iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020040

Ensembl Protein ID

ENSCAFP00000003069.3

UniProt Accession

F1PUU5; F1PUU5_CANLF

Genbank Protein ID

ENSCAFP00000003069

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03008380

Gene Name

CD2AP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000002089.3	ENSCAFT00000003306.3	ENSCAFP00000003069.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.60e-66	218.5	284	342

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +ke++++l+ ye++n+deL++k+G+++++i+ke+ ++gW+kg  el+gk+G+fP+nF  ++
   Q: 284  AKEYCRTLFAYEGTNEDELSFKEGEIIHLISKETGEAGWWKG--ELNGKEGVFPDNFAIQI 342
           689***************************************..9************9877 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MLSIFQYLIS TGAFWVDYIV EYDYDAVHDD ELTIRVGEII RNVKKLQEEG WLEGELNGRR 60
GMFPDNFVKE IKRETEPKDD NLPIKRERHG NVASLVQRIS TYGLPAGGIQ PHPQTKNIKK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAGGCTCCA TGCAGGAAGC ATGATGTGGG ACTCCATCCC AGGACTTGGG GGTCACGCCC 60
TGAGCCAAAG GCAGACACTC AACCGCCGGA GCCACCCAGG TGTCTCACTT CAATACATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028445--CD2AP
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0031941--C:filamentous actin
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0032911--P:negative regulation of transforming growth factor beta1 production
GO:1900182--P:positive regulation of protein localization to nucleus
GO:2000249--P:regulation of actin cytoskeleton reorganization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001574	Ailuropoda melanoleuca	93.44	0.00e+00	1018.00
IUUC-Apl-003573	Anas platyrhynchos	63.97	1.00e-162	566.00
IUUC-Aca-005118	Anolis carolinensis	64.47	4.00e-169	588.00
IUUC-Ame-010657	Astyanax mexicanus	52.69	2.00e-89	323.00
IUUC-Bta-012577	Bos taurus	86.76	0.00e+00	879.00
IUUC-Cja-020010	Callithrix jacchus	90.75	0.00e+00	964.00
IUUC-Cpo-021906	Cavia porcellus	81.93	0.00e+00	815.00
IUUC-Csa-024008	Chlorocebus sabaeus	91.22	0.00e+00	926.00
IUUC-Cho-024359	Choloepus hoffmanni	76.79	2.00e-65	243.00
IUUC-Csv-026228	Ciona savignyi	40.37	4.00e-24	103.00
IUUC-Dre-027661	Danio rerio	55.52	2.00e-93	337.00
IUUC-Dno-029568	Dasypus novemcinctus	87.97	0.00e+00	884.00
IUUC-Dor-030286	Dipodomys ordii	77.27	0.00e+00	722.00
IUUC-Ete-032576	Echinops telfairi	67.33	3.00e-180	624.00
IUUC-Eca-033438	Equus caballus	92.16	0.00e+00	997.00
IUUC-Eeu-034588	Erinaceus europaeus	73.21	1.00e-150	526.00
IUUC-Fca-036597	Felis catus	94.84	0.00e+00	1031.00
IUUC-Fal-037305	Ficedula albicollis	63.26	1.00e-165	576.00
IUUC-Gmo-039516	Gadus morhua	46.04	6.00e-65	241.00
IUUC-Gga-040979	Gallus gallus	66.00	5.00e-178	617.00
IUUC-Gac-041945	Gasterosteus aculeatus	50.66	5.00e-78	285.00
IUUC-Ggo-044488	Gorilla gorilla	91.54	0.00e+00	959.00
IUUC-Hsa-045909	Homo sapiens	91.38	0.00e+00	958.00
IUUC-Itr-049058	Ictidomys tridecemlineatus	90.81	2.00e-125	441.00
IUUC-Lch-049481	Latimeria chalumnae	55.90	2.00e-154	539.00
IUUC-Loc-052715	Lepisosteus oculatus	52.88	2.00e-143	503.00
IUUC-Laf-053444	Loxodonta africana	88.91	0.00e+00	945.00
IUUC-Mcc-054844	Macaca mulatta	91.38	0.00e+00	927.00
IUUC-Meu-056491	Macropus eugenii	66.94	0.00e+00	633.00
IUUC-Mga-060154	Meleagris gallopavo	65.64	1.00e-176	612.00
IUUC-Mmr-061099	Microcebus murinus	91.07	0.00e+00	928.00
IUUC-Mdo-062769	Monodelphis domestica	72.69	0.00e+00	776.00
IUUC-Mmu-063136	Mus musculus	86.83	0.00e+00	820.00
IUUC-Mpu-066509	Mustela putorius furo	94.76	0.00e+00	946.00
IUUC-Mlu-067174	Myotis lucifugus	88.59	0.00e+00	911.00
IUUC-Nle-070147	Nomascus leucogenys	91.38	0.00e+00	963.00
IUUC-Opr-070752	Ochotona princeps	82.97	3.00e-171	595.00
IUUC-Ont-071810	Oreochromis niloticus	54.34	8.00e-101	361.00
IUUC-Oan-072731	Ornithorhynchus anatinus	73.87	4.00e-169	587.00
IUUC-Ocu-074331	Oryctolagus cuniculus	90.64	0.00e+00	918.00
IUUC-Ola-086404	Oryzias latipes	46.03	1.00e-89	323.00
IUUC-Oga-088200	Otolemur garnettii	91.07	0.00e+00	1010.00
IUUC-Oar-090423	Ovis aries	85.05	0.00e+00	843.00
IUUC-Ptr-091230	Pan troglodytes	91.69	0.00e+00	964.00
IUUC-Pan-091823	Papio anubis	91.22	0.00e+00	926.00
IUUC-Psi-093127	Pelodiscus sinensis	64.69	6.00e-168	583.00
IUUC-Pfo-096539	Poecilia formosa	48.97	2.00e-87	317.00
IUUC-Pab-097666	Pongo abelii	91.85	0.00e+00	954.00
IUUC-Pca-100812	Procavia capensis	84.07	2.00e-136	479.00
IUUC-Pva-102260	Pteropus vampyrus	84.76	0.00e+00	795.00
IUUC-Rno-106038	Rattus norvegicus	86.05	0.00e+00	852.00
IUUC-Sha-106975	Sarcophilus harrisii	73.81	0.00e+00	743.00
IUUC-Sar-113386	Sorex araneus	86.99	2.00e-108	386.00
IUUC-Ssc-115569	Sus scrofa	92.68	4.00e-116	410.00
IUUC-Tgu-117104	Taeniopygia guttata	64.72	0.00e+00	627.00
IUUC-Tru-117649	Takifugu rubripes	50.26	7.00e-95	341.00
IUUC-Tsy-119258	Tarsius syrichta	82.45	0.00e+00	845.00
IUUC-Tni-120755	Tetraodon nigroviridis	45.66	5.00e-125	441.00
IUUC-Tbe-127842	Tupaia belangeri	72.06	0.00e+00	674.00
IUUC-Ttr-129205	Tursiops truncatus	90.24	0.00e+00	836.00
IUUC-Vpa-130434	Vicugna pacos	86.30	0.00e+00	782.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence