iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-086820

Ensembl Protein ID

ENSORLP00000011762.1

UniProt Accession

H2M039; H2M039_ORYLA

Genbank Protein ID

ENSORLP00000011762

Protein Name

Phosphoinositide phospholipase C

Genbank Nucleotide ID

BAAF04002734

Gene Name

plcg1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000009380.1	ENSORLT00000011763.1	ENSORLP00000011762.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.60e-11	43.6	790	845

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v+++y+y+aq ddeL+++k  ++  +  ++q++gW+kg     +k+  fP+n+ve+++
   Q: 790  TVRAMYEYKAQRDDELSFTKDTIISNV--DKQEGGWWKGD-YGGKKQFWFPANYVEEIS 845
           799******************999999..9*********3.44555567*******986 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MAGTSGFFSN GPVPWMDNDT EMNNLYRDLE LGTVLTLFYS KKSQRPERRT FLVKLETRTI 60
IWTRSTDKIE GEIDIREIKE IRSGQKSRDF ERYTEDPSVR LDQAHCFVIL YGTEFRLKSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGGGA CCTCTGGCTT CTTTTCCAAT GGACCTGTTC CGTGGATGGA CAACGACACA 60
GAGATGAACA ACCTTTACAG AGACTTGGAG CTTGGCACTG TACTGACATT GTTTTATTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer

Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028380--PLC-gamma1
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS00018--EF_HAND_1
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00168--C2
PF00169--PH
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0001525--P:angiogenesis
GO:0048844--P:artery morphogenesis
GO:0031101--P:fin regeneration
GO:0030851--P:granulocyte differentiation
GO:0060218--P:hematopoietic stem cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0009395--P:phospholipid catabolic process
GO:0035477--P:regulation of angioblast cell migration involved in selective angioblast sprouting
GO:0008016--P:regulation of heart contraction
GO:0001570--P:vasculogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001452	Ailuropoda melanoleuca	72.52	0.00e+00	2004.00
IUUC-Apl-003541	Anas platyrhynchos	65.35	0.00e+00	1714.00
IUUC-Aca-005291	Anolis carolinensis	73.73	0.00e+00	1999.00
IUUC-Ame-011004	Astyanax mexicanus	75.96	0.00e+00	1996.00
IUUC-Bta-012660	Bos taurus	73.39	0.00e+00	1911.00
IUUC-Cja-019206	Callithrix jacchus	72.67	0.00e+00	1987.00
IUUC-Cfa-020257	Canis familiaris	73.64	0.00e+00	1929.00
IUUC-Cpo-022391	Cavia porcellus	68.35	0.00e+00	1843.00
IUUC-Csa-024170	Chlorocebus sabaeus	75.03	0.00e+00	1486.00
IUUC-Cin-025520	Ciona intestinalis	45.98	0.00e+00	1078.00
IUUC-Dre-027944	Danio rerio	80.51	0.00e+00	2130.00
IUUC-Dno-029440	Dasypus novemcinctus	73.43	0.00e+00	1842.00
IUUC-Dor-031001	Dipodomys ordii	72.73	0.00e+00	2001.00
IUUC-Eca-033809	Equus caballus	73.56	0.00e+00	1930.00
IUUC-Fca-036510	Felis catus	73.72	0.00e+00	1930.00
IUUC-Fal-037541	Ficedula albicollis	74.01	0.00e+00	1825.00
IUUC-Gmo-038630	Gadus morhua	73.13	0.00e+00	1631.00
IUUC-Gga-040142	Gallus gallus	73.55	0.00e+00	1974.00
IUUC-Ggo-045063	Gorilla gorilla	72.73	0.00e+00	2009.00
IUUC-Hsa-046428	Homo sapiens	72.66	0.00e+00	2008.00
IUUC-Itr-048245	Ictidomys tridecemlineatus	73.33	0.00e+00	1980.00
IUUC-Lch-049766	Latimeria chalumnae	73.37	0.00e+00	1877.00
IUUC-Loc-052285	Lepisosteus oculatus	81.76	0.00e+00	2236.00
IUUC-Laf-053365	Loxodonta africana	73.08	0.00e+00	1914.00
IUUC-Mcc-054871	Macaca mulatta	72.82	0.00e+00	1995.00
IUUC-Meu-056724	Macropus eugenii	69.27	0.00e+00	1767.00
IUUC-Mga-059329	Meleagris gallopavo	73.03	0.00e+00	1875.00
IUUC-Mmr-061110	Microcebus murinus	73.26	0.00e+00	2003.00
IUUC-Mdo-062448	Monodelphis domestica	73.41	0.00e+00	2023.00
IUUC-Mmu-063565	Mus musculus	72.82	0.00e+00	1998.00
IUUC-Mpu-066683	Mustela putorius furo	72.89	0.00e+00	2009.00
IUUC-Mlu-067779	Myotis lucifugus	73.40	0.00e+00	1929.00
IUUC-Nle-069219	Nomascus leucogenys	77.16	0.00e+00	1732.00
IUUC-Opr-070766	Ochotona princeps	69.50	0.00e+00	1135.00
IUUC-Ont-072524	Oreochromis niloticus	87.85	0.00e+00	2300.00
IUUC-Oan-073214	Ornithorhynchus anatinus	60.38	2.00e-35	141.00
IUUC-Ocu-074361	Oryctolagus cuniculus	72.87	0.00e+00	1966.00
IUUC-Oga-088172	Otolemur garnettii	73.04	0.00e+00	2013.00
IUUC-Oar-090306	Ovis aries	71.57	0.00e+00	1850.00
IUUC-Ptr-090682	Pan troglodytes	72.73	0.00e+00	2009.00
IUUC-Pan-092835	Papio anubis	73.68	0.00e+00	1457.00
IUUC-Psi-093344	Pelodiscus sinensis	72.76	0.00e+00	1960.00
IUUC-Pfo-096984	Poecilia formosa	84.24	0.00e+00	2225.00
IUUC-Pab-097871	Pongo abelii	73.41	0.00e+00	1987.00
IUUC-Pca-100772	Procavia capensis	66.99	0.00e+00	1812.00
IUUC-Pva-102790	Pteropus vampyrus	73.33	0.00e+00	1971.00
IUUC-Rno-105974	Rattus norvegicus	72.58	0.00e+00	2011.00
IUUC-Sar-112995	Sorex araneus	71.94	0.00e+00	1943.00
IUUC-Ssc-115360	Sus scrofa	73.54	0.00e+00	2003.00
IUUC-Tgu-116585	Taeniopygia guttata	70.79	0.00e+00	1871.00
IUUC-Tru-117742	Takifugu rubripes	87.81	0.00e+00	2367.00
IUUC-Tsy-119259	Tarsius syrichta	76.19	0.00e+00	692.00
IUUC-Tni-120553	Tetraodon nigroviridis	88.94	0.00e+00	1622.00
IUUC-Tbe-127504	Tupaia belangeri	65.01	0.00e+00	1083.00
IUUC-Xtr-132862	Xenopus tropicalis	68.06	0.00e+00	1818.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence