iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/MINDY	1.10e-65	219.7	249	371

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/MINDY

   S: 1    nilllswkvklvpkkevitleelievlgdilldvkdkekseiselnyeqnvddalsllpklaeGldvnvrftGvrsfeytkecsvfdll 89
           n+lll+wkvkl+p++e+it+e+l+e+lgd++l++k+ke+sei+++nyeqn++da+++l+kl++GldvnvrftGvr+feyt+ec+vfdll
   Q: 249  NVLLLAWKVKLPPMMEIITAEQLMEYLGDYMLEAKPKEISEIQRVNYEQNMSDAMAILHKLQTGLDVNVRFTGVRVFEYTPECIVFDLL 337
           9**************************************************************************************** PP
   S: 90   didlyhGWlvdsqideavkavgklsyeqlveril 123
           di+lyhGWlvd+qid++v+avg++sy+qlve+i+
   Q: 338  DIPLYHGWLVDPQIDDIVRAVGNCSYNQLVEKII 371
           *********************************8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MENGPDSPQP LELGVPAGRV STPEGRRRDG REAEDGPAGR AVDSGGQGAA AARSSLGDPT 60
SPSQHGCSAG SDLKNSASSS PVASEAPSRG QHKVTASPEL AEAAAGRGSG PVGDTGTCRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGCGCGCTC CCGCCGCCCT CTACGGTGAC GTGCCTGGCC GAGGCCGCGC TAGGGCGCTG 60
GAGCTGCTAC AGAGCCGCTG TCATGGCGTC GGAGGCGCTA GCTGAGGAGA GCCGGCCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR007518--MINDY
IPR033979--MINDY_domain

Pfam

PF04424--MINDY_DUB

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0016807--F:cysteine-type carboxypeptidase activity
GO:0071795--F:K11-linked polyubiquitin binding
GO:0036435--F:K48-linked polyubiquitin binding
GO:0071796--F:K6-linked polyubiquitin binding
GO:0070530--F:K63-linked polyubiquitin binding
GO:1990380--F:Lys48-specific deubiquitinase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity

KEGG

rno:363089

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-136382	Ailuropoda melanoleuca	67.83	1.00e-146	513.00
IUUC-Apl-136387	Anas platyrhynchos	94.62	2.00e-151	528.00
IUUC-Aca-136392	Anolis carolinensis	91.88	3.00e-166	578.00
IUUC-Acl-136400	Aspergillus clavatus	30.09	9.00e-27	115.00
IUUC-Afl-136401	Aspergillus flavus	40.74	4.00e-11	63.90
IUUC-Ate-136406	Aspergillus terreus	30.13	1.00e-23	105.00
IUUC-Bta-136414	Bos taurus	73.66	0.00e+00	689.00
IUUC-Cja-136427	Callithrix jacchus	97.58	0.00e+00	640.00
IUUC-Cfa-136430	Canis familiaris	95.34	0.00e+00	634.00
IUUC-Cpo-136434	Cavia porcellus	85.71	1.00e-178	619.00
IUUC-Csa-136441	Chlorocebus sabaeus	78.67	0.00e+00	768.00
IUUC-Cho-136445	Choloepus hoffmanni	76.84	3.00e-74	271.00
IUUC-Csv-136449	Ciona savignyi	55.69	5.00e-79	287.00
IUUC-Cgl-136450	Colletotrichum gloeosporioides	29.51	4.00e-25	110.00
IUUC-Dre-136454	Danio rerio	81.19	7.00e-178	617.00
IUUC-Dno-136459	Dasypus novemcinctus	77.96	0.00e+00	667.00
IUUC-Dor-136463	Dipodomys ordii	74.91	1.00e-106	380.00
IUUC-Ete-136469	Echinops telfairi	90.09	3.00e-155	541.00
IUUC-Eca-136473	Equus caballus	93.60	0.00e+00	626.00
IUUC-Fca-136479	Felis catus	94.54	0.00e+00	640.00
IUUC-Fal-136483	Ficedula albicollis	94.22	6.00e-150	523.00
IUUC-Fox-136484	Fusarium oxysporum	29.56	1.00e-25	111.00
IUUC-Fso-136485	Fusarium solani	28.57	4.00e-28	120.00
IUUC-Gmo-136489	Gadus morhua	77.49	2.00e-171	595.00
IUUC-Ggr-136490	Gaeumannomyces graminis	25.70	2.00e-23	105.00
IUUC-Gga-136493	Gallus gallus	85.75	0.00e+00	629.00
IUUC-Gac-136497	Gasterosteus aculeatus	81.84	3.00e-172	597.00
IUUC-Ggo-136505	Gorilla gorilla	76.92	0.00e+00	674.00
IUUC-Hsa-136507	Homo sapiens	80.43	0.00e+00	760.00
IUUC-Lch-136517	Latimeria chalumnae	84.64	4.00e-176	611.00
IUUC-Lpe-136520	Leersia perrieri	34.65	3.00e-31	130.00
IUUC-Loc-136524	Lepisosteus oculatus	84.50	0.00e+00	637.00
IUUC-Lma-136525	Leptosphaeria maculans	31.69	1.00e-31	131.00
IUUC-Laf-136528	Loxodonta africana	96.47	6.00e-172	596.00
IUUC-Mcc-136532	Macaca mulatta	73.24	3.00e-138	484.00
IUUC-Mpo-136538	Magnaporthe poae	26.15	4.00e-22	100.00
IUUC-Mga-136545	Meleagris gallopavo	94.22	2.00e-176	611.00
IUUC-Mmr-136549	Microcebus murinus	93.63	0.00e+00	667.00
IUUC-Mdo-136553	Monodelphis domestica	77.35	0.00e+00	671.00
IUUC-Mmu-136558	Mus musculus	95.51	0.00e+00	821.00
IUUC-Mpu-136563	Mustela putorius furo	84.73	1.00e-154	540.00
IUUC-Mlu-136568	Myotis lucifugus	79.96	0.00e+00	665.00
IUUC-Ncr-136571	Neurospora crassa	28.99	1.00e-25	112.00
IUUC-Nle-136575	Nomascus leucogenys	79.53	0.00e+00	749.00
IUUC-Oan-136584	Ornithorhynchus anatinus	90.67	2.00e-108	384.00
IUUC-Ocu-136588	Oryctolagus cuniculus	83.90	0.00e+00	689.00
IUUC-Ola-136611	Oryzias latipes	78.26	4.00e-168	584.00
IUUC-Olu-136613	Ostreococcus lucimarinus	48.91	2.00e-20	93.20
IUUC-Oga-136616	Otolemur garnettii	78.23	0.00e+00	631.00
IUUC-Oar-136622	Ovis aries	80.84	0.00e+00	684.00
IUUC-Ptr-136626	Pan troglodytes	80.97	0.00e+00	757.00
IUUC-Pan-136629	Papio anubis	77.60	0.00e+00	766.00
IUUC-Psi-136633	Pelodiscus sinensis	89.14	0.00e+00	629.00
IUUC-Pma-136636	Petromyzon marinus	58.67	5.00e-137	481.00
IUUC-Pno-136637	Phaeosphaeria nodorum	32.44	7.00e-30	125.00
IUUC-Pfo-136644	Poecilia formosa	81.07	4.00e-175	607.00
IUUC-Pab-136647	Pongo abelii	79.71	0.00e+00	752.00
IUUC-Pca-136655	Procavia capensis	95.68	2.00e-156	545.00
IUUC-Pva-136659	Pteropus vampyrus	63.31	8.00e-160	556.00
IUUC-Pte-136663	Pyrenophora teres	32.18	4.00e-29	123.00
IUUC-Pyt-136664	Pyrenophora triticirepentis	31.86	8.00e-29	122.00
IUUC-Sce-136670	Saccharomyces cerevisiae	33.09	7.00e-28	117.00
IUUC-Sha-136674	Sarcophilus harrisii	93.51	8.00e-144	502.00
IUUC-Tgu-136696	Taeniopygia guttata	85.42	0.00e+00	632.00
IUUC-Tru-136700	Takifugu rubripes	81.57	5.00e-174	603.00
IUUC-Tsy-136704	Tarsius syrichta	93.92	0.00e+00	649.00
IUUC-Tni-136709	Tetraodon nigroviridis	79.46	9.00e-172	596.00
IUUC-Tre-136712	Trichoderma reesei	33.57	3.00e-26	112.00
IUUC-Tvi-136713	Trichoderma virens	29.68	2.00e-27	117.00
IUUC-Tbe-136721	Tupaia belangeri	91.33	2.00e-157	548.00
IUUC-Ttr-136724	Tursiops truncatus	73.35	0.00e+00	677.00
IUUC-Vda-136728	Verticillium dahliae	31.05	2.00e-25	111.00
IUUC-Vpa-136731	Vicugna pacos	93.70	0.00e+00	630.00
IUUC-Xtr-136736	Xenopus tropicalis	78.68	2.00e-173	602.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence