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Tag Content
UUCD2 ID IUUC-Aml-002209
UUCD1 version UUC-AiM-01059
Ensembl Protein ID ENSAMEP00000016980.1
UniProt Accession G1MCA2; G1MCA2_AILME
Genbank Protein ID ENSAMEP00000016980
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID ACTA01161201
Gene Name USP20
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000016078.1 ENSAMET00000017676.1 ENSAMEP00000016980.1
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.40e-107 358.2 147 686
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tG+kNlgN+CYmN++LQ+Lsn+p+l++++le     +    ++++k +l+ks+qkl++e+w  ++ ++v p++l + +k ++++f+gy+
   Q: 147  TGMKNLGNSCYMNAALQALSNCPPLTQFFLE-----CGGLVRTDKKPALCKSYQKLVSEVWhRRRPSYVVPTSLSHGIKLVNPMFRGYA 230
           7******************************.....999999*******************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkk..............eknkpkeeeeeedkselsde.................................. 129
           qqD+qEfl++l+dql+eelk+              +++++++e++e d+s ++de                                  
   Q: 231  QQDTQEFLRCLMDQLHEELKEpvvaaaaalveardSDSSDTDEKREGDRSPSEDEflscdsssdrgegdgqgrggggsqaeaellisde 319
           *******************998987777777666655566666666666666666********************************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 320  agraisekermkdrkfswgqqrtsseqvdedadvdtamaaldeqpaeaqppspgssspcrtpepdneahmrsasrpcspvhhheghskl 408
           ***************************************************************************************** PP
   S: 130  ...........................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke...... 185
                                      ++++k+++++s+isd+F+g++ s ++cl+cd+vs++ e+f+dlslp+pgke+ +k+      
   Q: 409  agsppraspvrmgpsyvlkkaqvlsagSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLAKLhsaiyq 497
           ******************************************************************************99888****** PP
   S: 186  ...........................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLi 231
                                                      +l+dcL++f++++el+g+n+y+ce+ckk+++ +k +k+ +lPe+L+
   Q: 498  napakpgacgdsytaqgwlafiveyirrfvvsctpswfwgpvvTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILC 586
           ***************************************************************************************** PP
   S: 232  lhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevk 318
           +hLkRf  ++e + + ki+++v+fple Ldl+pf+++++++   +   +L++v++H+G+++s HYvay++n  +g+W++fdD++Vtev+
   Q: 587  IHLKRF--RHEVMYSFKISSHVSFPLEgLDLRPFLAKECTS---QXXXDLLSVICHHGTAGSDHYVAYCQNvINGQWYEFDDQYVTEVH 670
           ******..9999*************************9988...5999***********************78999************* PP
   S: 319  eeevleetgstaYvlfYkr 337
           e+ v++   ++aYvlfY++
   Q: 671  ETAVQT---AEAYVLFYRK 686
           ******...********98 PP
   
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
AKMGDTRDLC PHLDSIGEVT KEDLLFKSKG VCQSCGVSGP NLWACLQVSC PYVGCGESFA 60
DHSTIHAQAK KHNLTVNLNT FRVWCYACEK EVFLEQRLAA HPAGPSPRFS EQDAPLPSHP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Aml-002209|DUB,USP|Ailuropoda melanoleuca
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCCAAAATGG GGGACACCAG GGACCTTTGC CCTCACCTTG ACTCCATAGG GGAGGTGACC 60
AAGGAGGACT TGCTGTTCAA ATCTAAGGTA AAGGGTCAGA CCTTCCAGGG CTGAGGACCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Aml-002209|DUB,USP|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
SM00290--ZnF_UBP
Gene Ontology

GO:0005813--C:centrosome
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003351 Anas platyrhynchos 83.95 0.00e+00 1535.00
IUUC-Aca-005077 Anolis carolinensis 75.73 0.00e+00 1095.00
IUUC-Ame-011777 Astyanax mexicanus 74.92 0.00e+00 1321.00
IUUC-Bta-013063 Bos taurus 93.77 0.00e+00 1651.00
IUUC-Cja-019868 Callithrix jacchus 91.48 0.00e+00 1664.00
IUUC-Cfa-020761 Canis familiaris 95.19 0.00e+00 1697.00
IUUC-Cpo-022267 Cavia porcellus 85.82 0.00e+00 1528.00
IUUC-Csa-024251 Chlorocebus sabaeus 93.01 0.00e+00 1679.00
IUUC-Cho-024483 Choloepus hoffmanni 92.45 2.00e-117 416.00
IUUC-Csv-025889 Ciona savignyi 43.71 2.00e-35 141.00
IUUC-Dre-028061 Danio rerio 72.99 0.00e+00 1186.00
IUUC-Dno-029423 Dasypus novemcinctus 92.90 0.00e+00 1669.00
IUUC-Dor-030877 Dipodomys ordii 89.67 0.00e+00 1064.00
IUUC-Dme-031837 Drosophila melanogaster 49.23 1.00e-133 470.00
IUUC-Ete-032802 Echinops telfairi 78.92 5.00e-135 475.00
IUUC-Eca-034283 Equus caballus 92.58 0.00e+00 1653.00
IUUC-Eeu-034620 Erinaceus europaeus 90.20 0.00e+00 1164.00
IUUC-Fca-036357 Felis catus 94.86 0.00e+00 1675.00
IUUC-Fal-037411 Ficedula albicollis 84.87 0.00e+00 1538.00
IUUC-Gga-041101 Gallus gallus 83.86 0.00e+00 1513.00
IUUC-Gac-041315 Gasterosteus aculeatus 73.42 0.00e+00 1304.00
IUUC-Ggo-045600 Gorilla gorilla 92.52 0.00e+00 1642.00
IUUC-Hsa-045825 Homo sapiens 93.22 0.00e+00 1654.00
IUUC-Itr-048549 Ictidomys tridecemlineatus 79.68 0.00e+00 1372.00
IUUC-Lch-050002 Latimeria chalumnae 73.89 0.00e+00 1293.00
IUUC-Loc-052574 Lepisosteus oculatus 76.42 0.00e+00 1384.00
IUUC-Laf-054428 Loxodonta africana 91.49 0.00e+00 1624.00
IUUC-Mcc-055736 Macaca mulatta 92.79 0.00e+00 1675.00
IUUC-Mga-059781 Meleagris gallopavo 83.44 0.00e+00 1516.00
IUUC-Mdo-063048 Monodelphis domestica 86.94 0.00e+00 1516.00
IUUC-Mmu-064079 Mus musculus 91.16 0.00e+00 1609.00
IUUC-Mpu-066616 Mustela putorius furo 93.68 0.00e+00 1714.00
IUUC-Mlu-067294 Myotis lucifugus 91.69 0.00e+00 1592.00
IUUC-Nle-070015 Nomascus leucogenys 92.79 0.00e+00 1616.00
IUUC-Opr-070328 Ochotona princeps 91.28 0.00e+00 1627.00
IUUC-Ont-071464 Oreochromis niloticus 73.56 0.00e+00 1288.00
IUUC-Oan-073259 Ornithorhynchus anatinus 77.66 0.00e+00 1293.00
IUUC-Ocu-074630 Oryctolagus cuniculus 89.29 0.00e+00 1553.00
IUUC-Ola-087240 Oryzias latipes 73.10 0.00e+00 1271.00
IUUC-Oga-088761 Otolemur garnettii 90.71 0.00e+00 1646.00
IUUC-Oar-089490 Ovis aries 88.42 0.00e+00 1495.00
IUUC-Ptr-091662 Pan troglodytes 93.33 0.00e+00 1654.00
IUUC-Pan-092199 Papio anubis 92.58 0.00e+00 1670.00
IUUC-Psi-093726 Pelodiscus sinensis 85.61 0.00e+00 1536.00
IUUC-Pma-094389 Petromyzon marinus 63.42 2.00e-98 351.00
IUUC-Pab-098632 Pongo abelii 92.90 0.00e+00 1643.00
IUUC-Pca-100614 Procavia capensis 84.39 0.00e+00 1261.00
IUUC-Pva-102922 Pteropus vampyrus 91.57 0.00e+00 971.00
IUUC-Rno-105215 Rattus norvegicus 90.82 0.00e+00 1612.00
IUUC-Sha-106601 Sarcophilus harrisii 84.88 0.00e+00 1494.00
IUUC-Ssc-115533 Sus scrofa 91.47 0.00e+00 1624.00
IUUC-Tgu-117364 Taeniopygia guttata 84.61 0.00e+00 1499.00
IUUC-Tru-117770 Takifugu rubripes 71.14 0.00e+00 1261.00
IUUC-Tni-120001 Tetraodon nigroviridis 71.86 0.00e+00 1236.00
IUUC-Ttr-128732 Tursiops truncatus 93.99 0.00e+00 1671.00
IUUC-Xtr-132157 Xenopus tropicalis 75.38 0.00e+00 1338.00
Created Date 25-Jun-2017

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