iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004257

UUCD1 version

UUC-AnC-00239

Ensembl Protein ID

ENSACAP00000010376.3

UniProt Accession

H9GGJ4; H9GGJ4_ANOCA

Protein Name

Uncharacterized protein

Gene Name

WDSUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000010555.3	ENSACAT00000010590.3	ENSACAP00000010376.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.30e-23	82.8	415	486
E3 adaptor/Cullin RING/DCX/DWD	3.00e-39	131.2	11	40
UBD/Beta-Prp	7.10e-53	179.7	3	190

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+eflCpI+ elM++Pv++++G++y+++++e w+ ++++++P+t+ +l++  l+Pn tl+  i++w+e + 
   Q: 415  IPDEFLCPITRELMKEPVIAADGYSYEKEAMESWIVKQRHSSPMTNLHLQSLVLTPNRTLKMAIDRWLENHP 486
           8*******************************************************************9985 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlr 31
           H+d+v+c+afs+ +l+++s D+t+++++l+
   Q: 11   HKDDVNCCAFSSSFLATCSLDKTVRLYSLS 40
           **********448**************986 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcv..htlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           kl+ +l +h++ v+++ fs++  +l+t+s D+t+++++ls+++ +  + l+gh++ v ++ fsp g++l+s s d    +w++++g +l
   Q: 3    KLICTLVDHKDDVNCCAFSSS--FLATCSLDKTVRLYSLSNFEELpySPLEGHTYAVHCCCFSPLGHVLASCSTDGNTVLWNTHNGLKL 89
           6788999**************..9****************99865226789************************************** PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
             ++ + +  v++ +++pd+  lvsG++D+ v+lW++++ k+ r  +  +++s    +f++ng ++v+gs  g+++lwd +  +c++  
   Q: 90   AVLEHPCRNPVRICRFSPDSTFLVSGAADGSVNLWNVQSLKVYRSGSV-KDGSLVACAFSPNGSFFVTGSSCGDLTLWDNKM-RCLYNE 176
           988999999****************************99999999987.999999999*********************965.59**** PP
   S: 219  nghtdnvksvrfsp 232
           ++h+  v++ +fs+
   Q: 177  KAHDLGVTCCDFSS 190
           *********99985 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MVKLICTLVD HKDDVNCCAF SSSFLATCSL DKTVRLYSLS NFEELPYSPL EGHTYAVHCC 60
CFSPLGHVLA SCSTDGNTVL WNTHNGLKLA VLEHPCRNPV RICRFSPDST FLVSGAADGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACCTTTAT ATGACCAAAT GGTGAAATTG ATTTGTACTC TAGTAGATCA TAAAGATGAT 60
GTCAACTGCT GTGCCTTCTC CTCTTCCTTC TTGGCTACAT GTTCCTTGGA CAAAACTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	70.84	0.00e+00	704.00
IUUC-Apl-003529	Anas platyrhynchos	72.07	0.00e+00	724.00
IUUC-Ame-011357	Astyanax mexicanus	49.90	5.00e-112	397.00
IUUC-Bta-013032	Bos taurus	69.26	0.00e+00	697.00
IUUC-Cja-018743	Callithrix jacchus	70.43	0.00e+00	698.00
IUUC-Cfa-021197	Canis familiaris	70.23	0.00e+00	706.00
IUUC-Cpo-022279	Cavia porcellus	69.82	0.00e+00	701.00
IUUC-Csa-023954	Chlorocebus sabaeus	70.64	0.00e+00	706.00
IUUC-Cho-025083	Choloepus hoffmanni	57.84	9.00e-123	432.00
IUUC-Cin-025786	Ciona intestinalis	35.63	6.00e-84	304.00
IUUC-Dre-028087	Danio rerio	53.92	7.00e-141	493.00
IUUC-Dno-028919	Dasypus novemcinctus	71.87	0.00e+00	724.00
IUUC-Dor-031112	Dipodomys ordii	69.82	0.00e+00	694.00
IUUC-Ete-032405	Echinops telfairi	67.42	2.00e-139	488.00
IUUC-Eca-033254	Equus caballus	69.40	0.00e+00	710.00
IUUC-Eeu-034545	Erinaceus europaeus	68.58	0.00e+00	673.00
IUUC-Fca-035482	Felis catus	71.05	0.00e+00	709.00
IUUC-Fal-036976	Ficedula albicollis	58.75	8.00e-154	536.00
IUUC-Gmo-039213	Gadus morhua	53.59	4.00e-136	477.00
IUUC-Gga-040561	Gallus gallus	68.64	0.00e+00	687.00
IUUC-Gac-041471	Gasterosteus aculeatus	56.26	4.00e-138	484.00
IUUC-Ggo-045503	Gorilla gorilla	70.43	0.00e+00	703.00
IUUC-Hsa-045910	Homo sapiens	70.64	0.00e+00	704.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	69.07	5.00e-157	546.00
IUUC-Loc-052307	Lepisosteus oculatus	57.56	3.00e-164	571.00
IUUC-Laf-053587	Loxodonta africana	70.64	0.00e+00	705.00
IUUC-Mcc-055679	Macaca mulatta	70.43	0.00e+00	702.00
IUUC-Meu-055962	Macropus eugenii	62.83	3.00e-164	571.00
IUUC-Mga-059652	Meleagris gallopavo	68.65	0.00e+00	689.00
IUUC-Mmr-060943	Microcebus murinus	69.53	0.00e+00	684.00
IUUC-Mdo-062592	Monodelphis domestica	70.61	0.00e+00	706.00
IUUC-Mmu-063577	Mus musculus	68.44	0.00e+00	671.00
IUUC-Mpu-066422	Mustela putorius furo	71.25	0.00e+00	708.00
IUUC-Mlu-067250	Myotis lucifugus	68.17	0.00e+00	686.00
IUUC-Nle-069517	Nomascus leucogenys	70.43	0.00e+00	705.00
IUUC-Opr-070776	Ochotona princeps	71.46	0.00e+00	708.00
IUUC-Ont-071821	Oreochromis niloticus	56.44	5.00e-149	520.00
IUUC-Oan-073706	Ornithorhynchus anatinus	70.31	0.00e+00	703.00
IUUC-Ocu-074766	Oryctolagus cuniculus	64.97	0.00e+00	632.00
IUUC-Ola-086531	Oryzias latipes	54.32	3.00e-142	498.00
IUUC-Oga-088388	Otolemur garnettii	69.40	0.00e+00	697.00
IUUC-Oar-089748	Ovis aries	70.49	0.00e+00	706.00
IUUC-Ptr-090616	Pan troglodytes	70.04	0.00e+00	695.00
IUUC-Pan-091769	Papio anubis	68.93	4.00e-141	494.00
IUUC-Psi-093334	Pelodiscus sinensis	75.31	0.00e+00	707.00
IUUC-Pma-094383	Petromyzon marinus	46.45	2.00e-125	442.00
IUUC-Pfo-096832	Poecilia formosa	49.39	9.00e-130	456.00
IUUC-Pab-098139	Pongo abelii	68.42	1.00e-160	558.00
IUUC-Pca-100523	Procavia capensis	69.33	3.00e-131	461.00
IUUC-Pva-102286	Pteropus vampyrus	69.61	0.00e+00	673.00
IUUC-Rno-104831	Rattus norvegicus	67.97	0.00e+00	673.00
IUUC-Sha-107499	Sarcophilus harrisii	71.46	0.00e+00	715.00
IUUC-Sar-113389	Sorex araneus	68.38	0.00e+00	678.00
IUUC-Tgu-116769	Taeniopygia guttata	69.40	0.00e+00	694.00
IUUC-Tru-118774	Takifugu rubripes	52.61	6.00e-136	477.00
IUUC-Tsy-119595	Tarsius syrichta	59.62	1.00e-132	465.00
IUUC-Tni-119850	Tetraodon nigroviridis	54.66	2.00e-141	495.00
IUUC-Tbe-127938	Tupaia belangeri	64.13	4.00e-113	400.00
IUUC-Ttr-128193	Tursiops truncatus	69.11	5.00e-168	583.00
IUUC-Vpa-130275	Vicugna pacos	70.23	0.00e+00	700.00
IUUC-Xtr-131982	Xenopus tropicalis	58.35	5.00e-166	577.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence