iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091649

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03134331

Gene Name

KLHL4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000022075.5	ENSPTRT00000041114.5	ENSPTRP00000037981.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.90e-11	42.0	163	214
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.20e-06	27.8	246	276

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 17   ivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +vL+a S++F a+f+++  e k +++v +++v+p +++ l+++ Ytg l+++e
   Q: 163  LVLSAVSDYFAAMFTNDVLEAK-QEEVRMEGVDPNALNSLVQYAYTGVLQLKE 214
           69*******************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi++f+d+  c++L  +a++++  hF
   Q: 246  PSNCLGIRSFGDAQVCTELLNVAHKYTMEHF 276
           89************************98777 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MSVSGKKEFD VKQILRLRWR WFSHPFQGST NTGSCLQQEG YEHRGTPVQG RKSHSRDRNG 60
LKKSSPVHHN ILAPHNLIVH FQANEDTPKS VPEKNLFKEA CEKRAQDLEM MADDNIEDST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGTGT CTGGCAAGAA AGAGTTTGAT GTGAAACAGA TCCTAAGGCT ACGCTGGAGG 60
TGGTTTAGTC ATCCTTTTCA AGGTTCCACC AACACTGGAA GCTGTCTTCA GCAGGAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005815--C:microtubule organizing center
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001422	Ailuropoda melanoleuca	83.83	0.00e+00	1125.00
IUUC-Aca-004238	Anolis carolinensis	74.90	0.00e+00	1017.00
IUUC-Ame-011287	Astyanax mexicanus	64.29	0.00e+00	772.00
IUUC-Bta-013232	Bos taurus	82.66	0.00e+00	1003.00
IUUC-Cja-018916	Callithrix jacchus	89.41	0.00e+00	1209.00
IUUC-Cfa-020972	Canis familiaris	86.85	0.00e+00	974.00
IUUC-Csa-023849	Chlorocebus sabaeus	90.95	0.00e+00	1264.00
IUUC-Dre-028417	Danio rerio	69.86	0.00e+00	745.00
IUUC-Dor-030708	Dipodomys ordii	78.54	0.00e+00	1055.00
IUUC-Ete-033156	Echinops telfairi	75.83	0.00e+00	732.00
IUUC-Eca-033542	Equus caballus	84.26	0.00e+00	1145.00
IUUC-Fal-036999	Ficedula albicollis	76.08	0.00e+00	1040.00
IUUC-Gga-040215	Gallus gallus	77.22	0.00e+00	1069.00
IUUC-Ggo-045074	Gorilla gorilla	91.92	0.00e+00	1281.00
IUUC-Hsa-046486	Homo sapiens	91.73	0.00e+00	1247.00
IUUC-Loc-052015	Lepisosteus oculatus	72.18	0.00e+00	950.00
IUUC-Laf-053627	Loxodonta africana	83.57	0.00e+00	1165.00
IUUC-Mcc-055418	Macaca mulatta	91.09	0.00e+00	1271.00
IUUC-Meu-056859	Macropus eugenii	67.31	4.00e-124	438.00
IUUC-Mga-059582	Meleagris gallopavo	76.54	0.00e+00	1000.00
IUUC-Mmr-061648	Microcebus murinus	86.35	0.00e+00	1199.00
IUUC-Mmu-063807	Mus musculus	81.45	0.00e+00	1122.00
IUUC-Mpu-066279	Mustela putorius furo	85.99	0.00e+00	965.00
IUUC-Mlu-067981	Myotis lucifugus	82.45	0.00e+00	1152.00
IUUC-Nle-070033	Nomascus leucogenys	90.84	0.00e+00	1233.00
IUUC-Ont-071932	Oreochromis niloticus	69.22	0.00e+00	940.00
IUUC-Ocu-073854	Oryctolagus cuniculus	87.33	0.00e+00	994.00
IUUC-Oar-089952	Ovis aries	84.40	0.00e+00	1170.00
IUUC-Pan-091798	Papio anubis	91.23	0.00e+00	1271.00
IUUC-Psi-093728	Pelodiscus sinensis	75.83	0.00e+00	1046.00
IUUC-Pab-098461	Pongo abelii	90.79	0.00e+00	1264.00
IUUC-Pva-102458	Pteropus vampyrus	84.06	0.00e+00	1030.00
IUUC-Rno-105865	Rattus norvegicus	82.15	0.00e+00	1124.00
IUUC-Ssc-116001	Sus scrofa	86.41	0.00e+00	1202.00
IUUC-Tgu-116994	Taeniopygia guttata	77.05	0.00e+00	1053.00
IUUC-Tbe-128118	Tupaia belangeri	68.28	0.00e+00	807.00
IUUC-Ttr-129220	Tursiops truncatus	77.40	0.00e+00	1039.00
IUUC-Vpa-130811	Vicugna pacos	80.46	0.00e+00	1070.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence