iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-098488

Ensembl Protein ID

ENSPPYP00000008775.1

UniProt Accession

H2NS68; H2NS68_PONAB

Genbank Protein ID

ENSPPYP00000008775

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01205796

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000007789.1	ENSPPYT00000009134.1	ENSPPYP00000008775.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	9.80e-13	48.4	47	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 47   CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 106
           9*****************************77.......4566677678****************98 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MTFPEADILL KSGECAGQTM LDTMEAPGHS RQLLLQLNNQ RTKGFLCDVI IVVQNALFRA 60
HKNVLAASSA YLKSLVVHDN LLNLDHDMVS PAVFRLVLDF IYTGRLADGA EAAAAAAVAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTTTTC CTGAAGCGGA CATTTTACTT AAATCGGGTA ACTGTCTCCA AAAGGGTCAC 60
TTCGCCTGAA CAGTTTTCTT CTCGGAAGCC CCAGCACCCA GCCAGGTGCC CTGGGGCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	92.38	1.00e-153	536.00
IUUC-Aca-004680	Anolis carolinensis	57.10	1.00e-68	254.00
IUUC-Ame-010967	Astyanax mexicanus	60.24	5.00e-94	338.00
IUUC-Bta-013567	Bos taurus	94.97	0.00e+00	796.00
IUUC-Cja-019621	Callithrix jacchus	98.94	7.00e-47	178.00
IUUC-Cfa-020731	Canis familiaris	97.17	4.00e-171	595.00
IUUC-Cpo-021326	Cavia porcellus	91.70	4.00e-173	601.00
IUUC-Csa-023645	Chlorocebus sabaeus	98.90	5.00e-167	581.00
IUUC-Dre-028027	Danio rerio	57.64	1.00e-91	330.00
IUUC-Dno-028900	Dasypus novemcinctus	96.27	1.00e-164	573.00
IUUC-Fal-036980	Ficedula albicollis	61.56	5.00e-111	395.00
IUUC-Gga-040708	Gallus gallus	70.61	1.00e-105	377.00
IUUC-Ggo-044591	Gorilla gorilla	100.00	3.00e-140	492.00
IUUC-Hsa-046769	Homo sapiens	99.34	2.00e-163	569.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	97.50	3.00e-174	605.00
IUUC-Loc-051883	Lepisosteus oculatus	63.47	2.00e-93	336.00
IUUC-Laf-053358	Loxodonta africana	88.46	0.00e+00	791.00
IUUC-Mcc-054981	Macaca mulatta	98.90	8.00e-167	580.00
IUUC-Meu-056181	Macropus eugenii	89.31	4.00e-65	241.00
IUUC-Mga-059592	Meleagris gallopavo	73.54	2.00e-102	366.00
IUUC-Mmr-061560	Microcebus murinus	96.05	3.00e-163	568.00
IUUC-Mdo-062511	Monodelphis domestica	81.45	5.00e-91	328.00
IUUC-Mmu-064258	Mus musculus	96.27	5.00e-161	561.00
IUUC-Mpu-065911	Mustela putorius furo	97.14	5.00e-168	584.00
IUUC-Mlu-067575	Myotis lucifugus	81.43	0.00e+00	652.00
IUUC-Ont-072493	Oreochromis niloticus	65.97	2.00e-80	293.00
IUUC-Ola-086584	Oryzias latipes	61.66	2.00e-89	323.00
IUUC-Oga-088774	Otolemur garnettii	96.27	2.00e-175	608.00
IUUC-Ptr-090491	Pan troglodytes	100.00	4.00e-122	431.00
IUUC-Pma-094179	Petromyzon marinus	70.51	4.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	58.86	6.00e-87	315.00
IUUC-Pca-100667	Procavia capensis	96.61	2.00e-143	502.00
IUUC-Pva-102421	Pteropus vampyrus	96.26	2.00e-166	579.00
IUUC-Rno-105528	Rattus norvegicus	95.82	6.00e-153	534.00
IUUC-Sar-113478	Sorex araneus	99.17	6.00e-120	424.00
IUUC-Ssc-115420	Sus scrofa	90.35	8.00e-168	583.00
IUUC-Tgu-116642	Taeniopygia guttata	71.88	8.00e-107	380.00
IUUC-Tru-118583	Takifugu rubripes	60.44	2.00e-85	310.00
IUUC-Xtr-132210	Xenopus tropicalis	57.72	2.00e-116	413.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence