iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040332

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000033

Gene Name

HECTD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000010217.5	ENSGALT00000016610.4	ENSGALP00000016591.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	9.70e-76	255.7	512	837

Active Site

Position(s)	Description	Evidence
807	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 9    levefvgEegldlgGvtreflallskelqnpd......lglflysendketlqpnpdsglknp..ehlklFeflGrllgkalqdgrlld 89
           +e++f  E  +d+gG +r+ la +s+el+ ++      l++f++++n+ +++  ++d+++ np  + +  +e++G+++g al+ +++l 
   Q: 512  WECKFIAEGIIDQGGGFRDSLADMSEELCPSSadtpvpLPFFVRTSNQGNSTGEARDMYVPNPscKDFPKYEWIGQIMGAALRGKEFLV 600
           45*****************************9999*99**********************9998889999******************* PP
   S: 90   lplsksfyklllgkklsl.edleevdpelykslkeikenaesdieelgldltfs...vseeilgetkeeeLkpgGenipVtneNkeeYv 174
           l l+ +++k+l g+++s+ +d+++vd+ l+k l+ ++ +     +  +++++f    + +++l++++ +eL+p+G+n+ V +e+++e++
   Q: 601  LALPGFVWKQLTGEEVSWsKDFAAVDSVLVKLLEVMEVM-----DRDTFEFKFGnelTYTTVLSDQRMVELIPNGSNTVVHYEDRKEFI 684
           *************************************77.....333355555533445567999************************ PP
   S: 175  klvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerka 263
           +lv ++rl+e  keq+ a+++G+ +v+p+ +l+l+t++ele  +cG++e++v++lkk t++++ +++ +  +q+Fwe+l++f++e+r++
   Q: 685  RLVQKARLEE-SKEQIMAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALKKLTRFED-FEPLDTRVQYFWEALNNFTNEDRSR 771
           *********9.9*************************************************76.************************* PP
   S: 264  fLqFvTgssrlPlgGfaelkprlfvirk...dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           fL+FvTg+srlP+        r++++++   ++++d lP+s+TC ++L LP+Y + ++++ekL+yA  ++ +++
   Q: 772  FLRFVTGRSRLPA--------RIYIYPDklgSETTDALPESSTCSSTLFLPNYATAKVCEEKLRYAAYNCVAID 837
           ************5........66777777989999*********************************998776 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MRAGGEAPHQ VLGRLRFLLQ CSECFRRARP LPAALCYVPR EVQYKICKDP SAAASSRSLL 60
SVWDSPGPAR GSKRAARATI EVRKGGCLRA TGEEYCNSAG LWVKLSKEQL EEYKSGCDLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCGGGCGG GCGGAGAGGC TCCGCACCAG GTGCTGGGCC GGCTGCGGTT CCTGCTGCAG 60
TGCAGCGAGT GCTTCCGCCG CGCCCGGCCG CTGCCCGCCG CGCTGTGCTA CGTGCCCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR004939--APC_su10/DOC_dom
IPR008979--Galactose-bd-like
IPR000569--HECT_dom

PROSITE

PS51284--DOC
PS50237--HECT

Pfam

PF03256--ANAPC10
PF00632--HECT

SMART

SM01337--APC10
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

gga:424589

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001229	Ailuropoda melanoleuca	80.14	0.00e+00	1402.00
IUUC-Apl-003715	Anas platyrhynchos	98.38	0.00e+00	1486.00
IUUC-Aca-004377	Anolis carolinensis	86.97	0.00e+00	1518.00
IUUC-Ame-011918	Astyanax mexicanus	68.30	0.00e+00	1199.00
IUUC-Bta-012736	Bos taurus	80.49	0.00e+00	1419.00
IUUC-Cja-019926	Callithrix jacchus	80.26	0.00e+00	1415.00
IUUC-Cfa-020753	Canis familiaris	87.69	0.00e+00	1067.00
IUUC-Cpo-021415	Cavia porcellus	79.91	0.00e+00	1407.00
IUUC-Csa-023096	Chlorocebus sabaeus	80.07	0.00e+00	1410.00
IUUC-Dre-028746	Danio rerio	75.03	0.00e+00	1281.00
IUUC-Dno-029293	Dasypus novemcinctus	87.57	0.00e+00	984.00
IUUC-Dor-031113	Dipodomys ordii	88.16	0.00e+00	1134.00
IUUC-Ete-032601	Echinops telfairi	76.00	0.00e+00	1235.00
IUUC-Eca-034198	Equus caballus	79.02	0.00e+00	1404.00
IUUC-Eeu-034708	Erinaceus europaeus	87.72	0.00e+00	831.00
IUUC-Fca-035478	Felis catus	81.18	0.00e+00	1409.00
IUUC-Fal-037366	Ficedula albicollis	93.20	0.00e+00	1575.00
IUUC-Gmo-039020	Gadus morhua	78.47	0.00e+00	1070.00
IUUC-Gac-042336	Gasterosteus aculeatus	74.56	0.00e+00	1325.00
IUUC-Ggo-045382	Gorilla gorilla	80.19	0.00e+00	1410.00
IUUC-Hsa-046562	Homo sapiens	80.19	0.00e+00	1410.00
IUUC-Itr-048208	Ictidomys tridecemlineatus	80.14	0.00e+00	1412.00
IUUC-Lch-049606	Latimeria chalumnae	71.14	0.00e+00	890.00
IUUC-Loc-052448	Lepisosteus oculatus	67.56	0.00e+00	1164.00
IUUC-Laf-054507	Loxodonta africana	79.63	0.00e+00	1420.00
IUUC-Mcc-055690	Macaca mulatta	79.95	0.00e+00	1408.00
IUUC-Meu-055970	Macropus eugenii	80.80	0.00e+00	1391.00
IUUC-Mga-059654	Meleagris gallopavo	99.59	0.00e+00	1479.00
IUUC-Mmr-061069	Microcebus murinus	80.14	0.00e+00	1412.00
IUUC-Mdo-062547	Monodelphis domestica	89.60	0.00e+00	773.00
IUUC-Mmu-063096	Mus musculus	80.14	0.00e+00	1420.00
IUUC-Mpu-065846	Mustela putorius furo	80.26	0.00e+00	1414.00
IUUC-Mlu-067992	Myotis lucifugus	80.89	0.00e+00	1364.00
IUUC-Nle-069565	Nomascus leucogenys	79.30	0.00e+00	1311.00
IUUC-Opr-070853	Ochotona princeps	74.21	0.00e+00	915.00
IUUC-Ont-071628	Oreochromis niloticus	75.23	0.00e+00	1311.00
IUUC-Ocu-074094	Oryctolagus cuniculus	80.02	0.00e+00	1411.00
IUUC-Ola-087384	Oryzias latipes	73.92	0.00e+00	1331.00
IUUC-Oga-088224	Otolemur garnettii	79.91	0.00e+00	1415.00
IUUC-Oar-090043	Ovis aries	78.65	0.00e+00	1347.00
IUUC-Ptr-090852	Pan troglodytes	79.95	0.00e+00	1401.00
IUUC-Pan-092787	Papio anubis	79.95	0.00e+00	1409.00
IUUC-Psi-092986	Pelodiscus sinensis	78.23	0.00e+00	1043.00
IUUC-Pma-094416	Petromyzon marinus	41.41	5.00e-180	624.00
IUUC-Pfo-096720	Poecilia formosa	74.80	0.00e+00	1341.00
IUUC-Pab-098325	Pongo abelii	77.41	0.00e+00	1060.00
IUUC-Pca-100885	Procavia capensis	72.93	0.00e+00	1072.00
IUUC-Pva-102829	Pteropus vampyrus	66.71	0.00e+00	1110.00
IUUC-Rno-104882	Rattus norvegicus	80.49	0.00e+00	1417.00
IUUC-Sha-106811	Sarcophilus harrisii	84.43	2.00e-109	389.00
IUUC-Sar-113020	Sorex araneus	75.30	0.00e+00	652.00
IUUC-Ssc-115436	Sus scrofa	84.07	2.00e-138	484.00
IUUC-Tgu-117042	Taeniopygia guttata	97.03	0.00e+00	1632.00
IUUC-Tru-118419	Takifugu rubripes	72.79	0.00e+00	1247.00
IUUC-Tsy-118829	Tarsius syrichta	80.41	0.00e+00	847.00
IUUC-Tni-120410	Tetraodon nigroviridis	61.72	0.00e+00	1010.00
IUUC-Tbe-128113	Tupaia belangeri	87.99	0.00e+00	711.00
IUUC-Ttr-128167	Tursiops truncatus	76.29	0.00e+00	1323.00
IUUC-Xtr-132910	Xenopus tropicalis	71.06	0.00e+00	1172.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence