iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073169

Ensembl Protein ID

ENSOANP00000015019.2

UniProt Accession

F6ZXZ0; F6ZXZ0_ORNAN

Protein Name

Uncharacterized protein

Gene Name

MAP3K5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000009449.3	ENSOANT00000015022.2	ENSOANP00000015019.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	93.56	0.00e+00	2250.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

FSADIAVVEM SDAFRQPSLF YHLGVRESFS MANNIILYCD TNSDSLQSLK EIICQKNTMC 60
TGNYTFVPYM ITPHNKVYCC DSSFMKGLTE LMQPNFELLL GPICLPLVDR FTQLLKVAQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTCTCTGCAG ACATCGCCGT GGTGGAGATG AGCGACGCTT TCCGGCAGCC GTCCTTGTTT 60
TACCACCTTG GGGTGAGGGA GAGCTTCAGC ATGGCCAACA ACATCATCCT CTACTGTGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF13281--DUF4071
PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0000186--P:activation of MAPKK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	93.49	0.00e+00	2158.00
IUUC-Apl-003713	Anas platyrhynchos	89.65	0.00e+00	2083.00
IUUC-Aca-005331	Anolis carolinensis	88.37	0.00e+00	2085.00
IUUC-Ame-011158	Astyanax mexicanus	75.93	0.00e+00	1780.00
IUUC-Bta-012770	Bos taurus	93.56	0.00e+00	2243.00
IUUC-Cja-019656	Callithrix jacchus	93.15	0.00e+00	2234.00
IUUC-Cfa-020488	Canis familiaris	93.06	0.00e+00	2230.00
IUUC-Cpo-022516	Cavia porcellus	91.76	0.00e+00	2145.00
IUUC-Cre-022653	Chlamydomonas reinhardtii	37.15	1.00e-30	126.00
IUUC-Csa-023104	Chlorocebus sabaeus	93.60	0.00e+00	2233.00
IUUC-Cho-024379	Choloepus hoffmanni	86.25	0.00e+00	1191.00
IUUC-Dre-028836	Danio rerio	75.81	0.00e+00	1824.00
IUUC-Dno-029842	Dasypus novemcinctus	91.09	0.00e+00	2144.00
IUUC-Dor-030990	Dipodomys ordii	93.25	0.00e+00	1903.00
IUUC-Ete-032693	Echinops telfairi	83.29	0.00e+00	1778.00
IUUC-Eca-033337	Equus caballus	92.82	0.00e+00	2256.00
IUUC-Eeu-034602	Erinaceus europaeus	77.49	0.00e+00	1788.00
IUUC-Fca-035954	Felis catus	92.67	0.00e+00	1880.00
IUUC-Fal-037358	Ficedula albicollis	88.48	0.00e+00	2106.00
IUUC-Gmo-038836	Gadus morhua	81.00	0.00e+00	1678.00
IUUC-Gga-040443	Gallus gallus	89.24	0.00e+00	2143.00
IUUC-Gac-041634	Gasterosteus aculeatus	77.35	0.00e+00	1876.00
IUUC-Ggo-045263	Gorilla gorilla	91.47	0.00e+00	2167.00
IUUC-Hsa-046906	Homo sapiens	93.56	0.00e+00	2250.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	90.66	0.00e+00	1052.00
IUUC-Lch-050213	Latimeria chalumnae	79.56	0.00e+00	1828.00
IUUC-Loc-051829	Lepisosteus oculatus	76.69	0.00e+00	1819.00
IUUC-Laf-053538	Loxodonta africana	93.07	0.00e+00	2228.00
IUUC-Mcc-054776	Macaca mulatta	93.40	0.00e+00	2246.00
IUUC-Mga-059636	Meleagris gallopavo	89.24	0.00e+00	2140.00
IUUC-Mmr-061323	Microcebus murinus	93.40	0.00e+00	2207.00
IUUC-Mdo-062146	Monodelphis domestica	93.57	0.00e+00	2179.00
IUUC-Mmu-064022	Mus musculus	93.31	0.00e+00	2222.00
IUUC-Mpu-066531	Mustela putorius furo	91.02	0.00e+00	2229.00
IUUC-Mlu-068181	Myotis lucifugus	91.36	0.00e+00	2201.00
IUUC-Nle-069758	Nomascus leucogenys	93.60	0.00e+00	2234.00
IUUC-Opr-070531	Ochotona princeps	84.68	0.00e+00	1429.00
IUUC-Ont-072014	Oreochromis niloticus	78.32	0.00e+00	1850.00
IUUC-Ocu-074050	Oryctolagus cuniculus	88.56	0.00e+00	2092.00
IUUC-Ola-086941	Oryzias latipes	80.38	0.00e+00	1549.00
IUUC-Oga-088796	Otolemur garnettii	92.99	0.00e+00	2192.00
IUUC-Oar-090445	Ovis aries	94.03	0.00e+00	2244.00
IUUC-Ptr-090846	Pan troglodytes	93.64	0.00e+00	2253.00
IUUC-Pan-091986	Papio anubis	93.48	0.00e+00	2248.00
IUUC-Psi-093805	Pelodiscus sinensis	89.81	0.00e+00	2243.00
IUUC-Pfo-097301	Poecilia formosa	78.52	0.00e+00	1863.00
IUUC-Pab-097662	Pongo abelii	93.48	0.00e+00	2249.00
IUUC-Pca-100755	Procavia capensis	70.68	0.00e+00	702.00
IUUC-Pva-102280	Pteropus vampyrus	84.35	0.00e+00	1981.00
IUUC-Rno-105547	Rattus norvegicus	91.76	0.00e+00	2198.00
IUUC-Sha-106859	Sarcophilus harrisii	93.40	0.00e+00	2148.00
IUUC-Sar-113714	Sorex araneus	81.06	0.00e+00	1879.00
IUUC-Tgu-117116	Taeniopygia guttata	87.55	0.00e+00	2082.00
IUUC-Tru-118088	Takifugu rubripes	77.64	0.00e+00	1894.00
IUUC-Tsy-119616	Tarsius syrichta	89.00	0.00e+00	1821.00
IUUC-Tni-120284	Tetraodon nigroviridis	76.19	0.00e+00	1860.00
IUUC-Tbe-127900	Tupaia belangeri	91.80	0.00e+00	833.00
IUUC-Ttr-128294	Tursiops truncatus	82.07	0.00e+00	1903.00
IUUC-Vpa-130470	Vicugna pacos	84.52	0.00e+00	1963.00
IUUC-Xtr-132396	Xenopus tropicalis	79.87	0.00e+00	1891.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence