iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048627

Ensembl Protein ID

ENSSTOP00000017360.1

UniProt Accession

I3MZ14; I3MZ14_ICTTR

Genbank Protein ID

ENSSTOP00000017360

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01051160

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000011792.2	ENSSTOT00000011796.2	ENSSTOP00000017360.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.30e-12	47.8	109	168

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 109  CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 168
           9*****************************77.......4566677678****************98 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

AARWRHSRSS ACRPRPLQIR VCGKRGGAET RPGRGEDGPA GQTDRGPGGR RAAQRSHPPW 60
IRRQPGPGLP TCPPGECAGQ TMLDTMEAPG HSRQLLLQLN NQRTKGFLCD VIIVVQNALF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGCGAGGT GGCGCCATAG CCGCAGCAGC GCCTGCCGGC CCCGACCGCT CCAGATAAGA 60
GTGTGCGGAA AGCGCGGCGG GGCTGAGACG CGACCAGGAC GCGGGGAGGA CGGACCAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	92.14	1.00e-151	530.00
IUUC-Aca-004680	Anolis carolinensis	92.86	6.00e-63	234.00
IUUC-Ame-010967	Astyanax mexicanus	61.16	2.00e-94	340.00
IUUC-Bta-013567	Bos taurus	96.81	1.00e-161	563.00
IUUC-Cja-019621	Callithrix jacchus	95.56	4.00e-60	222.00
IUUC-Cfa-020731	Canis familiaris	95.99	0.00e+00	873.00
IUUC-Cpo-021326	Cavia porcellus	94.36	0.00e+00	1048.00
IUUC-Csa-023645	Chlorocebus sabaeus	95.58	0.00e+00	863.00
IUUC-Dre-028027	Danio rerio	59.70	5.00e-95	342.00
IUUC-Dno-028900	Dasypus novemcinctus	92.80	0.00e+00	910.00
IUUC-Fal-036980	Ficedula albicollis	61.99	2.00e-114	406.00
IUUC-Gga-040708	Gallus gallus	70.61	2.00e-109	389.00
IUUC-Ggo-044591	Gorilla gorilla	99.41	2.00e-139	489.00
IUUC-Hsa-046769	Homo sapiens	95.86	0.00e+00	850.00
IUUC-Loc-051883	Lepisosteus oculatus	62.69	1.00e-95	343.00
IUUC-Laf-053358	Loxodonta africana	91.86	5.00e-166	577.00
IUUC-Mcc-054981	Macaca mulatta	95.54	0.00e+00	848.00
IUUC-Meu-056181	Macropus eugenii	69.53	7.00e-106	377.00
IUUC-Mga-059592	Meleagris gallopavo	73.20	5.00e-107	380.00
IUUC-Mmr-061560	Microcebus murinus	94.84	0.00e+00	853.00
IUUC-Mdo-062511	Monodelphis domestica	81.45	2.00e-90	326.00
IUUC-Mmu-064258	Mus musculus	94.49	0.00e+00	983.00
IUUC-Mpu-065911	Mustela putorius furo	95.96	0.00e+00	857.00
IUUC-Mlu-067575	Myotis lucifugus	80.88	3.00e-134	471.00
IUUC-Ont-072493	Oreochromis niloticus	65.13	3.00e-80	292.00
IUUC-Ola-086584	Oryzias latipes	61.78	4.00e-90	325.00
IUUC-Oga-088774	Otolemur garnettii	94.48	0.00e+00	900.00
IUUC-Ptr-090491	Pan troglodytes	98.81	5.00e-126	444.00
IUUC-Pma-094179	Petromyzon marinus	70.51	3.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	58.86	2.00e-88	320.00
IUUC-Pab-098488	Pongo abelii	95.67	2.00e-171	595.00
IUUC-Pca-100667	Procavia capensis	95.20	1.00e-143	503.00
IUUC-Pva-102421	Pteropus vampyrus	95.86	0.00e+00	862.00
IUUC-Rno-105528	Rattus norvegicus	91.52	0.00e+00	816.00
IUUC-Sar-113478	Sorex araneus	98.76	3.00e-119	422.00
IUUC-Ssc-115420	Sus scrofa	92.90	0.00e+00	863.00
IUUC-Tgu-116642	Taeniopygia guttata	71.57	1.00e-110	393.00
IUUC-Tru-118583	Takifugu rubripes	60.44	3.00e-84	305.00
IUUC-Xtr-132210	Xenopus tropicalis	59.51	0.00e+00	682.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence