iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044411

UUCD1 version

UUC-GoG-00846

Ensembl Protein ID

ENSGGOP00000022993.1

UniProt Accession

G3S4J1; G3S4J1_GORGO

Protein Name

Uncharacterized protein

Gene Name

TRIM62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000013967.2	ENSGGOT00000027387.1	ENSGGOP00000022993.1
ENSGGOG00000013967.2	ENSGGOT00000014017.2	ENSGGOP00000013625.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.80e-08	34.5	11	54
E3 activity/RING/U-box	9.80e-07	29.2	6	75

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCl+ ++d p++l+C H f++ C+ ++w+ +   ++++  CP Cr
   Q: 11   CSICLSIYQD-PVSLGCEHYFCRRCItEHWVRQE--AQGARDCPECR 54
           **********.*******************5555..**********8 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwl....asggktcPvtrqplteedlvPnltlrrliqaw 68
            +e+lC+I l + +dPv l + + + r++I ++     a+g + cP +r++++e  l P+l l ++++++
   Q: 6    KDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWvrqeAQGARDCPECRRTFAEPALAPSLKLANIVERY 75
           689***************************9888455444444*******************99999887 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MACSLKDELL CSICLSIYQD PVSLGCEHYF CRRCITEHWV RQEAQGARDC PECRRTFAEP 60
ALAPSLKLAN IVERYSAFPL DAILNARRAA RPCQAHDKVK LFCLTDRALL CFFCDEPALH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGTGCA GCCTCAAGGA CGAGCTGCTG TGCTCCATCT GCCTGAGCAT CTACCAGGAC 60
CCGGTGAGCC TGGGCTGCGA GCACTACTTC TGCCGCCGCT GCATCACCGA GCACTGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0010719--P:negative regulation of epithelial to mesenchymal transition
GO:0032897--P:negative regulation of viral transcription
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0046596--P:regulation of viral entry into host cell
GO:1902186--P:regulation of viral release from host cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002199	Ailuropoda melanoleuca	93.08	0.00e+00	868.00
IUUC-Apl-003767	Anas platyrhynchos	81.12	0.00e+00	723.00
IUUC-Aca-004412	Anolis carolinensis	77.92	0.00e+00	736.00
IUUC-Ame-010927	Astyanax mexicanus	76.73	0.00e+00	769.00
IUUC-Bta-012927	Bos taurus	92.87	0.00e+00	867.00
IUUC-Cja-019317	Callithrix jacchus	86.58	0.00e+00	779.00
IUUC-Cfa-020292	Canis familiaris	90.35	8.00e-177	612.00
IUUC-Cpo-022274	Cavia porcellus	90.38	2.00e-178	618.00
IUUC-Csa-023042	Chlorocebus sabaeus	93.08	0.00e+00	868.00
IUUC-Dre-028493	Danio rerio	75.68	0.00e+00	765.00
IUUC-Dno-030029	Dasypus novemcinctus	88.68	0.00e+00	808.00
IUUC-Dor-031051	Dipodomys ordii	90.15	0.00e+00	818.00
IUUC-Ete-032752	Echinops telfairi	98.32	4.00e-107	381.00
IUUC-Eca-033898	Equus caballus	73.47	0.00e+00	739.00
IUUC-Eeu-034659	Erinaceus europaeus	83.44	1.00e-61	229.00
IUUC-Fca-035492	Felis catus	84.73	0.00e+00	801.00
IUUC-Fal-036867	Ficedula albicollis	81.40	0.00e+00	778.00
IUUC-Gmo-038916	Gadus morhua	76.10	0.00e+00	739.00
IUUC-Gga-040360	Gallus gallus	83.86	0.00e+00	794.00
IUUC-Gac-041871	Gasterosteus aculeatus	76.73	0.00e+00	773.00
IUUC-Hsa-047025	Homo sapiens	92.87	0.00e+00	900.00
IUUC-Itr-047905	Ictidomys tridecemlineatus	93.08	0.00e+00	868.00
IUUC-Loc-052114	Lepisosteus oculatus	78.83	0.00e+00	786.00
IUUC-Laf-054359	Loxodonta africana	85.49	1.00e-169	588.00
IUUC-Mcc-055563	Macaca mulatta	93.08	0.00e+00	868.00
IUUC-Meu-056027	Macropus eugenii	75.68	0.00e+00	716.00
IUUC-Mga-060146	Meleagris gallopavo	83.72	4.00e-75	273.00
IUUC-Mmr-060822	Microcebus murinus	92.87	0.00e+00	866.00
IUUC-Mdo-062117	Monodelphis domestica	70.95	5.00e-160	557.00
IUUC-Mmu-064086	Mus musculus	92.87	0.00e+00	867.00
IUUC-Mpu-066378	Mustela putorius furo	93.08	0.00e+00	868.00
IUUC-Mlu-067155	Myotis lucifugus	91.95	0.00e+00	880.00
IUUC-Nle-069464	Nomascus leucogenys	92.66	0.00e+00	866.00
IUUC-Opr-071058	Ochotona princeps	85.20	9.00e-109	387.00
IUUC-Ont-071253	Oreochromis niloticus	71.70	0.00e+00	686.00
IUUC-Oan-073614	Ornithorhynchus anatinus	93.67	1.00e-94	337.00
IUUC-Ola-086794	Oryzias latipes	77.15	0.00e+00	769.00
IUUC-Oga-088889	Otolemur garnettii	92.45	0.00e+00	865.00
IUUC-Oar-089203	Ovis aries	88.58	0.00e+00	757.00
IUUC-Ptr-090795	Pan troglodytes	93.08	0.00e+00	900.00
IUUC-Pfo-096942	Poecilia formosa	76.31	0.00e+00	761.00
IUUC-Pab-097936	Pongo abelii	78.07	6.00e-157	546.00
IUUC-Pca-100397	Procavia capensis	91.61	0.00e+00	857.00
IUUC-Ppe-101916	Prunus persica	30.97	3.00e-10	61.20
IUUC-Pva-102293	Pteropus vampyrus	90.03	1.00e-173	602.00
IUUC-Rno-105551	Rattus norvegicus	93.08	0.00e+00	868.00
IUUC-Ssc-115983	Sus scrofa	93.08	0.00e+00	868.00
IUUC-Tgu-117279	Taeniopygia guttata	68.07	1.00e-164	572.00
IUUC-Tru-118238	Takifugu rubripes	76.52	0.00e+00	767.00
IUUC-Tni-119788	Tetraodon nigroviridis	61.00	3.00e-160	558.00
IUUC-Uma-129518	Ustilago maydis	45.83	4.00e-07	50.10
IUUC-Xtr-132768	Xenopus tropicalis	70.99	0.00e+00	707.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence