iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC	RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.80e-12	47.4	1060	1112

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlvi.ekeeqdegWlkgvkelegkrGlfPen 57
            ++ +l+dy++q+ddeL lk+Gd + v+  ++e + +W+ +   l+ k+G +P n
   Q: 1060 GVIYALWDYQPQHDDELLLKEGDCMAVVrREDEDETEWWWA--RLNDKEGYVPRN 1112
           56789***********************98999999***99..9*********99 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MRFGSKMMPM FLTVYLSNSE QHFTEVPVTP ETVCRDVVDL CKEPGESDCH LAEVWCGSER 60
PVADNERMFD VLQRFGSQRN EVRFFLRHER PPNRDIVSGP RSQDAGVKRN GVKVPGEHRR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCTCGTTCT CGCTCCGCTT CCCCGGGCCC GCGACCCCCG GGCCACTTCT GCTCCGCCAG 60
GCCGCGGCCA GACCCCCGCT TCCATGCGGT TCGGGTCCAA AATGATGCCG GTAAGCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001452--SH3_domain
IPR029071--Ubiquitin-rel_dom

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50002--SH3

Pfam

PF12796--Ank_2
PF00018--SH3_1

SMART

SM00248--ANK
SM00326--SH3

Gene Ontology

GO:0005634--C:nucleus
GO:0048471--C:perinuclear region of cytoplasm
GO:0072332--P:intrinsic apoptotic signaling pathway by p53 class mediator
GO:1900119--P:positive regulation of execution phase of apoptosis
GO:1901216--P:positive regulation of neuron death

KEGG

rno:305025

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001474	Ailuropoda melanoleuca	84.34	0.00e+00	1692.00
IUUC-Apl-003477	Anas platyrhynchos	77.50	0.00e+00	1480.00
IUUC-Aca-005300	Anolis carolinensis	75.52	0.00e+00	1514.00
IUUC-Bta-013530	Bos taurus	86.42	0.00e+00	1696.00
IUUC-Cja-019881	Callithrix jacchus	90.35	1.00e-175	608.00
IUUC-Cfa-021199	Canis familiaris	84.90	0.00e+00	1683.00
IUUC-Cpo-021960	Cavia porcellus	81.00	0.00e+00	1583.00
IUUC-Csa-023763	Chlorocebus sabaeus	88.99	0.00e+00	1872.00
IUUC-Cho-025060	Choloepus hoffmanni	79.04	0.00e+00	906.00
IUUC-Dno-029432	Dasypus novemcinctus	84.13	0.00e+00	1619.00
IUUC-Dor-030603	Dipodomys ordii	84.97	0.00e+00	1106.00
IUUC-Ete-032395	Echinops telfairi	69.25	0.00e+00	756.00
IUUC-Eca-034204	Equus caballus	85.79	0.00e+00	1739.00
IUUC-Eeu-035021	Erinaceus europaeus	73.81	6.00e-171	595.00
IUUC-Fca-035718	Felis catus	77.91	0.00e+00	1507.00
IUUC-Fal-037272	Ficedula albicollis	75.87	0.00e+00	1430.00
IUUC-Gga-040793	Gallus gallus	77.44	0.00e+00	1335.00
IUUC-Ggo-045018	Gorilla gorilla	89.06	0.00e+00	1875.00
IUUC-Hsa-046425	Homo sapiens	88.90	0.00e+00	1842.00
IUUC-Itr-048708	Ictidomys tridecemlineatus	88.93	0.00e+00	1842.00
IUUC-Lch-050430	Latimeria chalumnae	67.83	0.00e+00	1311.00
IUUC-Loc-052603	Lepisosteus oculatus	57.31	1.00e-180	627.00
IUUC-Laf-054080	Loxodonta africana	85.28	0.00e+00	1781.00
IUUC-Mcc-055676	Macaca mulatta	88.99	0.00e+00	1869.00
IUUC-Meu-056686	Macropus eugenii	75.11	0.00e+00	862.00
IUUC-Mga-059342	Meleagris gallopavo	77.58	0.00e+00	1554.00
IUUC-Mmr-061245	Microcebus murinus	87.37	0.00e+00	1776.00
IUUC-Mdo-063015	Monodelphis domestica	81.63	0.00e+00	1682.00
IUUC-Mmu-063141	Mus musculus	94.71	0.00e+00	1943.00
IUUC-Mpu-065986	Mustela putorius furo	84.52	0.00e+00	1616.00
IUUC-Mlu-067869	Myotis lucifugus	84.13	0.00e+00	1697.00
IUUC-Nle-069765	Nomascus leucogenys	89.07	0.00e+00	1840.00
IUUC-Opr-070648	Ochotona princeps	84.01	0.00e+00	1699.00
IUUC-Oan-073404	Ornithorhynchus anatinus	79.93	0.00e+00	1605.00
IUUC-Ocu-074540	Oryctolagus cuniculus	87.75	0.00e+00	1738.00
IUUC-Oga-088550	Otolemur garnettii	87.38	0.00e+00	1771.00
IUUC-Oar-090212	Ovis aries	84.99	0.00e+00	1662.00
IUUC-Ptr-091623	Pan troglodytes	88.88	0.00e+00	1835.00
IUUC-Psi-093092	Pelodiscus sinensis	75.84	0.00e+00	1531.00
IUUC-Pab-098154	Pongo abelii	89.16	0.00e+00	1838.00
IUUC-Pca-100620	Procavia capensis	93.03	8.00e-158	551.00
IUUC-Pva-103003	Pteropus vampyrus	81.62	0.00e+00	1149.00
IUUC-Sha-106806	Sarcophilus harrisii	81.34	0.00e+00	1632.00
IUUC-Sar-113225	Sorex araneus	83.33	0.00e+00	1704.00
IUUC-Ssc-115981	Sus scrofa	86.42	0.00e+00	1680.00
IUUC-Tgu-116747	Taeniopygia guttata	71.96	0.00e+00	959.00
IUUC-Tsy-119114	Tarsius syrichta	84.20	0.00e+00	1756.00
IUUC-Ttr-128278	Tursiops truncatus	84.03	0.00e+00	1678.00
IUUC-Vpa-130152	Vicugna pacos	83.94	0.00e+00	758.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence