iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013459

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02053753

Gene Name

VHLL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000016101.4	ENSBTAT00000030804.3	ENSBTAP00000030774.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	25.86	1.00e-03	40.40	IUUC-Dme-031988
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	94.27	6.00e-83	303.00	IUUC-Hsa-046547

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Bos taurus

Protein Sequence
(Fasta)

MPRKAGDAEE AEAGAEEASA EDPGAEREME AGRLRPVLRS VNTREPSQVI FCNRSPRVVL 60
PVWLNFDGEP QPYPTLPPGT GRRIHSYRGH LWLFRDAGTS DGLLVNQTEL FVPSLNVDGQ 120

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Nucleotide Sequence
(Fasta)

ATGCCCCGGA AGGCGGGGGA CGCGGAAGAG GCTGAGGCCG GCGCTGAGGA GGCGAGTGCA 60
GAGGACCCCG GCGCCGAGCG GGAGATGGAG GCCGGGCGGC TGCGGCCGGT GCTGCGCTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002714--VHL
IPR024048--VHL_alpha_dom
IPR024053--VHL_beta_dom
IPR022772--VHL_tumour_suppress_b/a_dom

Pfam

PF01847--VHL
PF17211--VHL_C

Gene Ontology

GO:0005929--C:cilium
GO:0031462--C:Cul2-RING ubiquitin ligase complex
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0030891--C:VCB complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0001525--P:angiogenesis
GO:0043534--P:blood vessel endothelial cell migration
GO:0061073--P:ciliary body morphogenesis
GO:0030198--P:extracellular matrix organization
GO:0048069--P:eye pigmentation
GO:0048877--P:homeostasis of number of retina cells
GO:0061072--P:iris morphogenesis
GO:0006582--P:melanin metabolic process
GO:0045602--P:negative regulation of endothelial cell differentiation
GO:0010629--P:negative regulation of gene expression
GO:1902072--P:negative regulation of hypoxia-inducible factor-1alpha signaling pathway
GO:0070244--P:negative regulation of thymocyte apoptotic process
GO:0006607--P:NLS-bearing protein import into nucleus
GO:0003310--P:pancreatic A cell differentiation
GO:0050679--P:positive regulation of epithelial cell proliferation
GO:0010498--P:proteasomal protein catabolic process
GO:0016567--P:protein ubiquitination
GO:2001233--P:regulation of apoptotic signaling pathway
GO:1903827--P:regulation of cellular protein localization
GO:0003309--P:type B pancreatic cell differentiation

KEGG

bta:540957

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002327	Ailuropoda melanoleuca	82.61	2.00e-70	258.00
IUUC-Apl-003580	Anas platyrhynchos	69.51	8.00e-26	107.00
IUUC-Aca-004492	Anolis carolinensis	79.53	1.00e-57	215.00
IUUC-Ang-009806	Aspergillus niger	40.62	6.50e-02	28.50
IUUC-Ame-011818	Astyanax mexicanus	55.24	3.00e-43	168.00
IUUC-Cel-018173	Caenorhabditis elegans	31.82	1.00e-05	42.40
IUUC-Cja-019826	Callithrix jacchus	92.07	5.00e-86	310.00
IUUC-Cfa-021280	Canis familiaris	93.67	7.00e-84	303.00
IUUC-Cpo-022544	Cavia porcellus	93.17	5.00e-85	306.00
IUUC-Cre-022809	Chlamydomonas reinhardtii	40.00	2.00e-08	53.50
IUUC-Csa-023644	Chlorocebus sabaeus	93.63	2.00e-83	301.00
IUUC-Cho-024479	Choloepus hoffmanni	63.36	5.00e-40	155.00
IUUC-Cin-025505	Ciona intestinalis	26.50	1.00e-05	42.40
IUUC-Cme-027232	Cyanidioschyzon merolae	34.78	2.00e-06	45.40
IUUC-Dre-028350	Danio rerio	53.85	2.00e-32	131.00
IUUC-Dno-029207	Dasypus novemcinctus	84.96	3.00e-51	194.00
IUUC-Dor-030912	Dipodomys ordii	65.56	1.00e-49	189.00
IUUC-Dme-031988	Drosophila melanogaster	25.86	4.00e-05	40.80
IUUC-Eca-034007	Equus caballus	97.50	2.00e-18	83.60
IUUC-Fca-036350	Felis catus	93.59	2.00e-81	294.00
IUUC-Fal-037192	Ficedula albicollis	67.90	6.00e-57	212.00
IUUC-Gmo-038921	Gadus morhua	58.39	9.00e-45	172.00
IUUC-Gga-041016	Gallus gallus	70.42	2.00e-54	204.00
IUUC-Gac-042560	Gasterosteus aculeatus	51.05	6.00e-36	143.00
IUUC-Ggo-045419	Gorilla gorilla	94.19	5.00e-82	296.00
IUUC-Hsa-046547	Homo sapiens	94.19	6.00e-82	296.00
IUUC-Itr-048225	Ictidomys tridecemlineatus	94.97	2.00e-86	310.00
IUUC-Lch-050463	Latimeria chalumnae	63.64	3.00e-54	204.00
IUUC-Loc-052053	Lepisosteus oculatus	58.74	4.00e-48	183.00
IUUC-Laf-053893	Loxodonta africana	92.07	4.00e-86	310.00
IUUC-Mcc-055347	Macaca mulatta	75.35	1.00e-55	208.00
IUUC-Mtr-058490	Medicago truncatula	48.48	6.00e-03	34.30
IUUC-Mdo-062169	Monodelphis domestica	74.47	5.00e-38	148.00
IUUC-Mmu-064366	Mus musculus	92.81	2.00e-73	267.00
IUUC-Mpu-066593	Mustela putorius furo	90.48	2.00e-86	311.00
IUUC-Mlu-066926	Myotis lucifugus	93.12	6.00e-85	306.00
IUUC-Nle-069724	Nomascus leucogenys	94.84	6.00e-83	300.00
IUUC-Opr-070679	Ochotona princeps	82.61	3.00e-75	273.00
IUUC-Ont-071332	Oreochromis niloticus	54.55	9.00e-42	162.00
IUUC-Ola-086869	Oryzias latipes	52.78	4.00e-39	153.00
IUUC-Oga-089124	Otolemur garnettii	92.12	6.00e-85	306.00
IUUC-Oar-089799	Ovis aries	97.00	6.00e-54	201.00
IUUC-Ptr-091186	Pan troglodytes	92.00	6.00e-49	185.00
IUUC-Pan-092150	Papio anubis	94.08	1.00e-81	295.00
IUUC-Psi-094039	Pelodiscus sinensis	68.57	3.00e-52	197.00
IUUC-Pma-094129	Petromyzon marinus	45.45	7.00e-29	120.00
IUUC-Pfo-096892	Poecilia formosa	48.41	5.00e-37	146.00
IUUC-Pab-097822	Pongo abelii	94.84	5.00e-83	300.00
IUUC-Pca-101058	Procavia capensis	86.96	2.00e-75	275.00
IUUC-Pva-102932	Pteropus vampyrus	94.97	9.00e-86	309.00
IUUC-Rno-105050	Rattus norvegicus	88.89	4.00e-86	310.00
IUUC-Sha-106738	Sarcophilus harrisii	81.25	4.00e-43	165.00
IUUC-Ssc-115973	Sus scrofa	91.07	2.00e-88	318.00
IUUC-Tgu-116663	Taeniopygia guttata	71.13	4.00e-34	135.00
IUUC-Tru-118654	Takifugu rubripes	56.64	6.00e-43	166.00
IUUC-Tca-121306	Theobroma cacao	38.89	2.50e-02	30.40
IUUC-Ttr-128418	Tursiops truncatus	93.90	4.00e-88	317.00
IUUC-Vpa-130268	Vicugna pacos	89.32	4.00e-49	187.00
IUUC-Xtr-132506	Xenopus tropicalis	64.00	4.00e-55	206.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence