iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004753

UUCD1 version

UUC-AnC-01028

Ensembl Protein ID

ENSACAP00000010331.3

UniProt Accession

G1KK79; G1KK79_ANOCA

Protein Name

Uncharacterized protein

Gene Name

USP25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000010500.3	ENSACAT00000010543.3	ENSACAP00000010331.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-19	70.3	19	365

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 162  vssreepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRf..sfseeqksrek 248
           + +  e f +++l+v+g +     +l++cLe+ + e e+e+   +++e+  k+ +   ++++  lP+ +++  + f  + s+ q +  k
   Q: 19   KFENAEMFGQYPLQVNGFK-----DLHECLEAAMVEGEIES---LHSENSGKSGQEIWMTQI-MLPPLISFIVSQFilTASKIQPKLYK 98
           4467899999********9.....9**************96...999999988865555555.69***********7777888888899 PP
   S: 249  inkkvefpleLdlspfcts...................................................................... 267
           ++++ ef l++ + ++ +                                                                       
   Q: 99   MHTEAEFFLSFYIYRYSSCyflskrvtisnllrsmtriyrnghrcpkrgiavsikeltyyfemlkfqkaseilglmdgmasqvaslmlp 187
           99999999999999888778899999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 268  .........................................peekqke......................................... 274
                                                          +                                         
   Q: 188  aslahyscavehnsskkcstteqqgpstemqstspaqrsviH-----Kpftqsrippdlpmhpaprhiteeelsvlegclhrwrteven 271
           999999999888887777777666666655555555555550.....055555555555555555555555555666666666666666 PP
   S: 275  ..........................kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staY 331
                                     ++ Y+L+av+vH+G+++ GHY+ay++++ ++ W++++D +Vt +++ee ++++      ++aY
   Q: 272  dtrdlqesiariqrtielmysdksmvQVPYRLHAVLVHEGQANAGHYWAYIYDSYQRrWMKYNDISVTRSTWEELERDSFggyrnASAY 360
           66666677777777777777777777***************************76667*******************8779******** PP
   S: 332  vlfYk 336
           +l+Y 
   Q: 361  CLMYI 365
           ****6 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MVELFYGRFL AVGVLEGKKF ENAEMFGQYP LQVNGFKDLH ECLEAAMVEG EIESLHSENS 60
GKSGQEIWMT QIMLPPLISF IVSQFILTAS KIQPKLYKMH TEAEFFLSFY IYRYSSCYFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTATCTGAG TCCACACTGC CATATATTCG TGCTCAAAGT AGGAACTGTG GGATTTTATT 60
CAGCTGTGTG GAAGGGGGCT TTCATTTACA CACAAATTCA ACTGGAGAAC AAACCCTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1904293--P:negative regulation of ERAD pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001340	Ailuropoda melanoleuca	67.32	0.00e+00	1055.00
IUUC-Apl-004030	Anas platyrhynchos	72.67	0.00e+00	1153.00
IUUC-Ame-010624	Astyanax mexicanus	62.33	0.00e+00	976.00
IUUC-Bta-013166	Bos taurus	64.91	0.00e+00	979.00
IUUC-Cja-019150	Callithrix jacchus	63.60	0.00e+00	1024.00
IUUC-Cfa-020649	Canis familiaris	63.85	0.00e+00	1034.00
IUUC-Cpo-021807	Cavia porcellus	67.78	0.00e+00	1087.00
IUUC-Csa-023388	Chlorocebus sabaeus	62.95	0.00e+00	1032.00
IUUC-Cgl-026575	Colletotrichum gloeosporioides	53.33	3.00e-09	57.80
IUUC-Dno-029495	Dasypus novemcinctus	64.32	0.00e+00	1047.00
IUUC-Dor-030948	Dipodomys ordii	62.41	0.00e+00	976.00
IUUC-Eca-033214	Equus caballus	71.33	0.00e+00	774.00
IUUC-Fca-035876	Felis catus	65.76	0.00e+00	998.00
IUUC-Fox-037752	Fusarium oxysporum	33.79	5.00e-13	70.50
IUUC-Fso-038114	Fusarium solani	36.45	5.00e-12	67.40
IUUC-Gmo-039490	Gadus morhua	61.15	0.00e+00	933.00
IUUC-Gga-040817	Gallus gallus	69.16	0.00e+00	1129.00
IUUC-Gac-042473	Gasterosteus aculeatus	60.86	0.00e+00	967.00
IUUC-Ggo-044939	Gorilla gorilla	64.05	0.00e+00	999.00
IUUC-Hsa-046204	Homo sapiens	62.94	0.00e+00	973.00
IUUC-Itr-048276	Ictidomys tridecemlineatus	43.10	2.00e-145	509.00
IUUC-Lch-049572	Latimeria chalumnae	63.65	0.00e+00	1008.00
IUUC-Loc-052070	Lepisosteus oculatus	62.95	0.00e+00	1000.00
IUUC-Lma-053078	Leptosphaeria maculans	31.48	5.00e-11	63.90
IUUC-Laf-054426	Loxodonta africana	65.19	0.00e+00	978.00
IUUC-Mcc-055858	Macaca mulatta	62.95	0.00e+00	1031.00
IUUC-Mga-059808	Meleagris gallopavo	69.07	0.00e+00	1068.00
IUUC-Mmr-060987	Microcebus murinus	64.86	0.00e+00	1040.00
IUUC-Mmu-064245	Mus musculus	62.06	0.00e+00	970.00
IUUC-Mpu-066304	Mustela putorius furo	63.26	0.00e+00	1032.00
IUUC-Mlu-067139	Myotis lucifugus	63.76	0.00e+00	995.00
IUUC-Nle-069075	Nomascus leucogenys	62.94	0.00e+00	968.00
IUUC-Oan-073054	Ornithorhynchus anatinus	63.98	0.00e+00	962.00
IUUC-Ocu-074102	Oryctolagus cuniculus	65.21	0.00e+00	1041.00
IUUC-Ola-086529	Oryzias latipes	67.02	0.00e+00	807.00
IUUC-Oga-088939	Otolemur garnettii	64.99	0.00e+00	996.00
IUUC-Oar-090266	Ovis aries	64.36	0.00e+00	1034.00
IUUC-Ptr-090546	Pan troglodytes	62.94	0.00e+00	974.00
IUUC-Pan-092311	Papio anubis	62.84	0.00e+00	1030.00
IUUC-Pfo-096726	Poecilia formosa	56.51	0.00e+00	957.00
IUUC-Pab-097608	Pongo abelii	66.26	0.00e+00	1047.00
IUUC-Pca-100718	Procavia capensis	54.36	0.00e+00	649.00
IUUC-Pva-103150	Pteropus vampyrus	67.57	0.00e+00	1035.00
IUUC-Pyt-104434	Pyrenophora triticirepentis	42.62	3.00e-10	61.20
IUUC-Rno-105727	Rattus norvegicus	62.65	0.00e+00	957.00
IUUC-Sha-107051	Sarcophilus harrisii	65.88	0.00e+00	1028.00
IUUC-Sar-113097	Sorex araneus	65.88	0.00e+00	1045.00
IUUC-Ssc-115877	Sus scrofa	62.68	0.00e+00	956.00
IUUC-Tgu-117473	Taeniopygia guttata	64.00	0.00e+00	961.00
IUUC-Tru-118135	Takifugu rubripes	58.19	0.00e+00	667.00
IUUC-Tsy-119471	Tarsius syrichta	66.09	0.00e+00	1038.00
IUUC-Tme-126928	Tuber melanosporum	31.43	8.00e-10	59.70
IUUC-Tbe-127549	Tupaia belangeri	65.72	0.00e+00	1004.00
IUUC-Ttr-128896	Tursiops truncatus	76.21	0.00e+00	936.00
IUUC-Vpa-130500	Vicugna pacos	64.23	0.00e+00	974.00
IUUC-Xtr-132896	Xenopus tropicalis	63.30	0.00e+00	989.00
IUUC-Xma-133349	Xiphophorus maculatus	58.40	0.00e+00	929.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence