iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020321

Ensembl Protein ID

ENSCAFP00000015359.3

UniProt Accession

E2RNK0; E2RNK0_CANLF

Genbank Protein ID

ENSCAFP00000015359

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03017717

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000010438.3	ENSCAFT00000016597.3	ENSCAFP00000015359.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	6.50e-40	135.8	9	80

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfref 72
           d+ +r lls++++rv+++++v++vld yl  fl+ee+ke+i++ a++ gn qaaelLL+tL    +  gW+r+ 
   Q: 9    DQSFRHLLSCFRARVKTYIQVEPVLD-YLN-FLPEEVKEQIQRKAANAGNLQAAELLLSTLekgAWPPGWTRQV 80
           6779**********************.***.****************************************975 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MWSGRPSADQ SFRHLLSCFR ARVKTYIQVE PVLDYLNFLP EEVKEQIQRK AANAGNLQAA 60
ELLLSTLEKG AWPPGWTRQV LVALQSAGSV LASRYLNPEL ADLPSPSAEN AHDQCLQLLH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGAGCG GCCGCCCCTC CGCGGACCAG AGCTTCCGCC ATCTCCTGTC GTGCTTCAGG 60
GCGCGGGTGA AAACGTACAT CCAGGTGGAG CCGGTCCTGG ACTACCTGAA CTTCCTGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR001315--CARD
IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS50209--CARD
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation
GO:0042981--P:regulation of apoptotic process

KEGG

cfa:488371

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	89.46	0.00e+00	1735.00
IUUC-Apl-003900	Anas platyrhynchos	58.96	0.00e+00	1139.00
IUUC-Aca-005329	Anolis carolinensis	57.20	0.00e+00	985.00
IUUC-Ame-011305	Astyanax mexicanus	47.10	0.00e+00	842.00
IUUC-Bta-012361	Bos taurus	80.86	0.00e+00	1528.00
IUUC-Cja-018760	Callithrix jacchus	81.62	0.00e+00	1516.00
IUUC-Cpo-022450	Cavia porcellus	75.70	0.00e+00	1489.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	32.48	5.00e-12	67.00
IUUC-Csa-024194	Chlorocebus sabaeus	83.58	0.00e+00	1523.00
IUUC-Cho-024364	Choloepus hoffmanni	73.72	0.00e+00	1026.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	22.70	2.00e-19	92.00
IUUC-Dre-028305	Danio rerio	53.01	0.00e+00	704.00
IUUC-Dno-029831	Dasypus novemcinctus	82.28	0.00e+00	1566.00
IUUC-Dor-030410	Dipodomys ordii	74.46	0.00e+00	1167.00
IUUC-Ete-032950	Echinops telfairi	73.52	1.00e-178	620.00
IUUC-Eca-034279	Equus caballus	83.38	0.00e+00	1584.00
IUUC-Eeu-034678	Erinaceus europaeus	76.34	0.00e+00	1484.00
IUUC-Fca-035618	Felis catus	91.77	0.00e+00	1035.00
IUUC-Fal-037106	Ficedula albicollis	67.27	0.00e+00	959.00
IUUC-Gmo-038598	Gadus morhua	48.61	0.00e+00	655.00
IUUC-Gga-040467	Gallus gallus	59.82	0.00e+00	1133.00
IUUC-Gac-042316	Gasterosteus aculeatus	46.27	0.00e+00	782.00
IUUC-Ggo-045461	Gorilla gorilla	82.80	0.00e+00	1511.00
IUUC-Hsa-045771	Homo sapiens	82.70	0.00e+00	1509.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	79.96	0.00e+00	1494.00
IUUC-Lch-049913	Latimeria chalumnae	63.46	0.00e+00	899.00
IUUC-Loc-052768	Lepisosteus oculatus	52.54	0.00e+00	936.00
IUUC-Laf-053933	Loxodonta africana	81.38	0.00e+00	1540.00
IUUC-Mcc-054695	Macaca mulatta	83.68	0.00e+00	1527.00
IUUC-Meu-056829	Macropus eugenii	71.76	0.00e+00	1089.00
IUUC-Mga-059205	Meleagris gallopavo	59.14	0.00e+00	1124.00
IUUC-Mmr-060703	Microcebus murinus	82.27	0.00e+00	1526.00
IUUC-Mdo-063079	Monodelphis domestica	68.90	0.00e+00	1356.00
IUUC-Mmu-064066	Mus musculus	76.76	0.00e+00	1514.00
IUUC-Mpu-066261	Mustela putorius furo	89.35	0.00e+00	1706.00
IUUC-Mlu-068196	Myotis lucifugus	81.52	0.00e+00	1513.00
IUUC-Nle-069479	Nomascus leucogenys	80.25	0.00e+00	1467.00
IUUC-Opr-070717	Ochotona princeps	70.55	0.00e+00	1085.00
IUUC-Ont-071702	Oreochromis niloticus	46.48	0.00e+00	816.00
IUUC-Oan-073639	Ornithorhynchus anatinus	65.11	0.00e+00	1129.00
IUUC-Ocu-074521	Oryctolagus cuniculus	82.11	0.00e+00	1550.00
IUUC-Ola-086351	Oryzias latipes	45.82	0.00e+00	787.00
IUUC-Oga-088539	Otolemur garnettii	78.79	0.00e+00	1469.00
IUUC-Oar-090186	Ovis aries	81.05	0.00e+00	1511.00
IUUC-Ptr-090575	Pan troglodytes	79.86	0.00e+00	1463.00
IUUC-Pan-092371	Papio anubis	83.87	0.00e+00	1528.00
IUUC-Psi-093072	Pelodiscus sinensis	62.25	0.00e+00	1195.00
IUUC-Pma-094345	Petromyzon marinus	41.87	1.00e-87	316.00
IUUC-Pfo-096401	Poecilia formosa	51.80	0.00e+00	675.00
IUUC-Pab-097623	Pongo abelii	81.62	0.00e+00	1499.00
IUUC-Pca-100993	Procavia capensis	75.11	0.00e+00	1259.00
IUUC-Pva-102227	Pteropus vampyrus	76.83	0.00e+00	1431.00
IUUC-Rno-105198	Rattus norvegicus	76.39	0.00e+00	1511.00
IUUC-Sha-107622	Sarcophilus harrisii	71.35	0.00e+00	1367.00
IUUC-Spo-108161	Schizosaccharomyces pombe	28.16	3.60e-02	33.90
IUUC-Sar-113625	Sorex araneus	66.78	0.00e+00	704.00
IUUC-Tgu-117486	Taeniopygia guttata	59.63	0.00e+00	1091.00
IUUC-Tru-118445	Takifugu rubripes	44.91	0.00e+00	793.00
IUUC-Tsy-119512	Tarsius syrichta	79.37	0.00e+00	1431.00
IUUC-Tni-120711	Tetraodon nigroviridis	44.69	0.00e+00	805.00
IUUC-Tbe-127644	Tupaia belangeri	70.90	0.00e+00	1281.00
IUUC-Ttr-128989	Tursiops truncatus	77.07	0.00e+00	1494.00
IUUC-Vpa-130587	Vicugna pacos	78.20	0.00e+00	1250.00
IUUC-Xtr-132127	Xenopus tropicalis	52.18	0.00e+00	977.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence