iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003745

Ensembl Protein ID

ENSAPLP00000005577.1

UniProt Accession

U3IEA5; U3IEA5_ANAPL

Genbank Protein ID

ENSAPLP00000005577

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01092633

Gene Name

CTTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000005914.1	ENSAPLT00000006208.1	ENSAPLP00000005577.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.80e-13	48.6	504	553

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 504  IALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--VCKGRYGLFPANYVE 553
           79***********************..9*********..7************97 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

VVLQMWKATA GHTISVSQDD GADDWETDPD FVNDVSEKEQ RWGAKTVKGS GHQEHINIHQ 60
LRENVFQEHQ NLKEKELETG PKASHGYGGK FGVEQDRMDK SAVGHEYQSK LSKHCSQVDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGTGTTGC AGATGTGGAA GGCTACTGCA GGGCACACCA TTTCTGTCAG TCAGGATGAC 60
GGAGCTGATG ACTGGGAGAC GGATCCTGAT TTTGTGGTAT GGCTTTCAAA TTTCATCCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	83.12	0.00e+00	873.00
IUUC-Aca-004438	Anolis carolinensis	85.51	0.00e+00	927.00
IUUC-Ame-011170	Astyanax mexicanus	49.82	1.00e-116	412.00
IUUC-Bgr-012041	Blumeria graminis	57.89	5.00e-16	79.30
IUUC-Bta-013563	Bos taurus	82.67	0.00e+00	827.00
IUUC-Bci-013690	Botrytis cinerea	58.82	4.00e-12	66.60
IUUC-Cja-019982	Callithrix jacchus	68.52	8.00e-89	320.00
IUUC-Cfa-020718	Canis familiaris	80.72	0.00e+00	861.00
IUUC-Cpo-022303	Cavia porcellus	83.39	0.00e+00	926.00
IUUC-Csa-023431	Chlorocebus sabaeus	84.66	0.00e+00	858.00
IUUC-Cin-025677	Ciona intestinalis	61.60	2.00e-118	419.00
IUUC-Csv-026140	Ciona savignyi	65.33	6.00e-108	384.00
IUUC-Cme-027279	Cyanidioschyzon merolae	32.79	5.40e+00	25.80
IUUC-Dre-028012	Danio rerio	73.95	1.00e-152	532.00
IUUC-Dno-029332	Dasypus novemcinctus	77.76	0.00e+00	733.00
IUUC-Dor-030437	Dipodomys ordii	58.96	2.00e-71	263.00
IUUC-Dme-031931	Drosophila melanogaster	62.61	3.00e-74	272.00
IUUC-Ete-033160	Echinops telfairi	58.70	2.00e-59	222.00
IUUC-Eca-033801	Equus caballus	84.02	0.00e+00	871.00
IUUC-Fca-035633	Felis catus	82.44	0.00e+00	711.00
IUUC-Fal-036775	Ficedula albicollis	94.22	0.00e+00	889.00
IUUC-Fox-037778	Fusarium oxysporum	59.65	1.00e-14	75.10
IUUC-Gmo-038507	Gadus morhua	56.96	2.00e-20	93.20
IUUC-Gga-040568	Gallus gallus	96.23	0.00e+00	936.00
IUUC-Gac-042253	Gasterosteus aculeatus	56.28	1.00e-116	413.00
IUUC-Ggo-044505	Gorilla gorilla	70.28	2.00e-91	329.00
IUUC-Hsa-046818	Homo sapiens	85.20	0.00e+00	862.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	81.01	0.00e+00	796.00
IUUC-Lch-050199	Latimeria chalumnae	74.10	7.00e-152	530.00
IUUC-Loc-052855	Lepisosteus oculatus	76.90	3.00e-157	548.00
IUUC-Lma-053035	Leptosphaeria maculans	59.18	2.00e-12	67.80
IUUC-Laf-053866	Loxodonta africana	84.68	0.00e+00	914.00
IUUC-Mcc-055515	Macaca mulatta	84.48	0.00e+00	856.00
IUUC-Mga-059791	Meleagris gallopavo	90.31	0.00e+00	917.00
IUUC-Mmr-061147	Microcebus murinus	85.38	0.00e+00	812.00
IUUC-Mdo-062660	Monodelphis domestica	61.50	4.00e-177	615.00
IUUC-Mmu-064023	Mus musculus	84.12	0.00e+00	846.00
IUUC-Mpu-065867	Mustela putorius furo	73.37	0.00e+00	746.00
IUUC-Mlu-067704	Myotis lucifugus	77.24	0.00e+00	734.00
IUUC-Nle-069436	Nomascus leucogenys	69.44	2.00e-92	332.00
IUUC-Ont-071873	Oreochromis niloticus	81.34	8.00e-171	593.00
IUUC-Oan-073528	Ornithorhynchus anatinus	86.03	2.00e-168	584.00
IUUC-Ocu-074686	Oryctolagus cuniculus	70.28	2.00e-91	329.00
IUUC-Ola-086894	Oryzias latipes	63.88	1.00e-83	303.00
IUUC-Oga-088028	Otolemur garnettii	84.30	0.00e+00	850.00
IUUC-Oar-090203	Ovis aries	82.35	0.00e+00	759.00
IUUC-Ptr-090461	Pan troglodytes	70.28	2.00e-91	329.00
IUUC-Pan-092594	Papio anubis	80.14	0.00e+00	808.00
IUUC-Psi-093389	Pelodiscus sinensis	90.32	0.00e+00	898.00
IUUC-Pma-094161	Petromyzon marinus	46.85	1.00e-85	310.00
IUUC-Pfo-096269	Poecilia formosa	61.71	1.00e-112	399.00
IUUC-Pab-097913	Pongo abelii	78.84	0.00e+00	766.00
IUUC-Pca-100668	Procavia capensis	70.67	2.00e-88	319.00
IUUC-Pva-102767	Pteropus vampyrus	58.02	3.00e-70	258.00
IUUC-Rno-105489	Rattus norvegicus	83.39	0.00e+00	823.00
IUUC-Sha-107308	Sarcophilus harrisii	72.30	0.00e+00	692.00
IUUC-Sja-107956	Schizosaccharomyces japonicus	53.45	5.00e-14	72.80
IUUC-Sar-113338	Sorex araneus	57.67	3.00e-67	248.00
IUUC-Ssc-116027	Sus scrofa	69.81	7.00e-92	330.00
IUUC-Tgu-117049	Taeniopygia guttata	86.23	0.00e+00	803.00
IUUC-Tru-118718	Takifugu rubripes	75.91	8.00e-161	560.00
IUUC-Tni-120535	Tetraodon nigroviridis	68.44	3.00e-148	518.00
IUUC-Tre-122167	Trichoderma reesei	59.18	1.00e-11	65.10
IUUC-Tvi-122614	Trichoderma virens	59.18	9.00e-12	65.50
IUUC-Vda-129766	Verticillium dahliae	57.89	1.00e-13	71.60
IUUC-Xtr-131797	Xenopus tropicalis	76.75	2.00e-154	538.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence