iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118751

UUCD1 version

UUC-TaR-00408

Ensembl Protein ID

ENSTRUP00000019810.1

UniProt Accession

H2T572; H2T572_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000007952.1	ENSTRUT00000019888.1	ENSTRUP00000019807.1
ENSTRUG00000007952.1	ENSTRUT00000019889.1	ENSTRUP00000019808.1
ENSTRUG00000007952.1	ENSTRUT00000019890.1	ENSTRUP00000019809.1
ENSTRUG00000007952.1	ENSTRUT00000019891.1	ENSTRUP00000019810.1
ENSTRUG00000007952.1	ENSTRUT00000019892.1	ENSTRUP00000019811.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	6.70e-09	37.4	12	56
E3 activity/RING/U-box	5.60e-09	37.2	8	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle f++ p+++pCgH f++ C+   w +  +  ++   CP+C+
   Q: 12   CSICLEVFEN-PVSTPCGHSFCQRCIsSYW-DGGRGGNRVYFCPICK 56
           **********.***************5555.77777888888****6 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk.....tcPvtrqpl.teedlvPnltlrrliqawce 70
           ++f C+I le++++Pv +p+G+++ +++I  + + g+       cP++++++ +  +l  n tl+++ +++ +
   Q: 8    DQFTCSICLEVFENPVSTPCGHSFCQRCISSYWDGGRGgnrvyFCPICKESFrKRPELHINRTLKEITEQFKH 80
           68******************************988777889***********66667899*******999865 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

AGAFLCEDQF TCSICLEVFE NPVSTPCGHS FCQRCISSYW DGGRGGNRVY FCPICKESFR 60
KRPELHINRT LKEITEQFKH IASSGSPEEG GDGGGLGRGL GKDPVSQSHL TLTQRPGPVH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCTCCACGC CTGCTCTTCC CAATGAGGGA GACGTGAGGC TTCATAAAGG TGTGTGTGTG 60
TGTGTGTGTG TGGCTCATCG CCCTCTTTGT GTTTTCAGTA ATGGCGCTGG CTGGAGCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR003613--Ubox_domain
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY
SM00504--Ubox

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0001666--P:response to hypoxia

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011213	Astyanax mexicanus	47.26	3.00e-142	498.00
IUUC-Gac-042042	Gasterosteus aculeatus	58.61	0.00e+00	645.00
IUUC-Mlu-067864	Myotis lucifugus	43.82	2.00e-42	166.00
IUUC-Ont-071329	Oreochromis niloticus	60.17	0.00e+00	683.00
IUUC-Pfo-097223	Poecilia formosa	60.71	3.00e-147	514.00
IUUC-Tni-119658	Tetraodon nigroviridis	74.47	0.00e+00	776.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence