iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005347

UUCD1 version

UUC-AnC-00999

Ensembl Protein ID

ENSACAP00000001504.3

UniProt Accession

H9G5A9; H9G5A9_ANOCA

Protein Name

Ubiquitinyl hydrolase 1

Gene Name

usp22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000001485.3	ENSACAT00000001540.3	ENSACAP00000001504.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.90e-93	311.9	177	535

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ +++k++ +   +p+ +l++++ +lf+e+++++++   p +ll+ +++ a+++ gyeqq
   Q: 177  GLINLGNTCFMNCIVQALTHTPLLRDFFLS-DRHKCEMQ---SPSSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQ 261
           9*****************************.99999975...78********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl   ld l++++k                  ++ ++ +++++ +++i+++F g l+s+++c+ c+ vs++ +pf+d+sl++pg+
   Q: 262  DAHEFLIAALDVLHRHCKG----------------DDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCHGVSTTIDPFWDISLDLPGS 334
           *****************22................22335677899999**************************************** PP
   S: 180  eetkke....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
           ++   +                    +l+dcL+ ft++e+l ++ k++c+ c+++qe++k+l++kklP v ++hLkRf  +++ k r+k
   Q: 335  STPFWPlspgsdgsvvngeshvtgttTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRF--EHSAKLRRK 421
           *877779***********************************************************************..5666899** PP
   S: 249  inkkvefpleLdlspfctspeekqke...........................kkkYeLiavvvHsGslssGHYvayvknekgkWllfd 310
           i+++v+fpleLd++pf++s++e +++                           ++kY+L+avv+H+G+l+sGHY+++++++k++W+++d
   Q: 422  ITTYVSFPLELDMTPFMASRSERSAKtkknlpsfgkesrmngqyqqpadslnnDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCD 510
           *******************5555544566666666666666666666777777************************************ PP
   S: 311  DskVtevkeeevleetgstaYvlfYkrr 338
           D  +t+ + ++vl    s++Y+lfY+++
   Q: 511  DAIITKASIKDVLD---SEGYLLFYHKQ 535
           **************...********985 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSPPAAGCCH VTGFKVENWK QNLRVIYQCF VWSGSAEARK RKAKSCICHM CGAHLNRLHS 60
CLYCVFFGCF TKKHIHEHAK AKRHNLAIDL LYGGIYCFMC QDYIYDKDME QIAKEEQRKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTCCGC CGGCCGCCGG GTGCTGCCAT GTGACCGGCT TCAAGGTGGA GAACTGGAAG 60
CAGAACCTGC GCGTCATCTA CCAGTGCTTC GTCTGGAGCG GGTCCGCCGA GGCCAGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0000124--C:SAGA complex
GO:0010485--F:H4 histone acetyltransferase activity
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016578--P:histone deubiquitination
GO:0016574--P:histone ubiquitination
GO:0045931--P:positive regulation of mitotic cell cycle
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000393	Aegilops tauschii	37.20	6.00e-64	238.00
IUUC-Aml-001343	Ailuropoda melanoleuca	87.41	0.00e+00	993.00
IUUC-Atr-002653	Amborella trichopoda	36.98	4.00e-98	351.00
IUUC-Apl-003433	Anas platyrhynchos	95.79	0.00e+00	1000.00
IUUC-Aly-006565	Arabidopsis lyrata	35.74	6.00e-70	258.00
IUUC-Ath-007536	Arabidopsis thaliana	35.74	8.00e-70	257.00
IUUC-Ago-007811	Ashbya gossypii	28.82	8.00e-50	191.00
IUUC-Acl-008124	Aspergillus clavatus	30.25	8.00e-56	211.00
IUUC-Afl-008464	Aspergillus flavus	31.01	2.00e-52	199.00
IUUC-Afu-008912	Aspergillus fumigatus	29.57	4.00e-53	202.00
IUUC-Ani-009168	Aspergillus nidulans	30.00	3.00e-54	205.00
IUUC-Ang-009694	Aspergillus niger	29.44	1.00e-53	203.00
IUUC-Aor-010035	Aspergillus oryzae	32.98	8.00e-37	146.00
IUUC-Ate-010382	Aspergillus terreus	30.34	4.00e-50	191.00
IUUC-Ame-011253	Astyanax mexicanus	82.63	0.00e+00	833.00
IUUC-Bgr-012150	Blumeria graminis	30.15	9.00e-47	181.00
IUUC-Bta-013303	Bos taurus	88.15	0.00e+00	999.00
IUUC-Bci-013604	Botrytis cinerea	31.56	1.00e-55	210.00
IUUC-Bdi-014171	Brachypodium distachyon	34.70	4.00e-76	278.00
IUUC-Bol-016509	Brassica oleracea	36.46	6.00e-72	265.00
IUUC-Bra-016962	Brassica rapa	35.07	5.00e-70	258.00
IUUC-Cja-019283	Callithrix jacchus	89.65	0.00e+00	849.00
IUUC-Cfa-021239	Canis familiaris	89.22	0.00e+00	938.00
IUUC-Cpo-022354	Cavia porcellus	88.52	0.00e+00	999.00
IUUC-Csa-023145	Chlorocebus sabaeus	88.89	0.00e+00	1006.00
IUUC-Cho-024938	Choloepus hoffmanni	80.15	6.00e-61	228.00
IUUC-Cin-025109	Ciona intestinalis	55.41	2.00e-121	428.00
IUUC-Csv-026214	Ciona savignyi	53.42	5.00e-173	600.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	30.12	2.00e-52	199.00
IUUC-Cne-027085	Cryptococcus neoformans	31.93	3.00e-62	233.00
IUUC-Dre-027433	Danio rerio	90.16	0.00e+00	923.00
IUUC-Dno-030095	Dasypus novemcinctus	89.58	0.00e+00	939.00
IUUC-Dor-030481	Dipodomys ordii	84.04	7.00e-94	337.00
IUUC-Dse-031415	Dothistroma septosporum	29.93	1.00e-59	224.00
IUUC-Dme-032074	Drosophila melanogaster	49.73	1.00e-135	476.00
IUUC-Ete-033175	Echinops telfairi	70.17	0.00e+00	665.00
IUUC-Eca-033736	Equus caballus	88.98	0.00e+00	931.00
IUUC-Eeu-034814	Erinaceus europaeus	91.11	1.00e-118	419.00
IUUC-Fca-035861	Felis catus	89.58	0.00e+00	937.00
IUUC-Fal-037645	Ficedula albicollis	95.93	0.00e+00	984.00
IUUC-Fox-038046	Fusarium oxysporum	30.33	5.00e-53	201.00
IUUC-Fso-038321	Fusarium solani	30.98	2.00e-52	199.00
IUUC-Gmo-038474	Gadus morhua	90.03	4.00e-169	587.00
IUUC-Ggr-040044	Gaeumannomyces graminis	30.80	1.00e-53	204.00
IUUC-Gga-040624	Gallus gallus	95.93	0.00e+00	1087.00
IUUC-Gac-042197	Gasterosteus aculeatus	84.84	0.00e+00	936.00
IUUC-Gma-042897	Glycine max	32.72	2.00e-81	296.00
IUUC-Ggo-044409	Gorilla gorilla	89.07	0.00e+00	1010.00
IUUC-Hsa-046521	Homo sapiens	89.07	0.00e+00	1008.00
IUUC-Hvu-047739	Hordeum vulgare	38.01	2.00e-68	252.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	88.15	0.00e+00	999.00
IUUC-Kpa-049135	Komagataella pastoris	33.67	6.00e-66	244.00
IUUC-Lch-050537	Latimeria chalumnae	90.93	0.00e+00	1018.00
IUUC-Lpe-050969	Leersia perrieri	37.32	4.00e-73	268.00
IUUC-Loc-052765	Lepisosteus oculatus	83.27	0.00e+00	914.00
IUUC-Lma-053105	Leptosphaeria maculans	33.27	4.00e-65	242.00
IUUC-Laf-053571	Loxodonta africana	89.98	0.00e+00	939.00
IUUC-Mcc-055166	Macaca mulatta	88.89	0.00e+00	1006.00
IUUC-Mor-057103	Magnaporthe oryzae	30.43	1.00e-54	206.00
IUUC-Mpo-057621	Magnaporthe poae	31.21	1.00e-53	203.00
IUUC-Mtr-057894	Medicago truncatula	36.51	5.00e-84	305.00
IUUC-Mla-059185	Melampsora laricipopulina	32.09	4.00e-40	159.00
IUUC-Mga-059709	Meleagris gallopavo	95.79	0.00e+00	1000.00
IUUC-Mvi-060530	Microbotryum violaceum	33.33	8.00e-57	214.00
IUUC-Mmr-060988	Microcebus murinus	88.70	0.00e+00	1007.00
IUUC-Mdo-063065	Monodelphis domestica	92.04	0.00e+00	1026.00
IUUC-Mmu-063829	Mus musculus	88.15	0.00e+00	1003.00
IUUC-Mac-065419	Musa acuminata	38.32	4.00e-70	258.00
IUUC-Mpu-066687	Mustela putorius furo	88.15	0.00e+00	994.00
IUUC-Mlu-067330	Myotis lucifugus	78.56	0.00e+00	879.00
IUUC-Nfi-068423	Neosartorya fischeri	29.57	5.00e-53	201.00
IUUC-Ncr-068809	Neurospora crassa	28.49	2.00e-53	202.00
IUUC-Nle-069261	Nomascus leucogenys	85.00	0.00e+00	952.00
IUUC-Opr-070469	Ochotona princeps	73.29	0.00e+00	662.00
IUUC-Ont-071961	Oreochromis niloticus	87.59	0.00e+00	969.00
IUUC-Oan-073565	Ornithorhynchus anatinus	89.02	0.00e+00	969.00
IUUC-Ocu-074435	Oryctolagus cuniculus	88.43	0.00e+00	975.00
IUUC-Oba-075688	Oryza barthii	35.05	4.00e-75	275.00
IUUC-Obr-076652	Oryza brachyantha	40.46	5.00e-74	271.00
IUUC-Ogl-077910	Oryza glaberrima	35.45	1.00e-79	290.00
IUUC-Ogu-078479	Oryza glumaepatula	35.45	1.00e-79	290.00
IUUC-Oin-079697	Oryza indica	39.28	3.00e-75	275.00
IUUC-Olo-080811	Oryza longistaminata	40.13	1.00e-52	199.00
IUUC-Ome-081706	Oryza meridionalis	35.25	6.00e-79	288.00
IUUC-Oni-083070	Oryza nivara	35.45	3.00e-79	289.00
IUUC-Opu-083605	Oryza punctata	38.93	6.00e-67	247.00
IUUC-Oru-084522	Oryza rufipogon	35.45	1.00e-79	290.00
IUUC-Osa-085351	Oryza sativa	39.23	5.00e-76	278.00
IUUC-Ola-086743	Oryzias latipes	82.87	0.00e+00	741.00
IUUC-Olu-087695	Ostreococcus lucimarinus	30.39	7.00e-49	187.00
IUUC-Oga-089131	Otolemur garnettii	88.72	0.00e+00	1007.00
IUUC-Oar-089319	Ovis aries	89.16	0.00e+00	930.00
IUUC-Ptr-090783	Pan troglodytes	89.98	0.00e+00	942.00
IUUC-Pan-092927	Papio anubis	88.70	0.00e+00	1004.00
IUUC-Psi-093670	Pelodiscus sinensis	95.98	0.00e+00	1000.00
IUUC-Pma-094323	Petromyzon marinus	65.43	0.00e+00	697.00
IUUC-Pno-095141	Phaeosphaeria nodorum	28.84	3.00e-52	199.00
IUUC-Ppa-095413	Physcomitrella patens	34.82	5.00e-86	311.00
IUUC-Pfo-096462	Poecilia formosa	87.03	0.00e+00	986.00
IUUC-Pab-097612	Pongo abelii	88.89	0.00e+00	1007.00
IUUC-Pop-099558	Populus trichocarpa	34.75	6.00e-87	314.00
IUUC-Pca-100329	Procavia capensis	78.19	0.00e+00	875.00
IUUC-Ppe-102020	Prunus persica	35.92	1.00e-92	333.00
IUUC-Pva-102721	Pteropus vampyrus	74.49	0.00e+00	818.00
IUUC-Pgr-103657	Puccinia graminis	29.86	1.00e-37	151.00
IUUC-Pte-104340	Pyrenophora teres	32.07	7.00e-58	218.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	34.56	9.00e-65	241.00
IUUC-Rno-105247	Rattus norvegicus	88.33	0.00e+00	1003.00
IUUC-Sce-106247	Saccharomyces cerevisiae	30.08	6.00e-50	191.00
IUUC-Sha-107538	Sarcophilus harrisii	89.66	1.00e-121	428.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	32.10	1.00e-63	236.00
IUUC-Spo-108226	Schizosaccharomyces pombe	30.64	3.00e-58	219.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	30.43	1.00e-51	197.00
IUUC-Smo-109310	Selaginella moellendorffii	34.82	6.00e-87	314.00
IUUC-Sit-109716	Setaria italica	34.91	6.00e-79	288.00
IUUC-Sly-111077	Solanum lycopersicum	35.77	3.00e-78	286.00
IUUC-Stu-112203	Solanum tuberosum	37.17	3.00e-71	262.00
IUUC-Sar-113174	Sorex araneus	76.20	0.00e+00	796.00
IUUC-Sbi-114205	Sorghum bicolor	34.58	4.00e-80	291.00
IUUC-Sre-115195	Sporisorium reilianum	32.95	8.00e-31	128.00
IUUC-Ssc-115315	Sus scrofa	79.85	0.00e+00	901.00
IUUC-Tgu-116938	Taeniopygia guttata	92.99	0.00e+00	959.00
IUUC-Tru-117622	Takifugu rubripes	89.07	0.00e+00	1003.00
IUUC-Tsy-119431	Tarsius syrichta	78.51	0.00e+00	787.00
IUUC-Tni-120661	Tetraodon nigroviridis	88.52	0.00e+00	991.00
IUUC-Tca-121716	Theobroma cacao	33.50	2.00e-84	306.00
IUUC-Tre-122139	Trichoderma reesei	30.62	3.00e-52	199.00
IUUC-Tvi-122599	Trichoderma virens	29.92	1.00e-52	200.00
IUUC-Tae-125608	Triticum aestivum	35.32	3.00e-86	312.00
IUUC-Tme-127115	Tuber melanosporum	35.37	1.00e-78	286.00
IUUC-Ttr-129006	Tursiops truncatus	78.72	0.00e+00	865.00
IUUC-Uma-129455	Ustilago maydis	31.02	2.00e-33	137.00
IUUC-Vda-129829	Verticillium dahliae	31.27	7.00e-34	137.00
IUUC-Vvi-131477	Vitis vinifera	34.99	5.00e-77	281.00
IUUC-Xtr-132444	Xenopus tropicalis	92.41	0.00e+00	1045.00
IUUC-Xma-133514	Xiphophorus maculatus	89.44	0.00e+00	1001.00
IUUC-Yli-134357	Yarrowia lipolytica	29.93	4.00e-46	179.00
IUUC-Zma-134945	Zea mays	34.72	5.00e-77	281.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence