iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062126

Ensembl Protein ID

ENSMODP00000010286.3

UniProt Accession

F6YIY3; F6YIY3_MONDO

Protein Name

Uncharacterized protein

Gene Name

LATS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000008278.3	ENSMODT00000010485.3	ENSMODP00000010286.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	1.50e-06	28.3	96	133

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l++lv  G+d+e a++aL ++ ++n+eaA+ey+ 
   Q: 96   NRQMLQELVKVGCDQEMAIRALKQTgSKNIEAALEYIS 133
           679*********************************86 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPP KSSGQGLPVG PGSDTSLDTK ILVVKDAARQ 60
QQMKPTPKFG PYQKALREIR YSLLPFANES SAVDVNRQML QELVKVGCDQ EMAIRALKQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATATAGCTCT GCAAAATGAG GACTCTAGAA ATTTTTAGGT TCTCTGTAGG AACTATGAAG 60
ATTGAAGCAA AGAAAAATTA AAAAGGAAAT CATTTTGAAA GTATGTTTAC AATGAACTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0034613--P:cellular protein localization
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0018105--P:peptidyl-serine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0046620--P:regulation of organ growth

KEGG

mdo:100018709

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001960	Ailuropoda melanoleuca	77.52	0.00e+00	1750.00
IUUC-Apl-003521	Anas platyrhynchos	83.13	0.00e+00	1491.00
IUUC-Aca-004995	Anolis carolinensis	77.89	0.00e+00	1744.00
IUUC-Ame-011481	Astyanax mexicanus	62.67	0.00e+00	1281.00
IUUC-Bta-012618	Bos taurus	81.58	0.00e+00	984.00
IUUC-Cja-019430	Callithrix jacchus	74.03	0.00e+00	1630.00
IUUC-Cfa-020687	Canis familiaris	77.01	0.00e+00	1687.00
IUUC-Cpo-021985	Cavia porcellus	83.28	0.00e+00	1068.00
IUUC-Csa-023534	Chlorocebus sabaeus	92.13	0.00e+00	963.00
IUUC-Dre-027538	Danio rerio	62.65	0.00e+00	1288.00
IUUC-Dno-029126	Dasypus novemcinctus	79.82	0.00e+00	1808.00
IUUC-Dor-030172	Dipodomys ordii	71.88	0.00e+00	1399.00
IUUC-Eca-033868	Equus caballus	77.63	0.00e+00	1692.00
IUUC-Eeu-034881	Erinaceus europaeus	60.21	0.00e+00	1229.00
IUUC-Fca-036203	Felis catus	71.69	0.00e+00	1556.00
IUUC-Fal-036668	Ficedula albicollis	83.78	0.00e+00	1912.00
IUUC-Gmo-039195	Gadus morhua	85.51	0.00e+00	788.00
IUUC-Gac-041789	Gasterosteus aculeatus	60.99	0.00e+00	1190.00
IUUC-Ggo-044904	Gorilla gorilla	72.98	0.00e+00	1583.00
IUUC-Hsa-046254	Homo sapiens	75.02	0.00e+00	1598.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	73.39	0.00e+00	1421.00
IUUC-Lch-050079	Latimeria chalumnae	71.97	0.00e+00	1586.00
IUUC-Loc-052265	Lepisosteus oculatus	82.95	0.00e+00	897.00
IUUC-Laf-053806	Loxodonta africana	76.13	0.00e+00	1713.00
IUUC-Mcc-055253	Macaca mulatta	75.38	0.00e+00	1621.00
IUUC-Meu-056509	Macropus eugenii	91.43	0.00e+00	883.00
IUUC-Mga-059600	Meleagris gallopavo	83.16	0.00e+00	1906.00
IUUC-Mmr-061586	Microcebus murinus	74.20	0.00e+00	1563.00
IUUC-Mmu-063164	Mus musculus	69.90	0.00e+00	1461.00
IUUC-Mpu-065992	Mustela putorius furo	77.70	0.00e+00	1745.00
IUUC-Mlu-067728	Myotis lucifugus	70.76	0.00e+00	1524.00
IUUC-Nle-069546	Nomascus leucogenys	75.29	0.00e+00	1595.00
IUUC-Opr-070872	Ochotona princeps	72.06	0.00e+00	1531.00
IUUC-Ont-072296	Oreochromis niloticus	87.42	0.00e+00	926.00
IUUC-Ocu-074068	Oryctolagus cuniculus	73.03	0.00e+00	1565.00
IUUC-Ola-086756	Oryzias latipes	61.11	0.00e+00	1224.00
IUUC-Oga-089066	Otolemur garnettii	74.67	0.00e+00	1637.00
IUUC-Oar-090416	Ovis aries	81.35	0.00e+00	980.00
IUUC-Ptr-091247	Pan troglodytes	75.29	0.00e+00	1626.00
IUUC-Pan-092438	Papio anubis	75.38	0.00e+00	1620.00
IUUC-Psi-093920	Pelodiscus sinensis	82.21	0.00e+00	1894.00
IUUC-Pfo-096334	Poecilia formosa	61.43	0.00e+00	1229.00
IUUC-Pab-098452	Pongo abelii	74.45	0.00e+00	1612.00
IUUC-Pca-101081	Procavia capensis	71.88	0.00e+00	1588.00
IUUC-Rno-105102	Rattus norvegicus	70.48	0.00e+00	1461.00
IUUC-Sha-106917	Sarcophilus harrisii	93.68	0.00e+00	2125.00
IUUC-Sar-113711	Sorex araneus	69.95	0.00e+00	1429.00
IUUC-Tgu-116553	Taeniopygia guttata	81.46	0.00e+00	1859.00
IUUC-Tru-118069	Takifugu rubripes	59.88	0.00e+00	1216.00
IUUC-Tni-120617	Tetraodon nigroviridis	58.95	0.00e+00	1194.00
IUUC-Ttr-129256	Tursiops truncatus	78.66	0.00e+00	1050.00
IUUC-Xtr-132593	Xenopus tropicalis	72.13	0.00e+00	1560.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence