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Tag Content
UUCD2 ID IUUC-Mcc-055473
UUCD1 version UUC-MaM-01129
Ensembl Protein ID ENSMMUP00000031314.3
UniProt Accession F7GVG4; F7GVG4_MACMU
Genbank Protein ID ENSMMUP00000031314
Protein Name Uncharacterized protein
Genbank Nucleotide ID JSUE03013443
Gene Name USP28
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMMUG00000023773.3 ENSMMUT00000033459.3 ENSMMUP00000031315.2
ENSMMUG00000023773.3 ENSMMUT00000074150.1 ENSMMUP00000046380.1
ENSMMUG00000023773.3 ENSMMUT00000033458.3 ENSMMUP00000031314.3
ENSMMUG00000023773.3 ENSMMUT00000057478.1 ENSMMUP00000044785.1
ENSMMUG00000023773.3 ENSMMUT00000075903.1 ENSMMUP00000051976.1
ENSMMUG00000023773.3 ENSMMUT00000069785.1 ENSMMUP00000059782.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 2.00e-58 199.3 162 648
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +GlkN+gNtC++ +v+Q+L+++pe+r+l+l+     +  e+++    ++++  ++++lq lf+ ++ s++k v+p++ l+ lk + ++ 
   Q: 162  VGLKNVGNTCWFSAVIQSLFQLPEFRRLVLSynlpqNVLENCRSH-TEKRNIMFMQELQYLFALMMGSNRKFVDPSAALDLLKGAFRS- 248
           6******************************96665445555443.478888*******************************99987. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
           s+ +qqD++Ef++ lld le++++                     + +++ +k+++++++lF g++ ++ + +        +e+f +++
   Q: 249  SEEQQQDVSEFTHKLLDWLEDAFQL------------------AVNVNSPRNKSENPMVQLFYGTFLTEGVREGKPFC--NNETFGQYP 317
           99*********************22..................23467899****************99998665555..5899***** PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e  +e    +  +   ++++  ++ +++klP+vL+++L+Rf+f+++ +++eki++k+efp+ + ++
   Q: 318  LQVNGYR-----NLDECLEGAMVEGDVE----LLPSD--HSVKYGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHNKLEFPQIIYMD 395
           *******.....99****7665555555....55554..556778899***************************************** PP
   S: 263  pfcts.................................................................................... 267
           +++ +                                                                                    
   Q: 396  RYMYRskelirnkrecirklkeeikilqqkleryvkygsgparfplpdmlkyviefastkpasescppesdthmtlplssvhcpvsdqt 484
           *9999778888888777777777777777777777777777777777777777777777777777776666666666666666666555 PP
   S: 268  .peekqke................................................................................. 274
            +     e                                                                                 
   Q: 485  sK-----Eststesssldvestfsspedslhkskpltssrssmempaqpaprtvtdeeinfvktclqrwrseieqdiqdlknciasttq 568
           50.....0455556666666666666677777777777777888888888888888888888888888888888889999999999999 PP
   S: 275  ............kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                       ++ Y+L+av+vH+G+++ GHY+ay++n+ ++ Wl+++D +Vte+++eev++++       +aY+l+Y 
   Q: 569  tieqmycdpllrQVPYRLHAVLVHEGQANAGHYWAYIYNQPRQsWLKYNDISVTESSWEEVERDSYgglrnVSAYCLMYI 648
           999999****99***************************88888*******************8879************6 PP
   
Organism Macaca mulatta
Protein Sequence
(Fasta)
MTAELQQDDA AGAADGHSSS CQMLLNQLRE ITGIQDPSFL HEALKASNGD ITQAVSLLTD 60
ERVKEPSQDT VATEPSEVEG SAANKEVLAK VIDLTHDNKD DLQAAIALSL LESPKIQADG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mcc-055473|DUB,USP|Macaca mulatta
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGAGGCTGG GCCGGCGGTG GCAGCGGCGG GAGACGGGTG ACCCGCGGCT GGGCGCCTCG 60
GCCATGACTG CGGAGCTGCA GCAGGACGAC GCGGCCGGCG CGGCCGACGG CCACAGCTCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mcc-055473|DUB,USP|Macaca mulatta
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR011990--TPR-like_helical_dom
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0016604--C:nuclear body
GO:0043234--C:protein complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008283--P:cell proliferation
GO:0034644--P:cellular response to UV
GO:0000077--P:DNA damage checkpoint
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0007265--P:Ras protein signal transduction
GO:0031647--P:regulation of protein stability
GO:0010212--P:response to ionizing radiation
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001836 Ailuropoda melanoleuca 92.72 0.00e+00 1394.00
IUUC-Apl-004010 Anas platyrhynchos 65.18 0.00e+00 1400.00
IUUC-Aca-004741 Anolis carolinensis 61.23 0.00e+00 1342.00
IUUC-Acl-008164 Aspergillus clavatus 23.21 5.00e-15 77.40
IUUC-Ani-009503 Aspergillus nidulans 35.85 8.00e-11 63.20
IUUC-Ang-009577 Aspergillus niger 36.36 2.00e-11 65.10
IUUC-Ate-010275 Aspergillus terreus 35.24 4.00e-11 64.30
IUUC-Ame-011910 Astyanax mexicanus 44.05 8.00e-179 622.00
IUUC-Bta-013377 Bos taurus 90.96 0.00e+00 1334.00
IUUC-Cja-019977 Callithrix jacchus 98.18 0.00e+00 1450.00
IUUC-Cfa-020378 Canis familiaris 94.65 0.00e+00 2103.00
IUUC-Cpo-021817 Cavia porcellus 88.23 0.00e+00 1316.00
IUUC-Csa-023446 Chlorocebus sabaeus 99.82 0.00e+00 2231.00
IUUC-Cho-024717 Choloepus hoffmanni 81.45 0.00e+00 670.00
IUUC-Cme-027167 Cyanidioschyzon merolae 33.00 8.00e-16 79.70
IUUC-Dor-030955 Dipodomys ordii 88.07 0.00e+00 1321.00
IUUC-Ete-032828 Echinops telfairi 85.77 0.00e+00 802.00
IUUC-Eca-034300 Equus caballus 92.98 0.00e+00 1330.00
IUUC-Eeu-034458 Erinaceus europaeus 89.08 0.00e+00 1285.00
IUUC-Fca-035753 Felis catus 86.93 0.00e+00 1919.00
IUUC-Fal-037062 Ficedula albicollis 67.52 0.00e+00 1427.00
IUUC-Gac-041867 Gasterosteus aculeatus 53.51 0.00e+00 1127.00
IUUC-Ggo-045384 Gorilla gorilla 98.44 0.00e+00 1449.00
IUUC-Hsa-046277 Homo sapiens 98.70 0.00e+00 1454.00
IUUC-Itr-048276 Ictidomys tridecemlineatus 67.77 6.00e-176 610.00
IUUC-Loc-052636 Lepisosteus oculatus 63.31 0.00e+00 1390.00
IUUC-Laf-053808 Loxodonta africana 76.90 0.00e+00 1313.00
IUUC-Meu-056416 Macropus eugenii 71.96 0.00e+00 1014.00
IUUC-Mga-060011 Meleagris gallopavo 62.62 0.00e+00 1320.00
IUUC-Mmr-060720 Microcebus murinus 90.92 0.00e+00 1310.00
IUUC-Mdo-061955 Monodelphis domestica 86.86 0.00e+00 1892.00
IUUC-Mmu-063870 Mus musculus 88.11 0.00e+00 1345.00
IUUC-Mpu-066454 Mustela putorius furo 93.58 0.00e+00 1997.00
IUUC-Mlu-067487 Myotis lucifugus 85.45 0.00e+00 1249.00
IUUC-Nfi-068458 Neosartorya fischeri 33.96 2.00e-10 62.00
IUUC-Nle-070044 Nomascus leucogenys 99.09 0.00e+00 1463.00
IUUC-Opr-070888 Ochotona princeps 98.19 3.00e-162 566.00
IUUC-Ocu-074523 Oryctolagus cuniculus 88.08 0.00e+00 1314.00
IUUC-Ola-086393 Oryzias latipes 51.97 0.00e+00 1095.00
IUUC-Oga-088618 Otolemur garnettii 93.33 0.00e+00 1365.00
IUUC-Oar-089848 Ovis aries 93.14 0.00e+00 2038.00
IUUC-Ptr-091630 Pan troglodytes 98.45 0.00e+00 954.00
IUUC-Pan-092882 Papio anubis 99.77 0.00e+00 1650.00
IUUC-Psi-093422 Pelodiscus sinensis 73.08 0.00e+00 1620.00
IUUC-Pma-094250 Petromyzon marinus 51.88 3.00e-80 291.00
IUUC-Pab-098337 Pongo abelii 98.57 0.00e+00 1453.00
IUUC-Pca-100901 Procavia capensis 70.60 0.00e+00 991.00
IUUC-Pva-102226 Pteropus vampyrus 84.80 0.00e+00 1115.00
IUUC-Rno-105735 Rattus norvegicus 90.66 0.00e+00 2040.00
IUUC-Sha-107489 Sarcophilus harrisii 85.88 0.00e+00 1281.00
IUUC-Ssl-108532 Sclerotinia sclerotiorum 34.57 6.00e-09 57.00
IUUC-Sar-112977 Sorex araneus 74.87 0.00e+00 808.00
IUUC-Ssc-115463 Sus scrofa 91.30 0.00e+00 1113.00
IUUC-Tgu-116609 Taeniopygia guttata 65.60 0.00e+00 928.00
IUUC-Tsy-118971 Tarsius syrichta 96.87 0.00e+00 639.00
IUUC-Ttr-128887 Tursiops truncatus 84.37 0.00e+00 1223.00
IUUC-Vpa-130614 Vicugna pacos 89.92 0.00e+00 886.00
Created Date 25-Jun-2017

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