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Tag Content
iUUCD ID IUUC-Gga-040273
Ensembl Protein ID ENSGALP00000025281.6
UniProt Accession E1C765; E1C765_CHICK
Genbank Protein ID ENSGALP00000025281
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AADN04000201
Gene Name WHSC1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSGALG00000015705.6 ENSGALT00000025327.6 ENSGALP00000025281.6
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 2.70e-15 56.7 864 904
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 864  WCFVCSKGGS----LLCCESCPAAFHPDCLNIE----MPDGS-WYCNDCR 904
           8*********....*******************....9***8.******8 PP
   
Organism Gallus gallus
Protein Sequence
(Fasta)
MDFSIKRSSQ LLTRKINYLK MKQVPEILGN TNGKTQNCEV NRECSVYLGK AQLSATLQEG 60
VMQKYNGHDA LPFIPADKLK DLTSRVFNGE SGAQDAKLRF EPQEIKGVGT PPNTTPIKNG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Gga-040273|E3,PHD|Gallus gallus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGACTTTA GCATCAAAAG AAGTTCTCAA CTTTTAACTC GAAAAATTAA CTACTTAAAA 60
ATGAAGCAAG TACCAGAGAT CCTTGGAAAT ACCAATGGGA AAACTCAGAA TTGTGAAGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Gga-040273|E3,PHD|Gallus gallus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET
SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00184--RING
SM00317--SET
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002181 Ailuropoda melanoleuca 79.96 0.00e+00 2112.00
IUUC-Apl-003677 Anas platyrhynchos 94.99 0.00e+00 2535.00
IUUC-Aca-004278 Anolis carolinensis 81.83 0.00e+00 1553.00
IUUC-Ame-011932 Astyanax mexicanus 70.73 0.00e+00 1071.00
IUUC-Bta-012522 Bos taurus 75.33 0.00e+00 1982.00
IUUC-Cja-018908 Callithrix jacchus 78.41 0.00e+00 2066.00
IUUC-Cfa-020894 Canis familiaris 79.33 0.00e+00 2138.00
IUUC-Cpo-021982 Cavia porcellus 77.66 0.00e+00 2087.00
IUUC-Csa-023807 Chlorocebus sabaeus 79.40 0.00e+00 2101.00
IUUC-Cho-024405 Choloepus hoffmanni 58.60 2.00e-176 612.00
IUUC-Csv-026298 Ciona savignyi 37.46 1.00e-56 213.00
IUUC-Dre-027492 Danio rerio 73.59 0.00e+00 1118.00
IUUC-Dno-030020 Dasypus novemcinctus 76.38 0.00e+00 1830.00
IUUC-Dor-031103 Dipodomys ordii 71.79 0.00e+00 1859.00
IUUC-Ete-032488 Echinops telfairi 73.39 0.00e+00 1893.00
IUUC-Eca-034066 Equus caballus 80.69 0.00e+00 2170.00
IUUC-Eeu-035199 Erinaceus europaeus 60.76 0.00e+00 646.00
IUUC-Fca-035434 Felis catus 75.23 0.00e+00 1738.00
IUUC-Fal-037113 Ficedula albicollis 95.13 0.00e+00 2635.00
IUUC-Gmo-039686 Gadus morhua 68.48 0.00e+00 1035.00
IUUC-Gac-042123 Gasterosteus aculeatus 50.11 0.00e+00 1254.00
IUUC-Ggo-044643 Gorilla gorilla 79.11 0.00e+00 2111.00
IUUC-Hsa-046380 Homo sapiens 79.36 0.00e+00 2090.00
IUUC-Itr-048658 Ictidomys tridecemlineatus 84.79 0.00e+00 1332.00
IUUC-Lch-050217 Latimeria chalumnae 67.14 0.00e+00 1784.00
IUUC-Lpe-051661 Leersia perrieri 29.74 4.00e-12 67.00
IUUC-Loc-052766 Lepisosteus oculatus 54.25 0.00e+00 1394.00
IUUC-Laf-053780 Loxodonta africana 79.68 0.00e+00 2162.00
IUUC-Mcc-054928 Macaca mulatta 79.47 0.00e+00 2129.00
IUUC-Meu-056184 Macropus eugenii 74.39 0.00e+00 796.00
IUUC-Mga-059576 Meleagris gallopavo 95.56 0.00e+00 2554.00
IUUC-Mmr-061045 Microcebus murinus 79.66 0.00e+00 2154.00
IUUC-Mdo-062576 Monodelphis domestica 86.81 0.00e+00 2303.00
IUUC-Mmu-063640 Mus musculus 77.57 0.00e+00 2062.00
IUUC-Mac-065303 Musa acuminata 28.57 8.00e-11 62.00
IUUC-Mpu-066512 Mustela putorius furo 80.03 0.00e+00 2116.00
IUUC-Mlu-067280 Myotis lucifugus 75.50 0.00e+00 1043.00
IUUC-Nle-069896 Nomascus leucogenys 79.56 0.00e+00 2019.00
IUUC-Ont-072197 Oreochromis niloticus 73.85 0.00e+00 1055.00
IUUC-Oan-072724 Ornithorhynchus anatinus 84.80 0.00e+00 1434.00
IUUC-Ocu-074758 Oryctolagus cuniculus 76.71 0.00e+00 2022.00
IUUC-Ogl-077641 Oryza glaberrima 25.00 9.00e-11 60.80
IUUC-Ogu-078030 Oryza glumaepatula 28.43 3.00e-13 69.30
IUUC-Oin-079557 Oryza indica 25.00 8.00e-11 60.80
IUUC-Olo-080702 Oryza longistaminata 41.01 6.00e-44 172.00
IUUC-Opu-083371 Oryza punctata 44.22 5.00e-45 176.00
IUUC-Osa-085353 Oryza sativa 25.49 9.00e-11 60.80
IUUC-Oga-088702 Otolemur garnettii 80.18 0.00e+00 1870.00
IUUC-Oar-089736 Ovis aries 70.15 0.00e+00 1756.00
IUUC-Ptr-091055 Pan troglodytes 79.28 0.00e+00 2091.00
IUUC-Pan-092752 Papio anubis 87.50 0.00e+00 1322.00
IUUC-Psi-093620 Pelodiscus sinensis 89.90 0.00e+00 2456.00
IUUC-Ppa-095277 Physcomitrella patens 28.90 3.00e-11 63.20
IUUC-Pfo-097464 Poecilia formosa 65.31 0.00e+00 1071.00
IUUC-Pab-098051 Pongo abelii 79.43 0.00e+00 2119.00
IUUC-Pop-099927 Populus trichocarpa 28.27 2.00e-11 64.30
IUUC-Pca-100273 Procavia capensis 78.72 0.00e+00 2112.00
IUUC-Ppe-101635 Prunus persica 27.47 6.00e-11 62.80
IUUC-Pva-102473 Pteropus vampyrus 69.07 0.00e+00 1760.00
IUUC-Rno-105056 Rattus norvegicus 77.97 0.00e+00 2085.00
IUUC-Sha-107494 Sarcophilus harrisii 87.28 0.00e+00 2279.00
IUUC-Sit-110333 Setaria italica 27.81 7.00e-10 58.90
IUUC-Sar-113310 Sorex araneus 78.75 0.00e+00 1647.00
IUUC-Ssc-116344 Sus scrofa 73.49 0.00e+00 1964.00
IUUC-Tgu-116786 Taeniopygia guttata 93.60 0.00e+00 2511.00
IUUC-Tru-117638 Takifugu rubripes 50.55 0.00e+00 1248.00
IUUC-Tsy-118937 Tarsius syrichta 85.64 0.00e+00 1409.00
IUUC-Tni-120452 Tetraodon nigroviridis 63.68 0.00e+00 1068.00
IUUC-Tae-125237 Triticum aestivum 31.54 1.00e-06 47.00
IUUC-Tbe-127291 Tupaia belangeri 76.08 0.00e+00 1348.00
IUUC-Ttr-129017 Tursiops truncatus 71.08 0.00e+00 1525.00
IUUC-Xtr-132673 Xenopus tropicalis 66.64 0.00e+00 1779.00
IUUC-Xma-133695 Xiphophorus maculatus 68.11 0.00e+00 1024.00
Created Date 25-Jun-2017

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