iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036374

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02078556

Gene Name

CISH

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000021968.1	ENSFCAT00000028298.1	ENSFCAP00000017378.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.60e-15	55.6	209	256

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 1    lsklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           l++++++rs+ rSLqhLCRl+I+r++ +     +d+LPLP+++ dYL+++++q
   Q: 209  LVQPFVRRSSARSLQHLCRLVINRLVAD-----VDCLPLPRRMADYLRQYPFQ 256
           57999***********************.....8****************986 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MVLCVQGPCS LLAVEQIGQR PLWTQSLELP EPAMQPLPAG SFLEEVAEET PAQPESEPKV 60
LDPEEDLLCI AKTFSYLRES GWYWGSITAS EARQHLQKMP EGTFLVRDST HPSYLFTLSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCCCCAGC GCCCTCCCGG CCAGCCAGCG CCTTGGCCTC TCATTCCCAT CCCGTCGCCG 60
GTGCGCCCTG GGAGCCTGCC TTACGAGCGA GACCTGCGCC CACGGGCTCC CTCCAGCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028425--CIS
IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0007205--P:protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016567--P:protein ubiquitination

KEGG

fca:101096550

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001189	Ailuropoda melanoleuca	96.43	4.00e-129	453.00
IUUC-Aca-004372	Anolis carolinensis	63.08	5.00e-86	310.00
IUUC-Ame-010787	Astyanax mexicanus	46.12	4.00e-52	197.00
IUUC-Bta-012826	Bos taurus	91.44	1.00e-130	458.00
IUUC-Cja-020004	Callithrix jacchus	90.04	1.00e-112	398.00
IUUC-Cfa-020150	Canis familiaris	94.00	5.00e-117	413.00
IUUC-Csa-023173	Chlorocebus sabaeus	89.64	8.00e-113	399.00
IUUC-Dre-028606	Danio rerio	44.63	9.00e-34	136.00
IUUC-Dno-028956	Dasypus novemcinctus	89.45	5.00e-126	442.00
IUUC-Dor-030148	Dipodomys ordii	74.71	4.00e-100	357.00
IUUC-Ete-032313	Echinops telfairi	84.38	6.00e-104	369.00
IUUC-Eca-033422	Equus caballus	96.89	1.00e-138	485.00
IUUC-Eeu-034806	Erinaceus europaeus	93.60	4.00e-114	403.00
IUUC-Fal-036801	Ficedula albicollis	65.77	3.00e-87	314.00
IUUC-Gmo-038483	Gadus morhua	39.15	4.00e-36	144.00
IUUC-Gga-040891	Gallus gallus	67.18	4.00e-83	300.00
IUUC-Gac-042147	Gasterosteus aculeatus	41.31	4.00e-37	147.00
IUUC-Ggo-045511	Gorilla gorilla	90.44	2.00e-114	405.00
IUUC-Hsa-046678	Homo sapiens	90.31	3.00e-118	417.00
IUUC-Itr-048397	Ictidomys tridecemlineatus	94.94	3.00e-136	477.00
IUUC-Lch-050555	Latimeria chalumnae	56.11	2.00e-70	258.00
IUUC-Laf-054141	Loxodonta africana	90.70	4.00e-128	450.00
IUUC-Mcc-055401	Macaca mulatta	88.84	5.00e-111	393.00
IUUC-Meu-056592	Macropus eugenii	70.12	1.00e-89	322.00
IUUC-Mga-059515	Meleagris gallopavo	73.76	7.00e-79	286.00
IUUC-Mmr-060848	Microcebus murinus	95.20	7.00e-121	426.00
IUUC-Mdo-062720	Monodelphis domestica	68.87	7.00e-91	326.00
IUUC-Mmu-063348	Mus musculus	90.66	4.00e-130	456.00
IUUC-Mpu-065834	Mustela putorius furo	95.72	1.00e-130	458.00
IUUC-Mlu-067687	Myotis lucifugus	89.11	5.00e-106	376.00
IUUC-Nle-069277	Nomascus leucogenys	89.53	2.00e-115	408.00
IUUC-Ont-071890	Oreochromis niloticus	46.60	3.00e-36	144.00
IUUC-Oan-073672	Ornithorhynchus anatinus	66.41	5.00e-88	317.00
IUUC-Ocu-073875	Oryctolagus cuniculus	92.80	1.00e-126	445.00
IUUC-Ola-087140	Oryzias latipes	45.03	9.00e-25	105.00
IUUC-Oga-087943	Otolemur garnettii	92.61	7.00e-127	446.00
IUUC-Oar-090194	Ovis aries	90.87	5.00e-127	446.00
IUUC-Ptr-090934	Pan troglodytes	89.64	3.00e-112	397.00
IUUC-Pan-092121	Papio anubis	89.15	1.00e-115	409.00
IUUC-Psi-093733	Pelodiscus sinensis	63.49	1.00e-82	298.00
IUUC-Pfo-096313	Poecilia formosa	47.80	2.00e-43	168.00
IUUC-Pab-098439	Pongo abelii	90.31	1.00e-117	415.00
IUUC-Pca-101010	Procavia capensis	89.53	1.00e-125	442.00
IUUC-Pva-103112	Pteropus vampyrus	92.61	2.00e-122	431.00
IUUC-Rno-105917	Rattus norvegicus	91.83	7.00e-123	432.00
IUUC-Sha-106954	Sarcophilus harrisii	68.08	7.00e-92	329.00
IUUC-Smo-109292	Selaginella moellendorffii	31.15	1.70e-01	30.80
IUUC-Sar-113001	Sorex araneus	93.60	9.00e-124	435.00
IUUC-Ssc-115922	Sus scrofa	93.62	7.00e-67	245.00
IUUC-Tgu-117338	Taeniopygia guttata	65.61	9.00e-84	302.00
IUUC-Tru-118511	Takifugu rubripes	44.69	2.00e-33	135.00
IUUC-Tsy-119434	Tarsius syrichta	93.20	1.00e-118	418.00
IUUC-Tni-119837	Tetraodon nigroviridis	43.37	2.00e-29	122.00
IUUC-Ttr-128340	Tursiops truncatus	80.54	4.00e-85	307.00
IUUC-Vpa-130443	Vicugna pacos	93.77	3.00e-133	467.00
IUUC-Xtr-131784	Xenopus tropicalis	52.90	1.00e-68	252.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence