iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088757

Ensembl Protein ID

ENSOGAP00000015313.2

UniProt Accession

H0XGU6; H0XGU6_OTOGA

Genbank Protein ID

ENSOGAP00000015313

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03057369

Gene Name

KLHL7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000017098.2	ENSOGAT00000017103.2	ENSOGAP00000015313.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.70e-18	66.8	44	110
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.70e-14	51.6	144	174

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+l v++++++ah++vLaa+S++F+ +f++++ esk + +ve+kd +p+  ++l++F Yt +++ n
   Q: 44   CDVVLMVQERKIPAHRVVLAAASHFFNLMFTTNMLESK-SFEVELKDAEPDIIEQLVEFAYTARISVN 110
           9*************************************.*************************9876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +Nclgi  +A+++dcp+Lk  a+dfi++hF+
   Q: 144  SNCLGISVLAECLDCPELKATADDFIHQHFT 174
           8*****************************7 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MAASGVEKSN KKKTEKKLAA REEAKLLAGF MGVMNNMRKQ KTLCDVVLMV QERKIPAHRV 60
VLAAASHFFN LMFTTNMLES KSFEVELKDA EPDIIEQLVE FAYTARISVN SNNVQSLLDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACTGAGAGA GGATGGCAGC CTCCGGGGTG GAGAAGAGCA ACAAGAAGAA AACAGAGAAG 60
AAACTTGCAG CTCGAGAAGA AGCTAAATTG TTGGCGGGTT TCATGGGCGT CATGAATAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030599--KLHL7
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001981	Ailuropoda melanoleuca	99.32	0.00e+00	1173.00
IUUC-Apl-003183	Anas platyrhynchos	98.20	0.00e+00	1157.00
IUUC-Aca-004273	Anolis carolinensis	97.84	0.00e+00	1157.00
IUUC-Ame-011343	Astyanax mexicanus	83.36	0.00e+00	970.00
IUUC-Bta-012785	Bos taurus	99.15	0.00e+00	1170.00
IUUC-Cja-019038	Callithrix jacchus	99.32	0.00e+00	1198.00
IUUC-Cfa-020774	Canis familiaris	99.45	0.00e+00	1144.00
IUUC-Cpo-021716	Cavia porcellus	99.15	0.00e+00	1167.00
IUUC-Csa-023029	Chlorocebus sabaeus	99.49	0.00e+00	1174.00
IUUC-Cho-024947	Choloepus hoffmanni	76.62	0.00e+00	848.00
IUUC-Dre-028014	Danio rerio	83.40	0.00e+00	879.00
IUUC-Dno-029946	Dasypus novemcinctus	99.15	0.00e+00	1172.00
IUUC-Dor-030916	Dipodomys ordii	82.92	1.00e-176	613.00
IUUC-Dse-031294	Dothistroma septosporum	32.95	3.00e-06	44.30
IUUC-Ete-032454	Echinops telfairi	93.69	0.00e+00	637.00
IUUC-Eca-034041	Equus caballus	98.98	0.00e+00	1171.00
IUUC-Eeu-034627	Erinaceus europaeus	98.98	0.00e+00	971.00
IUUC-Fca-035854	Felis catus	99.32	0.00e+00	1173.00
IUUC-Fal-036883	Ficedula albicollis	97.61	0.00e+00	1158.00
IUUC-Gmo-038902	Gadus morhua	78.74	0.00e+00	899.00
IUUC-Gga-040866	Gallus gallus	97.78	0.00e+00	1164.00
IUUC-Gac-041428	Gasterosteus aculeatus	78.32	0.00e+00	941.00
IUUC-Ggo-044846	Gorilla gorilla	93.50	0.00e+00	1079.00
IUUC-Hsa-047034	Homo sapiens	99.49	0.00e+00	1174.00
IUUC-Itr-048807	Ictidomys tridecemlineatus	98.86	6.00e-141	492.00
IUUC-Lch-049815	Latimeria chalumnae	89.84	0.00e+00	1056.00
IUUC-Loc-052232	Lepisosteus oculatus	85.14	0.00e+00	915.00
IUUC-Laf-053520	Loxodonta africana	98.98	0.00e+00	1170.00
IUUC-Mcc-055237	Macaca mulatta	99.32	0.00e+00	1174.00
IUUC-Meu-056095	Macropus eugenii	92.58	3.00e-175	607.00
IUUC-Mga-059927	Meleagris gallopavo	97.78	0.00e+00	1164.00
IUUC-Mvi-060550	Microbotryum violaceum	39.02	7.70e-01	29.60
IUUC-Mmr-060974	Microcebus murinus	98.22	0.00e+00	1154.00
IUUC-Mdo-062729	Monodelphis domestica	91.85	0.00e+00	1115.00
IUUC-Mmu-063841	Mus musculus	97.27	0.00e+00	1155.00
IUUC-Mpu-066524	Mustela putorius furo	96.52	0.00e+00	1162.00
IUUC-Mlu-067215	Myotis lucifugus	99.46	0.00e+00	1171.00
IUUC-Ncr-068856	Neurospora crassa	29.70	2.00e-04	40.00
IUUC-Nle-069341	Nomascus leucogenys	99.49	0.00e+00	1174.00
IUUC-Opr-070269	Ochotona princeps	98.98	0.00e+00	1171.00
IUUC-Ont-071551	Oreochromis niloticus	79.96	0.00e+00	946.00
IUUC-Oan-072718	Ornithorhynchus anatinus	98.91	0.00e+00	1147.00
IUUC-Ocu-074287	Oryctolagus cuniculus	99.49	0.00e+00	1174.00
IUUC-Ola-086718	Oryzias latipes	78.55	0.00e+00	956.00
IUUC-Oar-090309	Ovis aries	99.15	0.00e+00	1170.00
IUUC-Ptr-090509	Pan troglodytes	99.49	0.00e+00	1174.00
IUUC-Pan-092929	Papio anubis	99.49	0.00e+00	1174.00
IUUC-Psi-092941	Pelodiscus sinensis	98.38	0.00e+00	1160.00
IUUC-Pfo-097421	Poecilia formosa	79.57	0.00e+00	933.00
IUUC-Pab-097792	Pongo abelii	99.49	0.00e+00	1174.00
IUUC-Pca-101033	Procavia capensis	89.63	0.00e+00	856.00
IUUC-Pva-102364	Pteropus vampyrus	88.91	0.00e+00	1028.00
IUUC-Rno-105596	Rattus norvegicus	97.44	0.00e+00	1156.00
IUUC-Sha-106815	Sarcophilus harrisii	99.07	0.00e+00	1125.00
IUUC-Smo-109320	Selaginella moellendorffii	26.72	1.00e-15	79.00
IUUC-Sar-113305	Sorex araneus	98.63	0.00e+00	1168.00
IUUC-Ssc-115871	Sus scrofa	95.52	7.00e-168	582.00
IUUC-Tgu-116940	Taeniopygia guttata	97.84	0.00e+00	1153.00
IUUC-Tru-118682	Takifugu rubripes	78.86	0.00e+00	959.00
IUUC-Tsy-118787	Tarsius syrichta	98.95	0.00e+00	801.00
IUUC-Tni-120224	Tetraodon nigroviridis	79.43	0.00e+00	962.00
IUUC-Tbe-127633	Tupaia belangeri	57.05	6.00e-88	317.00
IUUC-Ttr-128500	Tursiops truncatus	95.22	0.00e+00	1156.00
IUUC-Vpa-130512	Vicugna pacos	96.90	0.00e+00	1116.00
IUUC-Xtr-131983	Xenopus tropicalis	96.95	0.00e+00	1148.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence