iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.30e-10	40.9	504	549

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C vC+++g+    l++C+ C++++H +Cl+++  ++ p+   wiCp+C++
   Q: 504  DFCSVCRKSGQ----LLMCDTCSRVYHLDCLEPP-LKTIPKGM-WICPRCQD 549
           79*********....*******************.*******7.******85 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MELQTLQEAL KVEIQVHQKL VAQMKQDPQN ADLKKQLHEL QAKITALSEK QKRVVEQLRK 60
NLIVKQEQPD KFQIQPLSQS ENKLQTAQQQ PLQPLQQQQQ QQQQQQQQQQ QQQQQQQQQH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAATATAAT ATTTCTAATT TAATTATTTT GACAAAAATT TTCTTCATTC CCAATGATCC 60
CAAACATTGT ATGATTTCTC CAGCTGCAGC AACAAGAGGA GCTGGTAATT TTAAACGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:1990391--C:DNA repair complex
GO:0000118--C:histone deacetylase complex
GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0042393--F:histone binding
GO:0000977--F:RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003712--F:transcription cofactor activity
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated

KEGG

rno:362166

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001656	Ailuropoda melanoleuca	92.08	0.00e+00	1016.00
IUUC-Atr-002930	Amborella trichopoda	46.43	5.00e-10	60.50
IUUC-Apl-003874	Anas platyrhynchos	86.70	0.00e+00	997.00
IUUC-Aca-004684	Anolis carolinensis	84.93	0.00e+00	695.00
IUUC-Ame-010638	Astyanax mexicanus	65.05	5.00e-127	448.00
IUUC-Bgr-012025	Blumeria graminis	37.04	2.00e-08	55.50
IUUC-Bta-013460	Bos taurus	93.31	0.00e+00	990.00
IUUC-Cja-019170	Callithrix jacchus	92.81	0.00e+00	1102.00
IUUC-Cfa-020760	Canis familiaris	92.81	0.00e+00	1122.00
IUUC-Cpo-021549	Cavia porcellus	91.81	0.00e+00	1075.00
IUUC-Csa-023461	Chlorocebus sabaeus	93.93	0.00e+00	999.00
IUUC-Cne-026966	Cryptococcus neoformans	46.43	2.00e-11	63.90
IUUC-Dre-027928	Danio rerio	55.82	2.00e-155	542.00
IUUC-Dno-029450	Dasypus novemcinctus	93.08	0.00e+00	957.00
IUUC-Dor-030699	Dipodomys ordii	92.66	0.00e+00	1129.00
IUUC-Ete-033073	Echinops telfairi	89.26	0.00e+00	715.00
IUUC-Eca-033822	Equus caballus	90.84	0.00e+00	1010.00
IUUC-Fca-035562	Felis catus	92.52	0.00e+00	1112.00
IUUC-Fal-037269	Ficedula albicollis	86.53	0.00e+00	1044.00
IUUC-Gmo-038592	Gadus morhua	56.24	7.00e-122	431.00
IUUC-Gga-040795	Gallus gallus	87.11	0.00e+00	1052.00
IUUC-Gac-042224	Gasterosteus aculeatus	61.52	1.00e-144	506.00
IUUC-Ggo-045327	Gorilla gorilla	93.67	0.00e+00	1114.00
IUUC-Hsa-046675	Homo sapiens	93.53	0.00e+00	1108.00
IUUC-Itr-048946	Ictidomys tridecemlineatus	93.16	0.00e+00	655.00
IUUC-Lch-050609	Latimeria chalumnae	71.08	0.00e+00	767.00
IUUC-Loc-052407	Lepisosteus oculatus	74.17	0.00e+00	662.00
IUUC-Laf-053876	Loxodonta africana	92.55	0.00e+00	1009.00
IUUC-Mcc-054954	Macaca mulatta	90.97	0.00e+00	1071.00
IUUC-Meu-056821	Macropus eugenii	81.29	0.00e+00	983.00
IUUC-Mtr-058324	Medicago truncatula	40.58	2.00e-10	62.00
IUUC-Mga-059320	Meleagris gallopavo	86.52	0.00e+00	1001.00
IUUC-Mmr-061278	Microcebus murinus	88.83	0.00e+00	1058.00
IUUC-Mdo-062891	Monodelphis domestica	89.63	0.00e+00	1094.00
IUUC-Mmu-063907	Mus musculus	95.68	0.00e+00	1109.00
IUUC-Mac-065599	Musa acuminata	40.85	1.00e-11	65.50
IUUC-Mpu-065839	Mustela putorius furo	92.52	0.00e+00	1112.00
IUUC-Mlu-068142	Myotis lucifugus	92.81	0.00e+00	1105.00
IUUC-Ncr-068727	Neurospora crassa	41.27	2.00e-10	62.00
IUUC-Nle-069423	Nomascus leucogenys	93.38	0.00e+00	1110.00
IUUC-Opr-070236	Ochotona princeps	87.17	0.00e+00	832.00
IUUC-Ont-071327	Oreochromis niloticus	57.61	8.00e-126	444.00
IUUC-Oan-073405	Ornithorhynchus anatinus	95.42	0.00e+00	927.00
IUUC-Ocu-074391	Oryctolagus cuniculus	91.68	0.00e+00	1093.00
IUUC-Ola-086548	Oryzias latipes	61.51	1.00e-146	513.00
IUUC-Oga-088488	Otolemur garnettii	93.53	0.00e+00	1114.00
IUUC-Oar-090334	Ovis aries	94.27	0.00e+00	1099.00
IUUC-Ptr-091018	Pan troglodytes	93.53	0.00e+00	1108.00
IUUC-Psi-093596	Pelodiscus sinensis	89.45	0.00e+00	872.00
IUUC-Pma-094616	Petromyzon marinus	63.67	2.00e-99	355.00
IUUC-Pfo-097233	Poecilia formosa	59.17	5.00e-133	468.00
IUUC-Pab-097801	Pongo abelii	93.53	0.00e+00	1113.00
IUUC-Pop-099691	Populus trichocarpa	44.29	8.00e-12	65.90
IUUC-Ppe-101956	Prunus persica	47.83	2.00e-13	71.20
IUUC-Pva-102419	Pteropus vampyrus	93.25	0.00e+00	1116.00
IUUC-Pyt-104775	Pyrenophora triticirepentis	36.36	6.00e-12	66.60
IUUC-Sha-107328	Sarcophilus harrisii	91.39	0.00e+00	1022.00
IUUC-Sar-113573	Sorex araneus	96.90	0.00e+00	744.00
IUUC-Ssc-115924	Sus scrofa	97.16	0.00e+00	944.00
IUUC-Tgu-117422	Taeniopygia guttata	86.68	0.00e+00	1041.00
IUUC-Tru-118697	Takifugu rubripes	59.52	1.00e-127	450.00
IUUC-Tsy-119092	Tarsius syrichta	93.98	3.00e-171	595.00
IUUC-Tni-120185	Tetraodon nigroviridis	61.65	2.00e-130	459.00
IUUC-Tca-121730	Theobroma cacao	46.55	6.00e-11	63.20
IUUC-Ttr-128860	Tursiops truncatus	91.70	0.00e+00	1114.00
IUUC-Vpa-130333	Vicugna pacos	88.08	0.00e+00	1057.00
IUUC-Xtr-131763	Xenopus tropicalis	72.28	0.00e+00	710.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence