iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000000796.8	ENSRNOT00000071386.3	ENSRNOP00000063941.1
ENSRNOG00000000796.8	ENSRNOT00000001044.6	ENSRNOP00000001044.5

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	3.20e-36	122.9	1534	1559

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrp 27
           e+qW+Cs C  +Ne++avkC++C++p
   Q: 1534 EGQWDCSLCSVRNEANAVKCVACQNP 1559
           79**********************98 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MRRSKAEVER YIASVQGSAP SPREKSMKGF YFAKLYYEAK EYDLAKKYIS TYINVQERDP 60
KAHRFLGLLY EIEENTDKAV ECYKRSVELN PTQKDLVLKI AELLCKNDVT DGRAKYWVER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCTGGAGA CCGCAGCCGC TGTAGGCCCC AGAGCTGGCC TGCCGCTCCC GGGGAGCCTG 60
GTCGGCGGCA CGATGAGGCG CAGCAAGGCC GAGGTGGAGC GGTACATCGC CTCGGTGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0802--TPR repeat

Interpro

IPR029000--Cyclophilin-like_dom
IPR020892--Cyclophilin-type_PPIase_CS
IPR002130--Cyclophilin-type_PPIase_dom
IPR022011--IR1-M
IPR011993--PH_dom-like
IPR000156--Ran_bind_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR001876--Znf_RanBP2

PROSITE

PS00170--CSA_PPIASE_1
PS50072--CSA_PPIASE_2
PS50196--RANBD1
PS50005--TPR
PS50293--TPR_REGION
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF12185--IR1-M
PF00160--Pro_isomerase
PF00638--Ran_BP1
PF00641--zf-RanBP

PRINTS

PR00153--CSAPPISMRASE

SMART

SM00160--RanBD
SM00028--TPR
SM00547--ZnF_RBZ

Gene Ontology

GO:0005813--C:centrosome
GO:1990723--C:cytoplasmic periphery of the nuclear pore complex
GO:0005739--C:mitochondrion
GO:0005643--C:nuclear pore
GO:0044614--C:nuclear pore cytoplasmic filaments
GO:0003755--F:peptidyl-prolyl cis-trans isomerase activity
GO:0032403--F:protein complex binding
GO:0008536--F:Ran GTPase binding
GO:0008270--F:zinc ion binding
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0033132--P:negative regulation of glucokinase activity
GO:0043547--P:positive regulation of GTPase activity
GO:0046604--P:positive regulation of mitotic centrosome separation
GO:0006457--P:protein folding
GO:0006606--P:protein import into nucleus
GO:0090526--P:regulation of gluconeogenesis involved in cellular glucose homeostasis
GO:0001975--P:response to amphetamine
GO:0006405--P:RNA export from nucleus
GO:0007051--P:spindle organization
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

rno:294429

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002141	Ailuropoda melanoleuca	82.96	0.00e+00	4973.00
IUUC-Apl-004213	Anas platyrhynchos	64.17	0.00e+00	1023.00
IUUC-Aca-005244	Anolis carolinensis	64.98	0.00e+00	2040.00
IUUC-Ame-011486	Astyanax mexicanus	51.79	0.00e+00	1247.00
IUUC-Bta-012952	Bos taurus	79.29	0.00e+00	4699.00
IUUC-Cja-019112	Callithrix jacchus	85.29	0.00e+00	2924.00
IUUC-Cfa-020158	Canis familiaris	76.37	0.00e+00	4423.00
IUUC-Cpo-022292	Cavia porcellus	79.83	0.00e+00	2515.00
IUUC-Csa-023696	Chlorocebus sabaeus	86.92	0.00e+00	2880.00
IUUC-Cho-024560	Choloepus hoffmanni	70.34	0.00e+00	963.00
IUUC-Dre-027540	Danio rerio	47.48	0.00e+00	1337.00
IUUC-Dno-029177	Dasypus novemcinctus	82.26	0.00e+00	4860.00
IUUC-Dor-030161	Dipodomys ordii	79.75	0.00e+00	1545.00
IUUC-Ete-032679	Echinops telfairi	83.04	0.00e+00	1317.00
IUUC-Eca-034415	Equus caballus	81.36	0.00e+00	4795.00
IUUC-Eeu-035195	Erinaceus europaeus	77.42	0.00e+00	2868.00
IUUC-Fca-036339	Felis catus	83.17	0.00e+00	4870.00
IUUC-Fal-036665	Ficedula albicollis	63.20	0.00e+00	2015.00
IUUC-Gmo-038469	Gadus morhua	44.98	0.00e+00	1285.00
IUUC-Gga-041154	Gallus gallus	60.90	0.00e+00	3128.00
IUUC-Gac-042057	Gasterosteus aculeatus	49.89	0.00e+00	2768.00
IUUC-Hsa-046168	Homo sapiens	86.57	0.00e+00	2946.00
IUUC-Itr-049075	Ictidomys tridecemlineatus	84.98	0.00e+00	4517.00
IUUC-Lch-050060	Latimeria chalumnae	58.17	0.00e+00	1826.00
IUUC-Loc-052650	Lepisosteus oculatus	53.92	0.00e+00	2966.00
IUUC-Laf-053667	Loxodonta africana	83.47	0.00e+00	5001.00
IUUC-Mcc-055115	Macaca mulatta	87.09	0.00e+00	2937.00
IUUC-Mga-059419	Meleagris gallopavo	61.61	0.00e+00	3512.00
IUUC-Mmr-061001	Microcebus murinus	85.56	0.00e+00	2993.00
IUUC-Mdo-061922	Monodelphis domestica	70.25	0.00e+00	2167.00
IUUC-Mmu-063291	Mus musculus	93.82	0.00e+00	5611.00
IUUC-Mpu-066011	Mustela putorius furo	82.88	0.00e+00	2541.00
IUUC-Mlu-067422	Myotis lucifugus	78.98	0.00e+00	4695.00
IUUC-Nle-069190	Nomascus leucogenys	84.92	0.00e+00	2788.00
IUUC-Opr-070420	Ochotona princeps	77.59	0.00e+00	2913.00
IUUC-Ont-071362	Oreochromis niloticus	51.57	0.00e+00	2863.00
IUUC-Oan-072832	Ornithorhynchus anatinus	70.54	0.00e+00	3245.00
IUUC-Ocu-073902	Oryctolagus cuniculus	84.12	0.00e+00	5033.00
IUUC-Ola-087304	Oryzias latipes	48.74	0.00e+00	2617.00
IUUC-Oga-088196	Otolemur garnettii	85.08	0.00e+00	5135.00
IUUC-Oar-089627	Ovis aries	78.94	0.00e+00	4676.00
IUUC-Ptr-091152	Pan troglodytes	86.17	0.00e+00	2934.00
IUUC-Pan-091914	Papio anubis	87.09	0.00e+00	2940.00
IUUC-Psi-093994	Pelodiscus sinensis	67.53	0.00e+00	3886.00
IUUC-Pma-094629	Petromyzon marinus	40.92	0.00e+00	850.00
IUUC-Pfo-096897	Poecilia formosa	52.18	0.00e+00	1291.00
IUUC-Pab-097566	Pongo abelii	80.55	0.00e+00	2555.00
IUUC-Pca-100141	Procavia capensis	78.71	0.00e+00	4014.00
IUUC-Pva-102323	Pteropus vampyrus	80.70	0.00e+00	1868.00
IUUC-Sha-106537	Sarcophilus harrisii	72.45	0.00e+00	2511.00
IUUC-Sar-113031	Sorex araneus	86.58	0.00e+00	1229.00
IUUC-Ssc-115622	Sus scrofa	78.29	0.00e+00	4158.00
IUUC-Tgu-116781	Taeniopygia guttata	62.20	0.00e+00	1951.00
IUUC-Tru-118684	Takifugu rubripes	43.37	0.00e+00	1044.00
IUUC-Tsy-119490	Tarsius syrichta	82.87	0.00e+00	2042.00
IUUC-Tbe-127349	Tupaia belangeri	85.61	0.00e+00	1770.00
IUUC-Ttr-128883	Tursiops truncatus	78.14	0.00e+00	3581.00
IUUC-Vpa-130224	Vicugna pacos	77.79	0.00e+00	2866.00
IUUC-Xtr-132557	Xenopus tropicalis	56.95	0.00e+00	3021.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence