iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006680

UUCD1 version

UUC-ArT-01512

Ensembl Protein ID

AT1G57800.2

UniProt Accession

Q9FVS2; ORTH3_ARATH

Genbank Protein ID

AAG29230.1; AEE33468.1

Protein Name

E3 ubiquitin-protein ligase ORTHRUS 3; Protein VARIANT IN METHYLATION 5; RING-type E3 ubiquitin transferase ORTHRUS 3

Genbank Nucleotide ID

AC079732; CP002684

Gene Name

ORTH3; VIM5; At1g57800; F12K22.15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G57800	AT1G57800.1	AT1G57800.1
AT1G57800	AT1G57800.2	AT1G57800.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	18643997

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	9.30e-09	36.6	141	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplv.................lpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++C+++++++ ++                 +pCgH  +++C+ kw     + +++ +C +Cr
   Q: 141  CSFCMQSLQKP-VSvrvlfalalmlvwflesTPCGHNACLKCFLKW-----MGQGHRSCGTCR 197
           9*******995.5224455555666666666***************.....8**********8 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-protein ligase. May participate in CpG methylation-dependent transcriptional regulation (By similarity).

Protein Sequence
(Fasta)

MTPATQYPCD PEGVCMRCKS MPPPEESLTC GTCVTPWHVS CLLSPPETLS ATLQWLCPDC 60
SGETNPLPVS GVAAGYGSVG SDLVAAIHSI EADETLSAEE KAKKKQQLLS GKGVVDEDDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGCCTG CCACCCAGTA CCCATGCGAC CCCGAAGGTG TATGCATGCG ATGCAAATCG 60
ATGCCTCCAC CGGAGGAATC TCTCACTTGC GGCACGTGCG TCACGCCTTG GCACGTGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015947--PUA-like_domain
IPR003105--SRA_YDG
IPR019786--Zinc_finger_PHD-type_CS
IPR027370--Znf-RING_LisH
IPR018957--Znf_C3HC4_RING-type
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51015--YDG
PS01359--ZF_PHD_1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02182--SAD_SRA
PF00097--zf-C3HC4
PF13445--zf-RING_UBOX

SMART

SM00249--PHD
SM00184--RING
SM00466--SRA

Gene Ontology

GO:0005720--C:nuclear heterochromatin
GO:0005634--C:nucleus
GO:0042393--F:histone binding
GO:0008327--F:methyl-CpG binding
GO:0010428--F:methyl-CpNpG binding
GO:0010429--F:methyl-CpNpN binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0010424--P:DNA methylation on cytosine within a CG sequence
GO:0010216--P:maintenance of DNA methylation
GO:0016567--P:protein ubiquitination
GO:0090308--P:regulation of methylation-dependent chromatin silencing

KEGG

ath:AT1G57800

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006348	Arabidopsis lyrata	80.39	0.00e+00	1063.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence