iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106827

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01194056

Gene Name

FBXO18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000009789.1	ENSSHAT00000011478.1	ENSSHAP00000011382.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/SCF/F-box	67.87	0.00e+00	1451.00	IUUC-Hsa-046650
E3 adaptor/Cullin RING/SCF/F-box	29.82	3.00e-41	165.00	IUUC-Spo-108147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MRRSKRTQLT ALDCLHLAQS REGSFSLTQP LSQRWTSKDL NWRLCPKSKK RNREQGFLRR 60
VTDFFPVSQR SCTSDMAESG STDENNASDD EMAFACALPQ EHERESNLTP LGSVVTSRKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCCGTGAG AGCGGTTTCG TTGCGGGTGC GGGCGGGGTT TGGGGCTGGG GAAAGAGGTG 60
GAGAGAGTAG CCGAGCCCAT CCCTGTTGGG CAGCCTTAGA ACTTGAACAA TGACCGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014017--DNA_helicase_UvrD-like_C
IPR000212--DNA_helicase_UvrD/REP
IPR001810--F-box_dom
IPR027417--P-loop_NTPase

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13361--UvrD_C

Gene Ontology

GO:0000785--C:chromatin
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0043138--F:3'-5' DNA helicase activity
GO:0005524--F:ATP binding
GO:0004003--F:ATP-dependent DNA helicase activity
GO:0015616--F:DNA translocase activity
GO:0003690--F:double-stranded DNA binding
GO:0003697--F:single-stranded DNA binding
GO:0008219--P:cell death
GO:0006974--P:cellular response to DNA damage stimulus
GO:0000737--P:DNA catabolic process, endonucleolytic
GO:0035562--P:negative regulation of chromatin binding
GO:2000042--P:negative regulation of double-strand break repair via homologous recombination
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0001934--P:positive regulation of protein phosphorylation
GO:0016567--P:protein ubiquitination
GO:0031297--P:replication fork processing
GO:0048478--P:replication fork protection
GO:0072429--P:response to intra-S DNA damage checkpoint signaling

KEGG

shr:100932547

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000424	Aegilops tauschii	43.48	1.00e-03	39.30
IUUC-Aml-001396	Ailuropoda melanoleuca	67.87	0.00e+00	1430.00
IUUC-Atr-002826	Amborella trichopoda	40.32	7.00e-03	36.60
IUUC-Apl-003317	Anas platyrhynchos	46.93	0.00e+00	900.00
IUUC-Aca-004498	Anolis carolinensis	51.64	0.00e+00	925.00
IUUC-Ani-009226	Aspergillus nidulans	35.87	2.00e-05	45.10
IUUC-Ate-010526	Aspergillus terreus	40.58	2.00e-04	42.00
IUUC-Ame-011808	Astyanax mexicanus	56.75	1.00e-130	459.00
IUUC-Bta-013250	Bos taurus	67.21	0.00e+00	1415.00
IUUC-Cja-019638	Callithrix jacchus	67.87	0.00e+00	1451.00
IUUC-Cfa-020195	Canis familiaris	69.96	0.00e+00	1412.00
IUUC-Cpo-022269	Cavia porcellus	65.11	0.00e+00	1365.00
IUUC-Cre-022611	Chlamydomonas reinhardtii	32.63	5.00e-08	53.90
IUUC-Csa-024060	Chlorocebus sabaeus	69.65	0.00e+00	1335.00
IUUC-Cho-025003	Choloepus hoffmanni	71.97	7.00e-171	594.00
IUUC-Cin-025694	Ciona intestinalis	28.36	8.00e-32	131.00
IUUC-Dre-028083	Danio rerio	43.37	0.00e+00	852.00
IUUC-Dno-029203	Dasypus novemcinctus	65.33	0.00e+00	1318.00
IUUC-Dor-030477	Dipodomys ordii	76.73	0.00e+00	654.00
IUUC-Ete-032861	Echinops telfairi	67.59	0.00e+00	1422.00
IUUC-Eca-033205	Equus caballus	68.54	0.00e+00	1478.00
IUUC-Eeu-034784	Erinaceus europaeus	70.88	0.00e+00	1035.00
IUUC-Fca-035797	Felis catus	67.27	0.00e+00	1425.00
IUUC-Gmo-038855	Gadus morhua	45.31	1.00e-121	430.00
IUUC-Gga-040326	Gallus gallus	49.32	0.00e+00	943.00
IUUC-Gac-042240	Gasterosteus aculeatus	40.90	0.00e+00	714.00
IUUC-Ggo-045050	Gorilla gorilla	65.34	0.00e+00	1336.00
IUUC-Hsa-046650	Homo sapiens	67.78	0.00e+00	1419.00
IUUC-Itr-047965	Ictidomys tridecemlineatus	77.26	0.00e+00	645.00
IUUC-Lch-050231	Latimeria chalumnae	41.98	6.00e-160	557.00
IUUC-Loc-051884	Lepisosteus oculatus	48.16	0.00e+00	977.00
IUUC-Lma-053267	Leptosphaeria maculans	23.88	7.00e-04	40.00
IUUC-Laf-053843	Loxodonta africana	67.97	0.00e+00	1440.00
IUUC-Mcc-055570	Macaca mulatta	68.06	0.00e+00	1436.00
IUUC-Meu-056798	Macropus eugenii	78.54	0.00e+00	635.00
IUUC-Mtr-057915	Medicago truncatula	37.68	3.00e-04	41.60
IUUC-Mga-059648	Meleagris gallopavo	48.91	0.00e+00	900.00
IUUC-Mmr-060757	Microcebus murinus	65.94	0.00e+00	1371.00
IUUC-Mdo-061913	Monodelphis domestica	88.37	0.00e+00	1799.00
IUUC-Mmu-064337	Mus musculus	66.06	0.00e+00	1419.00
IUUC-Mpu-066483	Mustela putorius furo	66.73	0.00e+00	1434.00
IUUC-Mlu-068204	Myotis lucifugus	64.86	0.00e+00	1371.00
IUUC-Ncr-068735	Neurospora crassa	30.34	1.00e-04	42.40
IUUC-Nle-070053	Nomascus leucogenys	68.06	0.00e+00	1396.00
IUUC-Opr-070588	Ochotona princeps	63.49	0.00e+00	1340.00
IUUC-Ont-072655	Oreochromis niloticus	45.10	0.00e+00	723.00
IUUC-Oan-073351	Ornithorhynchus anatinus	59.73	0.00e+00	1238.00
IUUC-Ocu-074465	Oryctolagus cuniculus	66.92	0.00e+00	1380.00
IUUC-Oin-079176	Oryza indica	23.62	3.00e-05	43.10
IUUC-Opu-083155	Oryza punctata	47.50	2.00e-03	37.70
IUUC-Olu-087831	Ostreococcus lucimarinus	32.42	6.00e-63	236.00
IUUC-Oga-089088	Otolemur garnettii	65.97	0.00e+00	1386.00
IUUC-Oar-089870	Ovis aries	66.35	0.00e+00	1396.00
IUUC-Ptr-090957	Pan troglodytes	67.92	0.00e+00	1402.00
IUUC-Pan-092632	Papio anubis	68.06	0.00e+00	1395.00
IUUC-Psi-093035	Pelodiscus sinensis	51.90	0.00e+00	1056.00
IUUC-Pno-094870	Phaeosphaeria nodorum	30.95	1.50e-02	35.40
IUUC-Ppa-095660	Physcomitrella patens	36.99	2.00e-03	38.50
IUUC-Pfo-096902	Poecilia formosa	43.42	0.00e+00	661.00
IUUC-Pab-098206	Pongo abelii	67.47	0.00e+00	1311.00
IUUC-Pop-098801	Populus trichocarpa	37.14	5.00e-04	40.00
IUUC-Pca-100238	Procavia capensis	63.97	0.00e+00	1343.00
IUUC-Pva-103182	Pteropus vampyrus	66.70	0.00e+00	1400.00
IUUC-Pte-104033	Pyrenophora teres	35.71	6.00e-03	36.60
IUUC-Pyt-104599	Pyrenophora triticirepentis	37.31	5.00e-03	36.60
IUUC-Rno-105141	Rattus norvegicus	66.44	0.00e+00	1418.00
IUUC-Sce-106341	Saccharomyces cerevisiae	33.33	8.20e-02	32.30
IUUC-Sja-107882	Schizosaccharomyces japonicus	31.20	2.00e-44	174.00
IUUC-Spo-108147	Schizosaccharomyces pombe	29.82	7.00e-42	165.00
IUUC-Ssl-108584	Sclerotinia sclerotiorum	23.36	1.00e-03	38.90
IUUC-Sly-111170	Solanum lycopersicum	37.88	4.10e-02	33.10
IUUC-Sre-115025	Sporisorium reilianum	32.28	5.00e-38	153.00
IUUC-Ssc-116188	Sus scrofa	73.34	0.00e+00	1018.00
IUUC-Tgu-116612	Taeniopygia guttata	53.91	6.00e-153	533.00
IUUC-Tsy-119560	Tarsius syrichta	66.94	2.00e-95	343.00
IUUC-Tni-120734	Tetraodon nigroviridis	45.35	0.00e+00	687.00
IUUC-Tre-122089	Trichoderma reesei	32.84	3.00e-03	37.40
IUUC-Tme-127009	Tuber melanosporum	35.62	5.00e-04	40.40
IUUC-Tbe-127431	Tupaia belangeri	66.23	0.00e+00	1200.00
IUUC-Ttr-128744	Tursiops truncatus	64.61	0.00e+00	1354.00
IUUC-Uma-129536	Ustilago maydis	34.48	7.00e-39	156.00
IUUC-Vpa-130123	Vicugna pacos	47.27	2.00e-51	196.00
IUUC-Xtr-132902	Xenopus tropicalis	54.91	0.00e+00	957.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence