iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/F-box	F-box	11069107

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	3.70e-05	23.8	134	192

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 85   apapaptptpeegpdaglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
            pa   +p p eg   +++++l  e+l +i+++l+ ++l+raa+vc  w+ +a  k++wk v
   Q: 134  RPASPESPPPVEG---THISNLFPELLEQIFEHLPVRDLGRAAQVCTAWRDAAYAKSVWKGV 192
           3555555666665...46889999**************************99998****976 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MATNTELLPF HHQTIAVLNN LNSHCGGSGS NGAATSGGAA IGGAGAGGAP SWAMDELYQQ 60
TELPGLTRTG ATTTHHHLLR FTPYALHHRP PHHQLQTLPP ALYLQHAAAA AAAAAAAAAH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCTGCGA GTTCAGTTTT TCTTTATCAT CCGGTTCGTG CACATCGCGT CTCGGCCGCA 60
AGAACAAAGA ACACACAAAT AGAACTTGGA CTTCCAACTA CACACAGTGC TCGAGTTAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000881	Aegilops tauschii	26.72	3.00e-23	103.00
IUUC-Aml-002246	Ailuropoda melanoleuca	63.24	4.00e-142	496.00
IUUC-Apl-003553	Anas platyrhynchos	60.90	2.00e-92	331.00
IUUC-Aca-004590	Anolis carolinensis	55.68	2.00e-56	210.00
IUUC-Ame-011944	Astyanax mexicanus	63.50	9.00e-146	508.00
IUUC-Bta-012544	Bos taurus	63.24	4.00e-142	496.00
IUUC-Bci-013923	Botrytis cinerea	27.46	5.00e-23	102.00
IUUC-Bdi-014086	Brachypodium distachyon	30.22	9.00e-27	114.00
IUUC-Bol-016495	Brassica oleracea	29.71	3.00e-29	122.00
IUUC-Bra-017778	Brassica rapa	27.30	1.00e-26	113.00
IUUC-Cja-019913	Callithrix jacchus	63.24	5.00e-142	496.00
IUUC-Cfa-020197	Canis familiaris	60.40	3.00e-103	367.00
IUUC-Cpo-022294	Cavia porcellus	61.10	4.00e-134	470.00
IUUC-Csa-023181	Chlorocebus sabaeus	62.66	1.00e-138	485.00
IUUC-Cme-027296	Cyanidioschyzon merolae	25.54	3.00e-15	77.80
IUUC-Dre-028033	Danio rerio	64.27	1.00e-147	514.00
IUUC-Dno-029787	Dasypus novemcinctus	63.24	4.00e-142	496.00
IUUC-Ete-032977	Echinops telfairi	63.24	5.00e-142	496.00
IUUC-Eca-033691	Equus caballus	59.75	2.00e-127	448.00
IUUC-Fca-035767	Felis catus	63.02	4.00e-140	489.00
IUUC-Fal-037251	Ficedula albicollis	63.24	1.00e-135	475.00
IUUC-Gmo-039594	Gadus morhua	62.98	8.00e-145	505.00
IUUC-Gga-040176	Gallus gallus	63.24	8.00e-136	475.00
IUUC-Gac-041451	Gasterosteus aculeatus	63.50	4.00e-146	510.00
IUUC-Ggo-044920	Gorilla gorilla	61.01	3.00e-95	340.00
IUUC-Hsa-046454	Homo sapiens	63.24	4.00e-142	496.00
IUUC-Hvu-047491	Hordeum vulgare	31.27	6.00e-27	114.00
IUUC-Itr-048932	Ictidomys tridecemlineatus	60.36	1.00e-115	408.00
IUUC-Kpa-049189	Komagataella pastoris	27.09	5.00e-19	89.40
IUUC-Lch-050647	Latimeria chalumnae	64.78	9.00e-148	515.00
IUUC-Lpe-051447	Leersia perrieri	29.21	2.00e-29	122.00
IUUC-Loc-051978	Lepisosteus oculatus	64.01	5.00e-147	513.00
IUUC-Lma-053322	Leptosphaeria maculans	26.18	8.00e-21	95.50
IUUC-Mcc-055878	Macaca mulatta	63.24	4.00e-142	496.00
IUUC-Meu-056536	Macropus eugenii	62.60	2.00e-133	468.00
IUUC-Mmr-061440	Microcebus murinus	63.24	7.00e-142	496.00
IUUC-Mdo-062821	Monodelphis domestica	63.24	4.00e-142	496.00
IUUC-Mmu-063826	Mus musculus	63.24	4.00e-142	496.00
IUUC-Mpu-066312	Mustela putorius furo	63.24	4.00e-142	496.00
IUUC-Mlu-067341	Myotis lucifugus	63.24	3.00e-142	497.00
IUUC-Nle-069771	Nomascus leucogenys	63.24	4.00e-142	496.00
IUUC-Ont-072668	Oreochromis niloticus	63.75	5.00e-146	509.00
IUUC-Ocu-073972	Oryctolagus cuniculus	63.24	1.00e-141	495.00
IUUC-Oba-075770	Oryza barthii	29.21	2.00e-29	123.00
IUUC-Obr-076309	Oryza brachyantha	30.14	4.00e-28	118.00
IUUC-Ogl-077750	Oryza glaberrima	29.21	2.00e-29	122.00
IUUC-Ogu-078348	Oryza glumaepatula	29.55	2.00e-29	123.00
IUUC-Oin-079425	Oryza indica	29.55	2.00e-29	123.00
IUUC-Ome-082010	Oryza meridionalis	29.90	1.00e-29	124.00
IUUC-Oni-083116	Oryza nivara	29.21	7.00e-29	120.00
IUUC-Opu-083924	Oryza punctata	29.90	2.00e-29	123.00
IUUC-Oru-084612	Oryza rufipogon	29.21	8.00e-29	121.00
IUUC-Osa-085630	Oryza sativa	29.21	2.00e-29	123.00
IUUC-Ola-087359	Oryzias latipes	63.75	3.00e-146	510.00
IUUC-Oga-088437	Otolemur garnettii	63.24	4.00e-142	496.00
IUUC-Ptr-091419	Pan troglodytes	62.13	3.00e-134	470.00
IUUC-Pan-091932	Papio anubis	63.24	3.00e-142	497.00
IUUC-Psi-093623	Pelodiscus sinensis	60.41	1.00e-93	335.00
IUUC-Pma-094244	Petromyzon marinus	57.99	1.00e-105	375.00
IUUC-Pfo-097490	Poecilia formosa	63.75	5.00e-146	509.00
IUUC-Pab-098368	Pongo abelii	63.24	4.00e-142	496.00
IUUC-Pca-100216	Procavia capensis	62.22	5.00e-94	336.00
IUUC-Pte-104075	Pyrenophora teres	27.30	8.00e-20	92.00
IUUC-Pyt-104822	Pyrenophora triticirepentis	27.05	1.00e-19	91.30
IUUC-Sha-107456	Sarcophilus harrisii	58.88	8.00e-106	375.00
IUUC-Sja-107860	Schizosaccharomyces japonicus	25.44	1.00e-24	107.00
IUUC-Spo-108376	Schizosaccharomyces pombe	25.06	4.00e-14	71.60
IUUC-Ssl-108575	Sclerotinia sclerotiorum	28.63	1.00e-17	84.70
IUUC-Sit-110068	Setaria italica	30.85	5.00e-30	125.00
IUUC-Tru-117892	Takifugu rubripes	63.75	5.00e-146	509.00
IUUC-Tae-124451	Triticum aestivum	30.12	1.00e-27	117.00
IUUC-Tur-126305	Triticum urartu	29.94	8.00e-28	117.00
IUUC-Vpa-130165	Vicugna pacos	59.86	1.00e-97	348.00
IUUC-Xtr-132620	Xenopus tropicalis	62.98	4.00e-142	496.00
IUUC-Xma-133916	Xiphophorus maculatus	63.75	5.00e-146	509.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence