caballus	98.27	0.00e+00	1152.00
IUUC-Eeu-034690	Erinaceus europaeus	81.34	0.00e+00	954.00
IUUC-Fca-036475	Felis catus	97.76	0.00e+00	1154.00
IUUC-Gmo-039245	Gadus morhua	87.21	0.00e+00	1035.00
IUUC-Gga-040806	Gallus gallus	99.66	0.00e+00	1204.00
IUUC-Gac-042177	Gasterosteus aculeatus	88.81	0.00e+00	1075.00
IUUC-Gma-044187	Glycine max	40.65	2.00e-125	442.00
IUUC-Ggo-044430	Gorilla gorilla	97.32	0.00e+00	870.00
IUUC-Hsa-045853	Homo sapiens	98.49	0.00e+00	1188.00
IUUC-Hvu-047750	Hordeum vulgare	39.34	1.00e-95	344.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	98.75	3.00e-143	499.00
IUUC-Lch-050420	Latimeria chalumnae	92.04	0.00e+00	1103.00
IUUC-Lpe-051219	Leersia perrieri	38.88	7.00e-124	437.00
IUUC-Loc-052728	Lepisosteus oculatus	91.51	0.00e+00	1076.00
IUUC-Laf-053775	Loxodonta africana	97.97	0.00e+00	1190.00
IUUC-Meu-056595	Macropus eugenii	77.70	2.00e-177	615.00
IUUC-Mtr-058555	Medicago truncatula	40.83	5.00e-133	468.00
IUUC-Mga-059646	Meleagris gallopavo	99.14	0.00e+00	1166.00
IUUC-Mmr-060990	Microcebus murinus	98.82	0.00e+00	1188.00
IUUC-Mdo-062287	Monodelphis domestica	98.83	0.00e+00	1195.00
IUUC-Mmu-064097	Mus musculus	98.49	0.00e+00	1191.00
IUUC-Mac-065240	Musa acuminata	41.54	4.00e-135	474.00
IUUC-Mpu-066612	Mustela putorius furo	97.77	0.00e+00	1158.00
IUUC-Mlu-067967	Myotis lucifugus	95.98	0.00e+00	1157.00
IUUC-Nle-069543	Nomascus leucogenys	98.66	0.00e+00	1191.00
IUUC-Opr-070366	Ochotona princeps	83.13	0.00e+00	668.00
IUUC-Ont-071522	Oreochromis niloticus	88.31	0.00e+00	1063.00
IUUC-Oan-073409	Ornithorhynchus anatinus	98.28	0.00e+00	1155.00
IUUC-Ocu-073756	Oryctolagus cuniculus	98.26	0.00e+00	1156.00
IUUC-Oba-075149	Oryza barthii	39.07	2.00e-126	447.00
IUUC-Obr-076563	Oryza brachyantha	39.41	7.00e-127	447.00
IUUC-Ogl-077701	Oryza glaberrima	39.04	5.00e-127	447.00
IUUC-Ogu-078383	Oryza glumaepatula	39.04	5.00e-127	447.00
IUUC-Oin-079965	Oryza indica	37.18	2.00e-114	406.00
IUUC-Olo-080639	Oryza longistaminata	38.78	6.00e-125	441.00
IUUC-Ome-081821	Oryza meridionalis	38.83	1.00e-115	410.00
IUUC-Oni-082622	Oryza nivara	39.04	5.00e-127	447.00
IUUC-Opu-083295	Oryza punctata	39.04	1.00e-126	446.00
IUUC-Oru-084661	Oryza rufipogon	39.04	5.00e-127	447.00
IUUC-Osa-085766	Oryza sativa	39.04	5.00e-127	447.00
IUUC-Ola-086727	Oryzias latipes	88.48	0.00e+00	1081.00
IUUC-Olu-087702	Ostreococcus lucimarinus	42.99	2.00e-69	254.00
IUUC-Oga-088215	Otolemur garnettii	96.47	0.00e+00	1163.00
IUUC-Oar-089880	Ovis aries	98.62	0.00e+00	1158.00
IUUC-Ptr-090597	Pan troglodytes	98.49	0.00e+00	1188.00
IUUC-Pan-091987	Papio anubis	98.83	0.00e+00	1194.00
IUUC-Psi-094033	Pelodiscus sinensis	98.31	0.00e+00	1169.00
IUUC-Pma-094587	Petromyzon marinus	70.54	0.00e+00	773.00
IUUC-Ppa-095256	Physcomitrella patens	38.83	3.00e-132	465.00
IUUC-Pfo-097388	Poecilia formosa	87.44	0.00e+00	1042.00
IUUC-Pab-098029	Pongo abelii	98.49	0.00e+00	1189.00
IUUC-Pop-099319	Populus trichocarpa	39.04	2.00e-129	456.00
IUUC-Pca-100846	Procavia capensis	89.77	0.00e+00	1081.00
IUUC-Ppe-101250	Prunus persica	39.03	2.00e-118	419.00
IUUC-Pva-102407	Pteropus vampyrus	98.49	0.00e+00	1179.00
IUUC-Rno-105312	Rattus norvegicus	98.49	0.00e+00	1189.00
IUUC-Sha-106514	Sarcophilus harrisii	98.92	0.00e+00	773.00
IUUC-Smo-109418	Selaginella moellendorffii	40.75	5.00e-130	457.00
IUUC-Sit-110248	Setaria italica	38.78	3.00e-128	452.00
IUUC-Sly-110964	Solanum lycopersicum	40.62	2.00e-131	462.00
IUUC-Stu-112882	Solanum tuberosum	40.77	1.00e-131	463.00
IUUC-Sar-113230	Sorex araneus	71.69	0.00e+00	801.00
IUUC-Sbi-113962	Sorghum bicolor	37.06	7.00e-123	434.00
IUUC-Ssc-115987	Sus scrofa	97.59	2.00e-159	555.00
IUUC-Tgu-116471	Taeniopygia guttata	99.83	0.00e+00	1198.00
IUUC-Tru-118231	Takifugu rubripes	87.79	0.00e+00	1028.00
IUUC-Tsy-119415	Tarsius syrichta	97.82	0.00e+00	1164.00
IUUC-Tni-120893	Tetraodon nigroviridis	87.96	0.00e+00	1036.00
IUUC-Tca-121703	Theobroma cacao	41.49	5.00e-130	457.00
IUUC-Tae-125440	Triticum aestivum	41.27	6.00e-134	471.00
IUUC-Tur-126557	Triticum urartu	40.72	2.00e-130	459.00
IUUC-Tbe-127253	Tupaia belangeri	69.97	0.00e+00	800.00
IUUC-Ttr-129100	Tursiops truncatus	96.47	0.00e+00	1132.00
IUUC-Vpa-130613	Vicugna pacos	91.76	0.00e+00	1089.00
IUUC-Vvi-130880	Vitis vinifera	41.06	9.00e-124	437.00
IUUC-Xtr-132033	Xenopus tropicalis	95.97	0.00e+00	1189.00
IUUC-Xma-133421	Xiphophorus maculatus	87.27	0.00e+00	1039.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence