iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118274

UUCD1 version

UUC-TaR-00219

Ensembl Protein ID

ENSTRUP00000011637.1

UniProt Accession

H2SGV5; H2SGV5_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000004874.1	ENSTRUT00000011697.1	ENSTRUP00000011637.1
ENSTRUG00000004874.1	ENSTRUT00000011698.1	ENSTRUP00000011638.1
ENSTRUG00000004874.1	ENSTRUT00000011699.1	ENSTRUP00000011639.1
ENSTRUG00000004874.1	ENSTRUT00000011700.1	ENSTRUP00000011640.1
ENSTRUG00000004874.1	ENSTRUT00000011701.1	ENSTRUP00000011641.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.10e-08	36.7	389	427
E3 activity/RING/U-box	5.70e-11	43.6	384	432

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           Ca+C+  f + p+++pCgH+f+++Cl++          + +CPlC+
   Q: 389  CALCMRLFYE-PVTTPCGHTFCKTCLERC------LDHTPHCPLCK 427
           ****999977.***************999......9*********6 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplte 52
           p +f C++ + l+ +Pv++p+G+t+ ++++e++l++  + cP+++++l++
   Q: 384  PNDFECALCMRLFYEPVTTPCGHTFCKTCLERCLDHTPH-CPLCKESLKQ 432
           789************************************.*******986 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

LQKANALASE NCLKEAIDCV SLAMRYGPVR PDELSVVVDC IFRNFKSKLA GPDAGPGQSG 60
DTCGDSIFDC PNCRGFLAEP VTLACGHSYC KRCLHRRLLS KCKLCDEVVK GEEKLNITLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTACAGAAAG CTAACGCTTT AGCTTCCGAA AACTGCCTCA AAGAAGCCAT CGACTGTGTG 60
TCACTAGCTA TGCGCTACGG GCCCGTACGA CCCGATGAGT TAAGCGTCGT TGTGGACTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR011990--TPR-like_helical_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51787--LON_N
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02190--LON_substr_bdg
PF13445--zf-RING_UBOX

SMART

SM00464--LON
SM00184--RING

Gene Ontology

GO:0005622--C:intracellular
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001989	Ailuropoda melanoleuca	57.96	6.00e-169	587.00
IUUC-Atr-002972	Amborella trichopoda	41.26	1.00e-44	174.00
IUUC-Apl-003309	Anas platyrhynchos	67.45	3.00e-145	508.00
IUUC-Aca-004288	Anolis carolinensis	52.10	1.00e-179	623.00
IUUC-Aly-005476	Arabidopsis lyrata	35.46	2.00e-39	157.00
IUUC-Ath-006654	Arabidopsis thaliana	35.83	3.00e-40	159.00
IUUC-Acl-008224	Aspergillus clavatus	30.75	2.00e-40	160.00
IUUC-Ani-009473	Aspergillus nidulans	31.90	1.00e-42	167.00
IUUC-Ate-010489	Aspergillus terreus	30.34	4.00e-40	159.00
IUUC-Ame-010716	Astyanax mexicanus	58.91	0.00e+00	811.00
IUUC-Bta-012903	Bos taurus	54.58	5.00e-169	587.00
IUUC-Bdi-014333	Brachypodium distachyon	41.44	2.00e-43	170.00
IUUC-Bol-016442	Brassica oleracea	33.02	6.00e-43	168.00
IUUC-Bra-016716	Brassica rapa	35.09	2.00e-38	154.00
IUUC-Cja-019312	Callithrix jacchus	51.13	1.00e-177	616.00
IUUC-Cfa-020159	Canis familiaris	55.59	2.00e-175	609.00
IUUC-Cpo-022528	Cavia porcellus	57.06	9.00e-161	560.00
IUUC-Csa-023361	Chlorocebus sabaeus	52.53	1.00e-166	580.00
IUUC-Cho-024549	Choloepus hoffmanni	51.21	3.00e-133	468.00
IUUC-Cin-025668	Ciona intestinalis	33.23	2.00e-97	349.00
IUUC-Cme-027153	Cyanidioschyzon merolae	30.42	7.00e-27	115.00
IUUC-Dre-028195	Danio rerio	58.48	0.00e+00	813.00
IUUC-Dno-029284	Dasypus novemcinctus	57.06	6.00e-170	590.00
IUUC-Dor-031123	Dipodomys ordii	54.79	4.00e-132	465.00
IUUC-Dse-031331	Dothistroma septosporum	32.71	7.00e-40	158.00
IUUC-Ete-032455	Echinops telfairi	67.36	2.00e-149	521.00
IUUC-Eca-033248	Equus caballus	65.28	1.00e-141	496.00
IUUC-Eeu-034441	Erinaceus europaeus	65.54	8.00e-148	516.00
IUUC-Fca-035551	Felis catus	57.78	1.00e-170	592.00
IUUC-Fal-036731	Ficedula albicollis	59.89	1.00e-177	615.00
IUUC-Gmo-039315	Gadus morhua	62.13	0.00e+00	814.00
IUUC-Gga-040888	Gallus gallus	68.49	1.00e-155	542.00
IUUC-Gac-042121	Gasterosteus aculeatus	71.57	0.00e+00	994.00
IUUC-Ggo-044985	Gorilla gorilla	57.33	2.00e-168	585.00
IUUC-Hsa-046592	Homo sapiens	50.86	2.00e-171	596.00
IUUC-Hvu-047145	Hordeum vulgare	43.44	6.00e-27	114.00
IUUC-Itr-048573	Ictidomys tridecemlineatus	54.17	5.00e-170	591.00
IUUC-Lch-050404	Latimeria chalumnae	52.17	0.00e+00	674.00
IUUC-Laf-053431	Loxodonta africana	59.67	1.00e-176	613.00
IUUC-Mcc-055751	Macaca mulatta	52.36	2.00e-165	576.00
IUUC-Mvi-060228	Microbotryum violaceum	33.14	2.00e-47	184.00
IUUC-Mmr-061283	Microcebus murinus	50.92	6.00e-170	590.00
IUUC-Mmu-063169	Mus musculus	53.31	3.00e-171	595.00
IUUC-Mac-065566	Musa acuminata	37.28	2.00e-43	170.00
IUUC-Mpu-066537	Mustela putorius furo	52.27	5.00e-173	601.00
IUUC-Mlu-067497	Myotis lucifugus	56.88	2.00e-167	582.00
IUUC-Nle-068971	Nomascus leucogenys	57.30	8.00e-168	583.00
IUUC-Opr-070791	Ochotona princeps	61.39	3.00e-161	561.00
IUUC-Ont-071548	Oreochromis niloticus	70.39	0.00e+00	995.00
IUUC-Oan-072747	Ornithorhynchus anatinus	66.58	1.00e-152	532.00
IUUC-Ocu-074928	Oryctolagus cuniculus	67.10	6.00e-149	520.00
IUUC-Oba-075239	Oryza barthii	41.96	2.00e-45	176.00
IUUC-Obr-076158	Oryza brachyantha	41.44	3.00e-44	172.00
IUUC-Ogu-078154	Oryza glumaepatula	41.63	2.00e-45	177.00
IUUC-Oin-079067	Oryza indica	40.51	2.00e-45	177.00
IUUC-Olo-080663	Oryza longistaminata	41.96	2.00e-45	176.00
IUUC-Oni-082119	Oryza nivara	41.23	2.00e-45	177.00
IUUC-Opu-083266	Oryza punctata	36.32	4.00e-33	135.00
IUUC-Oru-085190	Oryza rufipogon	41.96	3.00e-45	176.00
IUUC-Ola-086977	Oryzias latipes	69.96	0.00e+00	968.00
IUUC-Oga-088719	Otolemur garnettii	50.64	4.00e-174	604.00
IUUC-Oar-089577	Ovis aries	57.43	6.00e-169	587.00
IUUC-Ptr-090711	Pan troglodytes	52.22	1.00e-170	593.00
IUUC-Pan-092587	Papio anubis	52.22	2.00e-166	579.00
IUUC-Psi-093128	Pelodiscus sinensis	55.52	1.00e-172	599.00
IUUC-Pfo-096474	Poecilia formosa	69.75	0.00e+00	998.00
IUUC-Pab-097800	Pongo abelii	51.15	3.00e-172	598.00
IUUC-Pop-100044	Populus trichocarpa	35.14	2.00e-44	172.00
IUUC-Pca-100905	Procavia capensis	37.12	1.00e-98	354.00
IUUC-Ppe-101621	Prunus persica	37.45	3.00e-39	156.00
IUUC-Pgr-103289	Puccinia graminis	27.54	5.00e-31	129.00
IUUC-Ptt-103898	Puccinia triticina	27.03	4.00e-29	122.00
IUUC-Pyt-104565	Pyrenophora triticirepentis	33.23	3.00e-36	146.00
IUUC-Rno-105718	Rattus norvegicus	57.14	2.00e-164	572.00
IUUC-Sha-107565	Sarcophilus harrisii	37.20	4.00e-118	419.00
IUUC-Spo-108344	Schizosaccharomyces pombe	25.98	4.00e-24	105.00
IUUC-Sit-110495	Setaria italica	41.70	6.00e-45	175.00
IUUC-Sar-113220	Sorex araneus	63.99	6.00e-139	487.00
IUUC-Sbi-114779	Sorghum bicolor	40.70	1.00e-29	124.00
IUUC-Ssc-115733	Sus scrofa	50.85	2.00e-175	609.00
IUUC-Tgu-117431	Taeniopygia guttata	54.46	2.00e-177	615.00
IUUC-Tsy-119043	Tarsius syrichta	50.51	7.00e-174	603.00
IUUC-Tni-120766	Tetraodon nigroviridis	75.15	0.00e+00	977.00
IUUC-Tca-121632	Theobroma cacao	34.68	6.00e-46	178.00
IUUC-Tae-124676	Triticum aestivum	35.86	5.00e-44	172.00
IUUC-Tur-126297	Triticum urartu	42.94	5.00e-33	135.00
IUUC-Tbe-127284	Tupaia belangeri	66.06	1.00e-144	505.00
IUUC-Vpa-130408	Vicugna pacos	60.89	1.00e-146	513.00
IUUC-Vvi-130910	Vitis vinifera	34.68	1.00e-41	163.00
IUUC-Xtr-132417	Xenopus tropicalis	50.30	2.00e-176	612.00
IUUC-Xma-134099	Xiphophorus maculatus	68.72	0.00e+00	979.00
IUUC-Zma-135914	Zea mays	42.62	1.00e-25	110.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence